期刊： HUMAN MOLECULAR GENETICS, 2021; 30 (10)
The purpose of this study is to study the neuroprotective role of selective serotonin reuptake inhibitor (SSRI), citalopram, against Alzheimer's disea......
期刊： HUMAN MOLECULAR GENETICS, 2021; 30 (11)
Progressive degeneration of retinal ganglion cells (RGCs) is a major characteristic of glaucoma, whose underlying mechanisms are still largely unknown......
期刊： HUMAN MOLECULAR GENETICS, 2021; 30 (17)
Although dozens of susceptibility loci have been identified for lung cancer in genome-wide association studies (GWASs), the susceptibility genes and u......
期刊： HUMAN MOLECULAR GENETICS, 2021; 30 (3-4)
Ankylosing spondylitis (AS) is a rheumatic disease with pathological osteogenesis that causes bony ankylosis and even deformity over time. Mesenchymal......
期刊： HUMAN MOLECULAR GENETICS, 2021; 30 (7)
Oogenesis is a highly regulated process and its basic cellular events are evolutionarily conserved. However, the time spans of oogenesis differ substa......
期刊： HUMAN MOLECULAR GENETICS, 2021; 30 (10)
GGGGCC repeats in a non-coding region of the C9orf72 gene have been identified as a major genetic cause of amyotrophic lateral sclerosis (ALS) and fro......
期刊： HUMAN MOLECULAR GENETICS, 2021; 30 (11)
P2RX2 encodes the P2X2 receptor, which is an adenosine triphosphate (ATP) gated (purinoreceptor) ion channel. P2RX2 c. 178G > T (p.V60L) mutation w......
期刊： HUMAN MOLECULAR GENETICS, 2021; 30 (5)
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gut. Genetic association studies have identified the highly variable human l......
期刊： HUMAN MOLECULAR GENETICS, 2021; 30 (10)
Transcriptome-wide association study (TWAS) is an important integrative method for identifying genes that are causally associated with phenotypes. A k......
期刊： HUMAN MOLECULAR GENETICS, 2021; 30 (11)
Craniofacial microsomia (CFM, OMIM%164 210) is one of the most common congenital facial abnormalities worldwide, but it's genetic risk factors and env......
期刊： HUMAN MOLECULAR GENETICS, 2021; 30 (5)
Most genetic variants for colorectal cancer (CRC) identified in genome-wide association studies (GWAS) are located in intergenic regions, implying pat......
期刊： HUMAN MOLECULAR GENETICS, 2021; 30 (10)
The ten-eleven translocation (Tet) family of dioxygenases convert 5-methylcytosine to 5-hydroxymethylcytosine (5hmC). Previous studies have shown that......
期刊： HUMAN MOLECULAR GENETICS, 2021; 30 (17)
CLP1, TSEN complex, and VCP are evolutionarily conserved proteins whose mutations are associated with neurodegenerative diseases. In this study, we ha......
期刊： HUMAN MOLECULAR GENETICS, 2021; 30 (14)
Delta R4-R23/Delta CT micro-dystrophin (mu Dys) is a miniaturized version of dystrophin currently evaluated in a Duchenne muscular dystrophy (DMD) gen......
期刊： HUMAN MOLECULAR GENETICS, 2021; 30 (17)
Duchenne muscular dystrophy (DMD) is an X-linked neuromuscular disease characterized by progressive wasting of skeletal muscles. The neuromuscular jun......
