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Clin Oral Invest:单层和双层可吸收膜及富血小板纤维蛋白对骨愈合的影响

2018-04-26 MedSci MedSci原创

在骨吸收的重建中,一直在研究如何实现最佳的骨愈合。临床上,软组织迁移到骨吸收处是不利骨愈合的主要原因。将富含血小板的纤维蛋白,用于促进骨愈合的材料,与单层和双层可吸收胶原膜进行比较,以确定愈合方案是否可以提高患者舒适度。

在骨吸收的重建中,一直在研究如何实现最佳的骨愈合。临床上,软组织迁移到骨吸收处是不利骨愈合的主要原因。将富含血小板的纤维蛋白,用于促进骨愈合的材料,与单层和双层可吸收胶原膜进行比较,以确定愈合方案是否可以提高患者舒适度。

使用60只成年雌性Sprague-Dawley大鼠。将大鼠分成五个主要组包括处死组,对照组和三个实验组。骨缺损实验组1覆盖单层胶原膜,实验组2覆盖双层胶原膜。实验组3上覆盖处死组的富含血小板的纤维蛋白膜。以处死时间第7天和第28天,将主要组中的动物被分成八个亚组。

结果显示,实验组3中新骨形成明显高于其他组,纤维化程度低于其他组。实验组1和对照组之间没有显着差异。

与胶原膜相比,富含血小板的纤维蛋白用作促进骨愈合是可以产生更好的临床结果。

原始出处:

Mert Taysi, et al. Effects of single- and double-layered resorbable membranes and platelet-rich fibrin on bone healing.Clinical Oral Investigations. 2018 May. doi:10.1007/s00784-017-2259-z

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    2018-06-04 redcrab
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    2018-10-02 heli0118
  7. [GetPortalCommentsPageByObjectIdResponse(id=1997254, encodeId=78f5199e25475, content=<a href='/topic/show?id=cc04e727535' target=_blank style='color:#2F92EE;'>#纤维蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77275, encryptionId=cc04e727535, topicName=纤维蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0ad8182, createdName=axin009, createdTime=Mon Sep 24 12:01:00 CST 2018, time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2030875, encodeId=9a8b20308e567, content=<a href='/topic/show?id=bdf038440bb' target=_blank style='color:#2F92EE;'>#可吸收#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38440, encryptionId=bdf038440bb, topicName=可吸收)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e03212, createdName=liao1619, createdTime=Fri Jul 13 09:01:00 CST 2018, time=2018-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2026981, encodeId=60f220269819c, content=<a href='/topic/show?id=921d101668c8' target=_blank style='color:#2F92EE;'>#骨愈合#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101668, encryptionId=921d101668c8, topicName=骨愈合)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85aa264, createdName=redcrab, createdTime=Mon Jun 04 21:01:00 CST 2018, time=2018-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706224, encodeId=e5201e0622475, content=<a href='/topic/show?id=8667465e164' target=_blank style='color:#2F92EE;'>#富血小板纤维蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46571, encryptionId=8667465e164, topicName=富血小板纤维蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Mon Feb 11 21:01:00 CST 2019, time=2019-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051133, encodeId=467920511337c, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Fri Aug 03 11:01:00 CST 2018, time=2018-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020417, encodeId=af22202041eb7, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Tue Oct 02 04:01:00 CST 2018, time=2018-10-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309578, encodeId=9bc03095e8c6, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Apr 26 23:26:24 CST 2018, time=2018-04-26, status=1, ipAttribution=)]
    2018-04-26 惠映实验室

    学习了.谢谢分享.

    0

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