期刊: BRITISH JOURNAL OF PHARMACOLOGY, 2021; 178 (6)
Here, we review the molecular mechanism and pharmacokinetics of flavonoids in the treatment of resistant EGF receptor (EGFR)-mutated non-small-cell lu......
期刊: BRITISH JOURNAL OF PHARMACOLOGY, 2021; 178 (18)
Background and Purpose Quercetin is a well-known plant flavonoid with neuroprotective properties. Earlier work suggested it may relieve psychiatric di......
期刊: BRITISH JOURNAL OF PHARMACOLOGY, 2021; 178 (17)
Background and Purpose Pyroptosis is a lytic form of pro-inflammatory cell death characterised as caspase 1 dependent with canonical NLRP3 inflammasom......
期刊: BRITISH JOURNAL OF PHARMACOLOGY, 2021; 178 (17)
Background and Purpose Dopamine agonists targeting D-2 receptor have been used for decades in treating pituitary adenomas. There has been little clear......
期刊: BRITISH JOURNAL OF PHARMACOLOGY, 2021; 178 (17)
Background and Purpose Anxiety disorders pose one of the biggest threats to mental health worldwide, yet current therapeutics have been mostly ineffec......
期刊: BRITISH JOURNAL OF PHARMACOLOGY, 2021; 178 (15)
Protein disulfide isomerase (PDI) is the prototypic member of the thiol isomerase family that catalyses disulfide bond rearrangement. Initially identi......
期刊: BRITISH JOURNAL OF PHARMACOLOGY, 2021; 178 (17)
Background and Purpose Liver fibrosis is one of the leading causes of morbidity and mortality worldwide but lacks any acceptable therapy. The transcri......
期刊: BRITISH JOURNAL OF PHARMACOLOGY, 2021; 178 (11)
Background and Purpose Bronchopulmonary dysplasia (BPD) is the most prevalent chronic paediatric lung disease and is linked to the development of chro......
期刊: BRITISH JOURNAL OF PHARMACOLOGY, 2021; 178 (18)
Background and Purpose Dioscin has multiple biological activities and is beneficial for cardiovascular and cerebral vascular diseases. Here, we invest......
期刊: BRITISH JOURNAL OF PHARMACOLOGY, 2021; 178 (17)
Background and Purpose: Microglia-related inflammation is associated with the pathology of Parkinson's disease. Functional voltage-gated sodium channe......
期刊: BRITISH JOURNAL OF PHARMACOLOGY, 2021; 178 (13)
Background and purpose PD-1/PD-L1 antibodies have achieved great success in clinical treatment. However, monoclonal antibody drugs also have challenge......
期刊: BRITISH JOURNAL OF PHARMACOLOGY, 2021; 178 (18)
Background and Purpose: Mineralocorticoid receptors (MRs), glucocorticoid receptors (GRs) and corticotropin-releasing factor (CRF) in the paraventricu......
期刊: BRITISH JOURNAL OF PHARMACOLOGY, 2021; 178 (12)
Background and Purpose Pancreatic cancer is an exceptionally fatal disease. However, therapeutic drugs for pancreatic cancer have presented a serious ......
期刊: BRITISH JOURNAL OF PHARMACOLOGY, 2021; 178 (15)
Background and Purpose New remedies are required for the treatment of neuropathic pain due to insufficient efficacy of available therapies. This study......
期刊: BRITISH JOURNAL OF PHARMACOLOGY, 2021; 178 (15)
Background and Purpose: Stimulation of calcium influx and suppression of autophagy play important roles in the pathogenesis of osteoarthritis (OA). In......