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Loss of ten-eleven translocation 2 induces cardiac hypertrophy and fibrosis through modulating ERK signaling pathway

Tao, HK; Xu, WZ; Qu, WZ; Gao, H; Zhang, JY; Cheng, XJ; Liu, N; Chen, JH; Xu, GL; Li, XK; Shu, Q

Li, XK; Shu, Q (corresponding author), Zhejiang Univ, Childrens Hosp, Sch Med, Hangzhou 310052, Peoples R China.; Li, XK (corresponding author), Zhejiang Univ, Sch Med, Inst Translat Med, Hangzhou 310029, Peoples R China.; Li, XK; Shu, Q (corresponding author), Natl Clin Res Ctr Child Hlth, Hangzhou 310052, Peoples R China.

HUMAN MOLECULAR GENETICS, 2021; 30 (10): 865

Abstract

The ten-eleven translocation (Tet) family of dioxygenases convert 5-methylcytosine to 5-hydroxymethylcytosine (5hmC). Previous studies have shown that......

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