Baidu
map

PNAS:研究减少常用药物副作用,有望药到病除

2018-02-28 佚名 Medicalxpress

澳大利亚国立大学(ANU)的最新研究已经深入到分子水平,以找到用于缓解疼痛,牙医麻醉和治疗癫痫的六种药物的相似之处,旨在寻找一种减少不必要的副作用的方法。

澳大利亚国立大学(ANU)的最新研究已经深入到分子水平,以找到用于缓解疼痛,牙医麻醉和治疗癫痫的六种药物的相似之处,旨在寻找一种减少不必要的副作用的方法。

五分之一的澳大利亚人患有慢性疼痛,25万澳大利亚人患有癫痫症,其中40%是儿童

到目前为止,研究人员已经知道,治疗疼痛和癫痫的药物是有效的,其中一些甚至自20世纪50年代以来一直用于临床。但是,由于采用了新技术,直到最近才开始研究它们如何工作以及为什么会产生副作用。

澳大利亚国立大学生物研究学院的Amanda Buyan博士表示,由于国家计算基础设施(NCI)在澳大利亚国立大学的超级计算能力,研究人员现在可以运行更大更复杂的模拟,以更好地了解发生了什么。

她说:“了解它们工作方式的分子细节,为我们提供了线索,说明为什么这些药物可能影响我们的身体,但也可能影响我们不希望影响身体的一部分。”

“理解这一点可以有希望为将来从事药物研发的科学家提供信息。”

布安博士希望这项研究能够更好地告诉科学家关于改变现有药物结构的可能性,或者设计一种新药以确保它能做到没有副作用。

“我希望这会导致药物被稍微改变,变得更加具体,或者产生更加有效的药物。”

原始出处:

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2085391, encodeId=c5a52085391e0, content=<a href='/topic/show?id=70f14863158' target=_blank style='color:#2F92EE;'>#常用药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48631, encryptionId=70f14863158, topicName=常用药物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Sat Jan 05 09:20:00 CST 2019, time=2019-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1824279, encodeId=bf0218242e9e3, content=<a href='/topic/show?id=56a932e7800' target=_blank style='color:#2F92EE;'>#副作用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32778, encryptionId=56a932e7800, topicName=副作用)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f0715, createdName=showtest, createdTime=Mon Dec 03 02:20:00 CST 2018, time=2018-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1856144, encodeId=41461856144e2, content=<a href='/topic/show?id=f32014428fc' target=_blank style='color:#2F92EE;'>#PNAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14428, encryptionId=f32014428fc, topicName=PNAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e964, createdName=drwjr, createdTime=Tue Mar 06 15:20:00 CST 2018, time=2018-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1619201, encodeId=8e82161920160, content=<a href='/topic/show?id=049148630cb' target=_blank style='color:#2F92EE;'>#常用药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48630, encryptionId=049148630cb, topicName=常用药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Fri Mar 02 12:20:00 CST 2018, time=2018-03-02, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2085391, encodeId=c5a52085391e0, content=<a href='/topic/show?id=70f14863158' target=_blank style='color:#2F92EE;'>#常用药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48631, encryptionId=70f14863158, topicName=常用药物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Sat Jan 05 09:20:00 CST 2019, time=2019-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1824279, encodeId=bf0218242e9e3, content=<a href='/topic/show?id=56a932e7800' target=_blank style='color:#2F92EE;'>#副作用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32778, encryptionId=56a932e7800, topicName=副作用)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f0715, createdName=showtest, createdTime=Mon Dec 03 02:20:00 CST 2018, time=2018-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1856144, encodeId=41461856144e2, content=<a href='/topic/show?id=f32014428fc' target=_blank style='color:#2F92EE;'>#PNAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14428, encryptionId=f32014428fc, topicName=PNAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e964, createdName=drwjr, createdTime=Tue Mar 06 15:20:00 CST 2018, time=2018-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1619201, encodeId=8e82161920160, content=<a href='/topic/show?id=049148630cb' target=_blank style='color:#2F92EE;'>#常用药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48630, encryptionId=049148630cb, topicName=常用药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Fri Mar 02 12:20:00 CST 2018, time=2018-03-02, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2085391, encodeId=c5a52085391e0, content=<a href='/topic/show?id=70f14863158' target=_blank style='color:#2F92EE;'>#常用药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48631, encryptionId=70f14863158, topicName=常用药物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Sat Jan 05 09:20:00 CST 2019, time=2019-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1824279, encodeId=bf0218242e9e3, content=<a href='/topic/show?id=56a932e7800' target=_blank style='color:#2F92EE;'>#副作用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32778, encryptionId=56a932e7800, topicName=副作用)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f0715, createdName=showtest, createdTime=Mon Dec 03 02:20:00 CST 2018, time=2018-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1856144, encodeId=41461856144e2, content=<a href='/topic/show?id=f32014428fc' target=_blank style='color:#2F92EE;'>#PNAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14428, encryptionId=f32014428fc, topicName=PNAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e964, createdName=drwjr, createdTime=Tue Mar 06 15:20:00 CST 2018, time=2018-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1619201, encodeId=8e82161920160, content=<a href='/topic/show?id=049148630cb' target=_blank style='color:#2F92EE;'>#常用药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48630, encryptionId=049148630cb, topicName=常用药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Fri Mar 02 12:20:00 CST 2018, time=2018-03-02, status=1, ipAttribution=)]
    2018-03-06 drwjr
  4. [GetPortalCommentsPageByObjectIdResponse(id=2085391, encodeId=c5a52085391e0, content=<a href='/topic/show?id=70f14863158' target=_blank style='color:#2F92EE;'>#常用药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48631, encryptionId=70f14863158, topicName=常用药物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Sat Jan 05 09:20:00 CST 2019, time=2019-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1824279, encodeId=bf0218242e9e3, content=<a href='/topic/show?id=56a932e7800' target=_blank style='color:#2F92EE;'>#副作用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32778, encryptionId=56a932e7800, topicName=副作用)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f0715, createdName=showtest, createdTime=Mon Dec 03 02:20:00 CST 2018, time=2018-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1856144, encodeId=41461856144e2, content=<a href='/topic/show?id=f32014428fc' target=_blank style='color:#2F92EE;'>#PNAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14428, encryptionId=f32014428fc, topicName=PNAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e964, createdName=drwjr, createdTime=Tue Mar 06 15:20:00 CST 2018, time=2018-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1619201, encodeId=8e82161920160, content=<a href='/topic/show?id=049148630cb' target=_blank style='color:#2F92EE;'>#常用药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48630, encryptionId=049148630cb, topicName=常用药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Fri Mar 02 12:20:00 CST 2018, time=2018-03-02, status=1, ipAttribution=)]

