期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021; 21 (11)
EGFR-TKIs are confronted with big challenge of everlasting activated EGFR mutations which lack effective binding sites; this barrier is the dark side ......
期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021; 21 (13)
The death toll associated with cancer worldwide is constantly on the increase. Efforts to combat and treat the different forms of this disease is also......
期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021; 21 (8)
Allostery is an efficient and particular regulatory mechanism to regulate protein functions. Different from conserved orthosteric sites, allosteric si......
期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021; 21 (16)
Depression is a mood disorder or affective disorder disease with depression as the main symptom. It has become a kind of mental disease that cannot be......
期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021; 21 (15)
Alzheimer's disease (AD) is a progressive neurodegenerative disease with concealed onset, which is characterized by the damage of the cholinergic syst......
期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021; 21 (11)
Benzimidazole is an aromatic bicyclic heterocycle that is regarded as a valuable privileged scaffold in medicinal chemistry. Many marketed drugs and n......
期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021; 21 (13)
Background: Metal-organic frameworks (MOFs) possess adjustable aperture, high load capacities, tailorable structures, and excellent biocompatibilities......
期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021; 21 (12)
Propolis is a natural product made from the mixture of plant resin, saliva and wax collected by bees. It has been studied and concerned because of its......
期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021; 21 (8)
As the world's population is aging, Alzheimer's disease (AD) has become a big concern since AD has started affecting younger people and the population......
期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021; 21 (9)
Azo molecules possess the characteristic azo bond (-N=N-) and are considered fascinating motifs in organic chemistry. Since the last century, these br......
期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021; 21 (15)
Oleanolic acid can inhibit edema and exhibit obvious inhibitory activity to inflammatory by activating of the pituitary-adrenal cortical system, inhib......
期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021; 21 (14)
Cholesterol, steroid alcohol, was discovered by M.E. Chevreul in 1815. Cholesterol and its derivatives showed a large variety of biological properties......
期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021; 21 (11)
As a group of heterocyclic macrocycle organic natural compounds occurring universally in animal tissues and plants, porphyrins are composed of four mo......
期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021; 21 (16)
SET protein is a multi-functional oncoprotein that is ubiquitously expressed in most tumor cells. Dysregulation of SET has been associated with many t......
期刊: MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021; 21 (15)
In recent years, marine-derived Penicillium fungi have received remarkable interest as a valuable source of novel natural products encompassing divers......