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Deep learning predicts resistance to neoadjuvant chemotherapy for locally advanced gastric cancer: a multicenter study

期刊: GASTRIC CANCER, 2022; 25 (6)

Background Accurate pre-treatment prediction of neoadjuvant chemotherapy (NACT) resistance in patients with locally advanced gastric cancer (LAGC) is ......

JIF:6.127

ADAMTS10 inhibits aggressiveness via JAK/STAT/c-MYC pathway and reprograms macrophage to create an anti-malignant microenvironment in gastric cancer

期刊: GASTRIC CANCER, 2022; 25 (6)

Background A disintegrin and metalloproteinase with thrombospondin motifs 10 (ADAMTS10) plays a role in extracellular matrix and correlates with Weill......

JIF:6.127

Hypoxia associated lncRNA HYPAL promotes proliferation of gastric cancer as ceRNA by sponging miR-431-5p to upregulate CDK14

期刊: GASTRIC CANCER, 2022; 25 (1)

Gastric cancer (GC) is a common malignant solid tumor that is characterized by high hypoxia. The transcription of genes associated with hypoxia affect......

JIF:6.127

miRNAs derived from plasma small extracellular vesicles predict organo-tropic metastasis of gastric cancer

期刊: GASTRIC CANCER, 2022; 25 (2)

Background Peritoneum, liver and lymph node are the most common metastatic sites of gastric cancer (GC). Biomarkers for GC's organo-tropic metastasis ......

JIF:6.127

Application value of overlap guiding tube (OGT) in assisting overlap esophagojejunostomy during laparoscopic total gastrectomy for gastric/gastroesophageal junction (G/GEJ) tumors

期刊: GASTRIC CANCER, 2022; 25 (4)

Background The overlap guiding tube (OGT) method, which was designed by our team to assist in overlap esophagojejunostomy, could potentially provide n......

JIF:6.127

Cancer-associated fibroblasts-derived HAPLN1 promotes tumour invasion through extracellular matrix remodeling in gastric cancer

期刊: GASTRIC CANCER, 2022; 25 (2)

Background Cancer-associated fibroblasts (CAFs) are the most principal cells of depositing and remodeling extracellular matrix (ECM) within solid tumo......

JIF:6.127

Deep learning for automatic diagnosis of gastric dysplasia using whole-slide histopathology images in endoscopic specimens

期刊: GASTRIC CANCER, 2022; 25 (4)

Background Distinguishing gastric epithelial regeneration change from dysplasia and histopathological diagnosis of dysplasia is subject to interobserv......

JIF:6.127

Risk factors for the failure of endoscopic resection of gastric submucosal tumors: a long-term retrospective case-control study

期刊: GASTRIC CANCER, 2022; 25 (5)

Objective Endoscopic resection (ER) is an effective treatment method for gastric submucosal tumors (G-SMTs), but endoscopic resection failure requires......

JIF:6.127

CAF promotes chemoresistance through NRP2 in gastric cancer

期刊: GASTRIC CANCER, 2022; 25 (3)

Background Fibroblasts are the predominant cell type in the stroma of tumor, and cancer-associated fibroblasts (CAFs) promote cancer chemoresistance b......

JIF:6.127

Convergent dysbiosis of gastric mucosa and fluid microbiome during stomach carcinogenesis

期刊: GASTRIC CANCER, 2022; 25 (5)

Background A complex microbiota in the gastric mucosa (GM) has been unveiled recently and its dysbiosis is identified to be associated with gastric ca......

JIF:6.127

Ubiquitination of ADR alpha 1d/SerpinA1 complex stimulates hypoxia to induce gastric tumorigenesis with a combination of Helicobacter pylori and chronic stress through IL-1 alpha

期刊: GASTRIC CANCER, 2022; 25 (4)

Background Helicobacter pylori (H. pylori) has been recognized as the class I carcinogen of gastric cancer and several studies have demonstrated that ......

JIF:6.127

LRG1 mediated by ATF3 promotes growth and angiogenesis of gastric cancer by regulating the SRC/STAT3/VEGFA pathway

期刊: GASTRIC CANCER, 2022; 25 (3)

Background Increasing evidence indicates that leucine-rich-alpha-2-glycoprotein 1 (LRG1) is associated with multiple malignancies, but whether it part......

JIF:6.127

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