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Int Forum Allergy Rhinol:血嗜酸性粒细胞能够预测慢性鼻炎患者中的射线鼻窦浑浊

2019-01-05 AlexYang MedSci原创

慢性鼻窦炎(CRS)与慢性鼻炎之间的相关性仍旧不清楚。最近,有研究人员评估了不具有CRS的慢性鼻炎患者中鼻窦浑浊的预测因素。研究人员回顾性的分析了332名患有慢性鼻炎的成年患者,他们在2015年1月到2017年12月就诊在研究人员所在单位。研究发现,总共有288名患者符合研究标准。在其中,183名(63.5%)患者为正常鼻窦组(NS),105名(36.5%)名为鼻窦浑浊组(SO)。总的免疫球蛋白E

慢性鼻窦炎(CRS)与慢性鼻炎之间的相关性仍旧不清楚。最近,有研究人员评估了不具有CRS的慢性鼻炎患者中鼻窦浑浊的预测因素。

研究人员回顾性的分析了332名患有慢性鼻炎的成年患者,他们在2015年1月到2017年12月就诊在研究人员所在单位。研究发现,总共有288名患者符合研究标准。在其中,183名(63.5%)患者为正常鼻窦组(NS),105名(36.5%)名为鼻窦浑浊组(SO)。总的免疫球蛋白E(lgE)水平和外周血嗜酸粒细胞数目在SO组中要比NS组显著更高(分别为p=0.031和P<0.0001)。研究人员利用皮尔逊相关系数分析,确定了嗜酸性粒细胞数目与LMS具有正相关关系(r = 0.282)。 在逻辑回顾分析中,嗜酸性粒细胞数目的增加与SO具有显著的相关性(OR 1.76; 95%CI, 1.30到2.39)。在调整了年龄、性别、抽烟、饮酒和潜在疾病之后,嗜酸性细胞四分位范围内数目的增加能够增加SO的风险到1.69倍,该增加是显著性的(p = 0.007; 95% CI, 1.17到2.43)。

最后,研究人员指出,外周血嗜酸性粒细胞数目是慢性鼻炎患者CRS的独立预测因子。

原始出处:

Oh SY, Hwang J, Ryu YJ et al. Blood eosinophils may predict radiographic sinus opacification in patients with chronic rhinitis. Int Forum Allergy Rhinol. 21 Dec 2018.

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