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Neurology:脑室出血与尿失禁和步态障碍相关

2016-04-09 MedSci MedSci原创

目的:研究者检测脑室出血(IVH)与脑出血(ICH)幸存者3个月随访中尿失禁和步态障碍相关,这一假设。方法:出血性卒中的基因和环境危险因素研究作为发现组。脑出血种族差异研究作为重复组。对这两项研究招募的ICH病例随访3个月。多变量Logistic回归分析确定ICH后3个月尿失禁和步态障碍的危险因素。结果:研究人群包括,发现组307例脑出血患者,重复组1374例患者。在发现组,研究者发现:校正ICH

目的:研究者检测脑室出血(IVH)与脑出血(ICH)幸存者3个月随访中尿失禁和步态障碍相关,这一假设。

方法:出血性卒中的基因和环境危险因素研究作为发现组。脑出血种族差异研究作为重复组。
对这两项研究招募的ICH病例随访3个月。多变量Logistic回归分析确定ICH后3个月尿失禁和步态障碍的危险因素。

结果:研究人群包括,发现组307例脑出血患者,重复组1374例患者。在发现组,研究者发现:校正ICH位置,ICH量,年龄,基线mRS分数,性别及入院格拉斯哥昏迷量表评分后,IVH增加与尿失禁(OR 1.50;95% CI:1.10-2.06)和步态障碍(OR 1.58;95% CI 1.17-2.15)相关。在重复组,控制相同的变量后,IVH量增加也与尿失禁(OR 1.42;95% CI 1.27-1.60)和步态障碍(OR 1.40,95% CI 1.24-1.57)相关。

结论:校正与严重程度和残疾相关因素后,IVH扩大的ICH患者,发展成为尿失禁和步态障碍的风险增加。这一发现为预防或治疗IVH的ICH患者提供了一个潜在的目标。

原文出处:

Woo D, Kruger AJ, et al. Incontinence and gait disturbance after intraventricular extension of intracerebral hemorrhage. Neurology. 2016 Mar 8.

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    2016-07-10 yinhl1978
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    2016-10-12 xxxx1061
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    2016-04-14 李继凯

    文章不错

    0

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    2016-04-14 李继凯

    值得学习

    0

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    2016-04-11 tastas

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