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Downregulation of TOP2 modulates neurodegeneration caused by GGGGCC expanded repeats

Jiao, B; Wang, ML; Feng, H; Bao, H; Zhang, FR; Wu, H; Wang, JL; Tang, BS; Jin, P; Shen, L

Shen, L (corresponding author), Cent South Univ, Xiangya Hosp, Dept Neurol, 87 Xiangya Rd, Changsha 410008, Hunan, Peoples R China.; Jin, P (corresponding author), Emory Univ, Sch Med, Dept Human Genet, Atlanta, GA 30322 USA.

HUMAN MOLECULAR GENETICS, 2021; 30 (10): 893

Abstract

GGGGCC repeats in a non-coding region of the C9orf72 gene have been identified as a major genetic cause of amyotrophic lateral sclerosis (ALS) and fro......

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