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Asian Pac J Allergy Immunol:皮刺测试阴性慢性鼻炎患者屋尘螨局部过敏性鼻炎患病率研究

2019-04-09 AlexYang MedSci原创

部过敏性鼻炎(LAR)是一种局部的过敏性响应且无系统特应性反应,可以通过特异性免疫球蛋白E(slgE)的局部产生和NAPT的阳性反应来鉴定(鼻腔过敏原激发试验)。最近,有研究人员调查了LAR在慢性鼻炎(CR)且对屋尘螨(Dp)皮刺测试阴性的成年人中的患病率情况,并且与非过敏性鼻炎(NAR)进行了比较来评估LAR的临床特性。研究包括了那些具有CR历史且对Dp皮刺测试阴性的患者,时间为2015年1月到

局部过敏性鼻炎(LAR)是一种局部的过敏性响应且无系统特应性反应,可以通过特异性免疫球蛋白E(slgE)的局部产生和NAPT的阳性反应来鉴定(鼻腔过敏原激发试验)。最近,有研究人员调查了LAR在慢性鼻炎(CR)且对屋尘螨(Dp)皮刺测试阴性的成年人中的患病率情况,并且与非过敏性鼻炎(NAR)进行了比较来评估LAR的临床特性。

研究包括了那些具有CR历史且对Dp皮刺测试阴性的患者,时间为2015年1月到2016年4月。研究共包括了62名CR患者。CR患者中NAPT-Dp阳性比例为15/62(24.2%)。大多数LAR患者为女性(73.3%),患者的平均年龄为36.1±10.4岁。患者特性评估阐释了只有打喷嚏在2个小组之间具有统计学显著差异(OR: 7.75, 95%CI: 1.91-31.48; p=0.002)。

最后,研究人员指出,Dp的LAR在皮刺测试阴性CR患者中的患病率为24.2%。大多数LAR患者的持续性严重度为中度到重度,且LAR的临床特性中只有打喷嚏是显著的症状。

原始出处:

Tantilipikorn P, Siriboonkoom P, Sookrung N et al. Prevalence of local allergic rhinitis to Dermatophagoides pteronyssinus in chronic rhinitis with negative skin prick test. Asian Pac J Allergy Immunol. 24 Mar 2019.