相关资讯

实用:常用药物禁忌一览

很多药物通用名仅一字之差,但作用则大不相同,现将部分品名易混淆、常用药物年龄限制、常用药物疾病禁忌、药过敏者禁用常用药物归纳举例如下,避免不安全用药隐患或不必要的纠纷和服务事故。 常用药物品名易混淆: 1、盐酸小檗碱片—盐酸小檗胺片 2、红霉素眼膏—红霉素软膏 3、地巴唑—他巴唑 4、强的松—可的松 5、消心痛—消炎痛 6、辅舒良—辅舒酮 7、泰利必妥眼膏—泰利必妥眼水 8、

正确吃药,时间有讲究

生病了我们要进行治疗,吃药是治病的常用方法,那么你真的会吃药么?吃药的时间,方法直接关系到药物的疗效。我们在购买药物的时候医生也会给我们一些建议,那么什么时候吃药效果好呢?下面就为大家说说吃药时间的选择!选对4个时间吃药效果最好午时预防脑出血。午时(11:00~13:00)是一天中阳气最重的时候,也是气血上冲的时候。这时有高血压的病人就不能喝酒,不能生气,也不能用重力,否则很容易得中风及出血病,比

牢记:常用药物的疾病、饮食禁忌!

1、阿奇霉素:心脏病患者慎用。 2、甲硝唑:哺乳期妇女、妊娠3个月内的孕妇、有中枢神经系统病变和血病患者禁用。 3、阿司匹林 (1)妊娠期、哺乳期妇女禁用。 (2)哮喘、鼻息肉综合症,对阿司匹林及对其他解热镇痛药过敏者禁用。 (3)血友病或血小板减少症,溃疡病活动期的患者禁用。 (4)痛风、肝肾功能减退、心功能不全、鼻出血、月经过多等患者,以及有溶血性贫血史者禁用。 4、氨咖黄敏胶囊:消化道溃

急诊值班:常用药物一览表及注意事项

1.肾上腺素 [别名]副肾素。 [药理]对α和β受体都有激动作用,使心肌收缩力加强,心率加快,心肌耗氧量增加,使皮肤粘膜及内脏小血管收缩,但冠状血管和骨骼肌血管则扩张,此外,松弛支气管和胃肠道平滑肌作用。

牢记:常用药物的疾病、饮食禁忌!

1、阿奇霉素:心脏病患者慎用。2、甲硝唑:哺乳期妇女、妊娠3个月内的孕妇、有中枢神经系统病变和血病患者禁用。3、阿司匹林(1)妊娠期、哺乳期妇女禁用。(2)哮喘、鼻息肉综合症,对阿司匹林及对其他解热镇痛药过敏者禁用。(3)血友病或血小板减少症,溃疡病活动期的患者禁用。(4)痛风、肝肾功能减退、心功能不全、鼻出血、月经过多等患者,以及有溶血性贫血史者禁用。4、氨咖黄敏胶囊:消化道溃疡患者禁用。5

Baidu
map
Baidu
map
Baidu
map