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BMJ:尼可地尔导致舌头溃疡——案例报道

2015-11-16 MedSci MedSci原创

82岁老年男性,他舌头的左外侧缘有如下图所示的深的痛性溃疡。溃疡出现的6个月前他因为心绞痛开始服用尼可地尔。出现口腔溃疡后患者停止服用尼可地尔,在停药后的1-5周患者溃疡和疼痛情况均得到有效改善。服用尼可地尔的人群中口腔溃疡发生率为0.4-5%。在使用尼可地尔治疗4周-36个月,溃疡可发生在任何治疗剂量情况下。关于尼可地尔导致溃疡的机制目前并不清楚。出现该类情况可以使用盐酸苄达明喷雾和口服止痛药。

82岁老年男性,他舌头的左外侧缘有如下图所示的深的痛性溃疡。



溃疡出现的6个月前他因为心绞痛开始服用尼可地尔。出现口腔溃疡后患者停止服用尼可地尔,在停药后的1-5周患者溃疡和疼痛情况均得到有效改善。

服用尼可地尔的人群中口腔溃疡发生率为0.4-5%。在使用尼可地尔治疗4周-36个月,溃疡可发生在任何治疗剂量情况下。关于尼可地尔导致溃疡的机制目前并不清楚。出现该类情况可以使用盐酸苄达明喷雾和口服止痛药。

原始出处:

Ahmed Razavi.Nicorandil induced ulcer.BMJ 2015;351:h4142

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    2016-11-08 清幽蓝燕yan

    为什么呢

    0

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    2016-08-24 flysky120

    谢谢文章

    0

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    2015-12-30 gaoxiaoe

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