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    2019-05-11 luwei00
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createdName=huhuaidong387, createdTime=Thu Apr 11 03:57:00 CST 2019, time=2019-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1405900, encodeId=822b1405900eb, content=<a href='/topic/show?id=a5404e589d7' target=_blank style='color:#2F92EE;'>#局部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47589, encryptionId=a5404e589d7, topicName=局部)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d14c2562456, createdName=chg122, createdTime=Thu Apr 11 03:57:00 CST 2019, time=2019-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1509846, encodeId=48a0150984659, content=<a href='/topic/show?id=8fc053e3768' target=_blank style='color:#2F92EE;'>#慢性鼻炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53737, encryptionId=8fc053e3768, topicName=慢性鼻炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6d2a10156443, createdName=fyxzlh, createdTime=Thu Apr 11 03:57:00 CST 2019, time=2019-04-11, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=2027802, encodeId=38c1202e802b3, content=<a href='/topic/show?id=72784e6449c' target=_blank style='color:#2F92EE;'>#局部过敏性鼻炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47644, encryptionId=72784e6449c, topicName=局部过敏性鼻炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d4b7363, createdName=pandamao2010, createdTime=Tue Jul 30 02:57:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1780101, encodeId=0fbd1e801019a, content=<a href='/topic/show?id=10d62860dd' target=_blank style='color:#2F92EE;'>#ASIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2860, encryptionId=10d62860dd, topicName=ASIA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e093393, createdName=luwei00, createdTime=Sat May 11 10:57:00 CST 2019, time=2019-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1956453, encodeId=7b6f1956453ad, content=<a href='/topic/show?id=b9292862f3' target=_blank style='color:#2F92EE;'>#Asian#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2862, encryptionId=b9292862f3, topicName=Asian)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKnILSXam1GxPwj04ylEzibYLFA2eGl5Ev02klt80JA0xejMPqrn0mYHNNnLEgyqYTPbicXpY3tn6SA/132, createdBy=38fd2500059, createdName=新生儿张玉军, createdTime=Sun Apr 28 21:57:00 CST 2019, time=2019-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2047099, encodeId=ea04204e099c9, content=<a href='/topic/show?id=6f5294036b1' target=_blank style='color:#2F92EE;'>#过敏性#</a>, beContent=null, 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href='/topic/show?id=bb96232801' target=_blank style='color:#2F92EE;'>#ALL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2328, encryptionId=bb96232801, topicName=ALL)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Thu Apr 11 03:57:00 CST 2019, time=2019-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1348587, encodeId=878a134858e14, content=<a href='/topic/show?id=54c24e71237' target=_blank style='color:#2F92EE;'>#屋尘螨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47712, encryptionId=54c24e71237, topicName=屋尘螨)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Thu Apr 11 03:57:00 CST 2019, time=2019-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1405900, encodeId=822b1405900eb, content=<a href='/topic/show?id=a5404e589d7' target=_blank style='color:#2F92EE;'>#局部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47589, encryptionId=a5404e589d7, topicName=局部)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d14c2562456, createdName=chg122, createdTime=Thu Apr 11 03:57:00 CST 2019, time=2019-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1509846, encodeId=48a0150984659, content=<a href='/topic/show?id=8fc053e3768' target=_blank style='color:#2F92EE;'>#慢性鼻炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53737, 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  6. [GetPortalCommentsPageByObjectIdResponse(id=2027802, encodeId=38c1202e802b3, content=<a href='/topic/show?id=72784e6449c' target=_blank style='color:#2F92EE;'>#局部过敏性鼻炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47644, encryptionId=72784e6449c, topicName=局部过敏性鼻炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d4b7363, createdName=pandamao2010, createdTime=Tue Jul 30 02:57:00 CST 2019, time=2019-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1780101, encodeId=0fbd1e801019a, content=<a href='/topic/show?id=10d62860dd' target=_blank style='color:#2F92EE;'>#ASIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2860, encryptionId=10d62860dd, topicName=ASIA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e093393, createdName=luwei00, createdTime=Sat May 11 10:57:00 CST 2019, time=2019-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1956453, encodeId=7b6f1956453ad, content=<a href='/topic/show?id=b9292862f3' target=_blank style='color:#2F92EE;'>#Asian#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2862, encryptionId=b9292862f3, topicName=Asian)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKnILSXam1GxPwj04ylEzibYLFA2eGl5Ev02klt80JA0xejMPqrn0mYHNNnLEgyqYTPbicXpY3tn6SA/132, createdBy=38fd2500059, createdName=新生儿张玉军, createdTime=Sun Apr 28 21:57:00 CST 2019, time=2019-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2047099, encodeId=ea04204e099c9, content=<a href='/topic/show?id=6f5294036b1' target=_blank style='color:#2F92EE;'>#过敏性#</a>, beContent=null, 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href='/topic/show?id=bb96232801' target=_blank style='color:#2F92EE;'>#ALL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2328, encryptionId=bb96232801, topicName=ALL)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Thu Apr 11 03:57:00 CST 2019, time=2019-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1348587, encodeId=878a134858e14, content=<a href='/topic/show?id=54c24e71237' target=_blank style='color:#2F92EE;'>#屋尘螨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47712, encryptionId=54c24e71237, topicName=屋尘螨)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Thu Apr 11 03:57:00 CST 2019, time=2019-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1405900, encodeId=822b1405900eb, content=<a href='/topic/show?id=a5404e589d7' target=_blank style='color:#2F92EE;'>#局部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47589, encryptionId=a5404e589d7, topicName=局部)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d14c2562456, createdName=chg122, createdTime=Thu Apr 11 03:57:00 CST 2019, time=2019-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1509846, encodeId=48a0150984659, content=<a href='/topic/show?id=8fc053e3768' target=_blank style='color:#2F92EE;'>#慢性鼻炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53737, encryptionId=8fc053e3768, topicName=慢性鼻炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6d2a10156443, createdName=fyxzlh, createdTime=Thu Apr 11 03:57:00 CST 2019, time=2019-04-11, status=1, ipAttribution=)]
    2019-04-11 膀胱癌
  7. 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  8. 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