期刊： NUCLEIC ACIDS RESEARCH, 2021; 49 (12)
Initiation factor IF3 is an essential protein that enhances the fidelity and speed of bacterial mRNA translation initiation. Here, we describe the dyn......
期刊： NUCLEIC ACIDS RESEARCH, 2021; 49 (8)
Mammalian cyclic GMP-AMP synthase (cGAS) and its homologue dinucleotide cyclase in Vibrio cholerae (VcDncV) produce cyclic dinucleotides (CDNs) that p......
期刊： NUCLEIC ACIDS RESEARCH, 2021; 49 (6)
Autoactivation of two-component systems (TCSs) can increase the sensitivity to signals but inherently cause a delayed response. Here, we describe a un......
期刊： NUCLEIC ACIDS RESEARCH, 2021; 49 (W1)
With the continuing rise of lipidomic studies, there is an urgent need for a useful and comprehensive tool to facilitate lipidomic data analysis. The ......
期刊： NUCLEIC ACIDS RESEARCH, 2021; 49 (W1)
It is essential to reveal the associations between various omics data for a comprehensive understanding of the altered biological process in human wel......
期刊： NUCLEIC ACIDS RESEARCH, 2021; 49 (11)
RNA-protein interactions are central to all gene expression processes and contribute to a variety of human diseases. Therapeutic approaches targeting ......
期刊： NUCLEIC ACIDS RESEARCH, 2021; 49 (13)
Double strand break (DSB) repair primarily occurs through 3 pathways: non-homologous end-joining (NHEJ), alternative end-joining (Alt-EJ), and homolog......
期刊： NUCLEIC ACIDS RESEARCH, 2021; 49 (7)
Molecular bases of eukaryotic circadian clocks mainly rely on transcriptional-translational feedback loops (TTFLs), while epigenetic codes also play c......
期刊： NUCLEIC ACIDS RESEARCH, 2021; 49 (4)
New genetic tools and strategies are currently under development to facilitate functional genomics analyses. Here, we describe an active member of the......
期刊： NUCLEIC ACIDS RESEARCH, 2021; 49 (10)
Sequence-based analysis and prediction are fundamental bioinformatic tasks that facilitate understanding of the sequence(-structure)-function paradigm......
期刊： NUCLEIC ACIDS RESEARCH, 2021; 49 (9)
The emergence of SARS-CoV-2 infection has posed unprecedented threat to global public health. The virus-encoded non-structural protein 14 (nsp14) is a......
期刊： NUCLEIC ACIDS RESEARCH, 2021; 49 (W1)
Characterizing regulatory effects of genomic variants in plants remains a challenge. Although several tools based on deep-learning models and large-sc......
期刊： NUCLEIC ACIDS RESEARCH, 2021; 49 (7)
CRISPR-mediated gene activation (CRISPRa) is a promising therapeutic gene editing strategy without inducing DNA double-strand breaks (DSBs). However, ......
期刊： NUCLEIC ACIDS RESEARCH, 2021; 49 (5)
During oogenesis, oocytes gain competence and subsequently undergo meiotic maturation and prepare for embryonic development; trimethylated histone H3 ......
期刊： NUCLEIC ACIDS RESEARCH, 2021; 49 (W1)
In 2017, we released GEPIA (Gene Expression Profiling Interactive Analysis) webserver to facilitate the widely used analyses based on the bulk gene ex......
