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JCEM:中国人午睡时间与高尿酸血症风险呈正相关

2021-02-05 MedSci原创 MedSci原创

在中国人群中,较长的午睡时间(而不是夜间睡眠时间)与高尿酸血症风险独立相关。

睡眠不足或睡眠-觉醒周期紊乱与代谢障碍有关。然而,很少有研究调查每日睡眠时间与高尿酸血症之间的关系。近日,内分泌和代谢性疾病领域权威杂志Journal of Clinical Endocrinology & Metabolism上发表了一篇研究文章,该研究旨在调查每日睡眠时间(白天午睡和夜间睡眠)与高尿酸血症风险之间的关系。

研究人员对来自云南地区的中国多民族队列(CMEC)数据进行了横断面分析。在2018年,研究人员共招募了22038名年龄在30-79岁的受试者。男性血清尿酸(SUA)高于7.0 mg/dL,女性高于6.0 mg/dL定义为高尿酸血症。该研究的结局为每日睡眠时间与高尿酸血症之间的关系。

研究人员发现,白天睡眠时间与高尿酸血症的风险相关,在原始模型[OR (95%CI)为2.22 (1.88,2.61),P<0.0001]和在调整人口统计学、睡眠习惯和代谢危险因素后的多变量调整模型中[OR: 1.69;95%CI:(1.41,2.01), P<0.0001]均如此。将血清肌酐加入校正模型中,相关性有所减弱[OR:1.54;95%CI:(1.28,1.86),P<0.0001]。

较长的午睡时间也与较高的高尿酸血症合并代谢综合征(MetS)风险相关。在完全调整模型中,午睡时间超过90分钟的受访者出现高尿酸血症合并代谢综合征的风险更高[OR:1.39;95%CI:(1.06,1.79);P<0.001]。在这项研究中,研究人员没有观察到夜间睡眠时间与高尿酸血症风险之间的任何关系。

由此可见,在中国人群中,较长的午睡时间(而不是夜间睡眠时间)与高尿酸血症风险独立相关。

原始出处:

Yanjiao Wang.et al.Daytime Napping Duration is Positively Associated with Risk of Hyperuricemia in Chinese Population.JCEM.2021.https://doi.org/10.1210/clinem/dgab043

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    2021-04-29 smallant2015
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    2021-11-09 achengzhao
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    2021-09-02 zutt
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    2021-02-08 ms7000002141506965

    原来爱睡一次超过30分钟

    0

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  6. [GetPortalCommentsPageByObjectIdResponse(id=1778018, encodeId=48a61e78018c1, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Thu Apr 29 09:35:23 CST 2021, time=2021-04-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063400, encodeId=42332063400d1, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Tue Nov 09 09:35:23 CST 2021, time=2021-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1994526, encodeId=ce3d1994526c5, content=<a href='/topic/show?id=84326326141' target=_blank style='color:#2F92EE;'>#正相关#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63261, encryptionId=84326326141, topicName=正相关)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=742793, createdName=zutt, createdTime=Thu Sep 02 15:35:23 CST 2021, time=2021-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=923644, encodeId=c09992364425, content=原来爱睡一次超过30分钟, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9b355457759, createdName=ms7000002141506965, createdTime=Mon Feb 08 12:23:20 CST 2021, time=2021-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1476801, encodeId=e69614e6801f8, content=<a href='/topic/show?id=f915102342ea' target=_blank style='color:#2F92EE;'>#高尿酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102342, encryptionId=f915102342ea, topicName=高尿酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05f17331078, createdName=ms622625817193301, createdTime=Sun Feb 07 13:35:23 CST 2021, time=2021-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=923192, encodeId=6b329231927e, content=不能午睡太久了,半小时差不多, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210203/31868c6651a24ddf88f797616bd66cca/9f3ab4e993f84e8fa0d3fa23416eaf74.jpg, createdBy=addf5458457, createdName=桂枝汤不要桂枝, createdTime=Sat Feb 06 08:39:02 CST 2021, time=2021-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=923165, encodeId=6124923165a7, content=哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=969d2873055, createdName=走,走走, createdTime=Sat Feb 06 06:59:59 CST 2021, time=2021-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=923113, encodeId=5f9c923113c4, content=跟说晚上睡觉经常做梦不好一样, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e4995436242, createdName=ms2000000081813577, createdTime=Fri Feb 05 23:04:00 CST 2021, time=2021-02-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=923111, encodeId=ca2692311146, content=从来不午睡的人怎么办?, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210209/c24ce6bb97bb4de0968e69be1f6d3ca4/93f7c058bb894fc39a47081bc5283bc1.jpg, createdBy=e3945412064, createdName=Wlgank, createdTime=Fri Feb 05 22:53:19 CST 2021, time=2021-02-05, status=1, ipAttribution=)]
    2021-02-06 桂枝汤不要桂枝

    不能午睡太久了,半小时差不多

    0

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    2021-02-06 走,走走

    哈哈

    0

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    2021-02-05 ms2000000081813577

    跟说晚上睡觉经常做梦不好一样

    0

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    2021-02-05 Wlgank

    从来不午睡的人怎么办?

    0

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