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Heart:孤独、社会孤立与心血管事件之间的纵向联系

2020-05-29 MedSci原创 MedSci原创

该研究的结果为孤独与心血管事件之间的关系提供了有力的证据。在研究和预防心血管疾病的干预措施中,应将孤独视为心血管疾病的社会心理危险因素。

近日,心脏病领域权威杂志Heart上发表了一篇研究文章,研究人员旨在评估孤独症、社会孤立与心血管疾病(CVD)之间的关系,同时探究自我报告的CVD诊断和与CVD相关的住院。

该研究的数据来源于英国老年人纵向研究,这些数据与行政医院记录和死亡率登记数据相关联。用于分析自我报告CVD的分析样本量为5850,从医院记录中提取的CVD样本量为4587,随访时间长达9.6年。研究人员使用生存分析对数据进行分析,以解决竞争风险事件。

受试者平均年龄为64岁(SD为8.3)。大约44%-45%是男性。在随访过程中,有17%的参与者报告有新诊断CVD,16%的参与者有发生CVD相关的住院。研究人员发现孤独与CVD事件的风险增加相关,而与潜在的混杂因素和风险因素无关。相比于孤独感最弱的个体,孤独感最强烈的人群对CVD诊断的风险高出30%(HR为1.05,95%CI为1.01-1.09),而与CVD相关的住院人数则高出48%(HR为1.08,95%CI为1.03至1.14)。几乎没有证据表明社会隔离与CVD诊断或入院风险独立相关。

该研究的结果为孤独与心血管事件之间的关系提供了有力的证据。在研究和预防心血管疾病的干预措施中,应将孤独视为心血管疾病的社会心理危险因素。

原始出处:

Feifei Bu.et al.Longitudinal associations between loneliness, social isolation and cardiovascular events.heart.2020.https://heart.bmj.com/content/early/2020/05/26/heartjnl-2020-316614

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    2020-05-30 zhaojie88
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    2020-05-30 slcumt
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