We are interested in research with likely immediate impact on clinical therapy. These include clinical studies, translational research papers addressing disease mechanism and/or therapies, biotechnology and engineering advances with important clinical impact, and resources (such as informational databases) of broad medical utility. Topics of interest for the journal include but are not limited to:

✚ Aging and health-span interventions – sarcopenia; senescence and senolytic treatments; dietary interventions; hormonal disorders
✚ Biomedical engineering; new device optimization and diagnostic tools
✚ Cancer – immuno-oncology; tumor evolution and cancer genetics; surgery and therapeutic modalities
✚ Cardiovascular and metabolic disease – heart disease; diabetes; obesity; NAFLD/NASH
✚ Genetics and cell-based therapies – medical genomics; CRISPR-based; RNAi; stem cells; organoids; transplantation
✚ Health economics and public policy – global challenges; health access; public health interventions; clinical practices
✚ Human microbiome – mechanistic studies of the human microbiome’s impact on disease
✚ Immunology – allergy and inflammation; autoimmunity; innate immunity; graft-versus host disease; vaccinology
✚ Infectious diseases – HIV/AIDS; SARS; Ebola; other bacterial, viral, fungal, or parasitic infections; infectious diseases epidemiology; antimicrobials and resistance
✚ Neurology – Alzheimer’s disease; dementia; cognitive dysfunctions; brain-vascular dysfunction; Parkinson’s and movement disorders; amyotrophic lateral sclerosis; depression; neuroengineering therapies