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Migfilin: Cell Adhesion Effect and Comorbidities

期刊: ONCOTARGETS AND THERAPY, 2022; 15 ()

Cell adhesion manifests as cell linkages to neighboring cells and/or the extracellular matrix (ECM). Migfilin is a widely expressed adhesion protein. ......

JIF:3.846

An Effective Hormonal Therapy for a Patient with Estrogen Receptor 1 (ESR1)-Amplified Metastatic Ovarian Cancer: A Case Report

期刊: ONCOTARGETS AND THERAPY, 2022; 15 ()

Hormonal therapy is an important treatment option for estrogen receptor (ER)-positive patients with advanced ovarian cancer. Although ER overexpressio......

JIF:3.846

Primary Hepatoid Adenocarcinoma of the Lung: A Systematic Literature Review

期刊: ONCOTARGETS AND THERAPY, 2022; 15 ()

Background: Hepatoid adenocarcinoma (HAC) of the lung (HAL) is a rare and aggressive extrahepatic adenocarcinoma with an unknown etiology and unfavora......

JIF:3.846

Efficacy and Safety of Pyrotinib in Human Epidermal Growth Factor Receptor 2-Positive Advanced Breast Cancer: A Multicenter, Retrospective, Real-World Study

期刊: ONCOTARGETS AND THERAPY, 2022; 15 ()

Purpose: Pyrotinib, a novel human epidermal growth factor receptor 2 (HER2)-targeted tyrosine kinase inhibitor (TKI), has led to remarkable survival o......

JIF:3.846

EGFR Mutation Status and Subtypes Predicted by CT-Based 3D Radiomic Features in Lung Adenocarcinoma

期刊: ONCOTARGETS AND THERAPY, 2022; 15 ()

Objective: In this study, we aim to establish a non-invasive tool to predict epidermal growth factor receptor (EGFR) mutation status and subtypes base......

JIF:3.846

Cetuximab and Dabrafenib Plus Trametinib for Untreated Colonic Metastasis of BRAFV600E Mutant Primary Lung Adenocarcinoma with Signet Ring Cell Features: An Interesting and Rare Case Report

期刊: ONCOTARGETS AND THERAPY, 2022; 15 ()

Colonic metastases of lung adenocarcinoma are extremely rare. Signet ring cell adenocarcinoma (SRCA) has not been described in patients with gastroint......

JIF:3.846

A Novel LOC101927967 Intergenic Region ALK Fusion Identified by NGS and Validated by IHC and FISH in a Patient with Early Stage Adenocarcinoma of Lung

期刊: ONCOTARGETS AND THERAPY, 2022; 15 ()

Anaplastic lymphoma kinase (ALK) gene rearrangement is an essential driver mutation identified in approximately 5% of non-small cell lung cancers (NSC......

JIF:3.846

Remission from the 5-Fu-Based Chemotherapy to Gemcitabine-Based Chemotherapy-Based on the Pathological Classification of Periampullary Carcinoma: A Case Report and Literature Review

期刊: ONCOTARGETS AND THERAPY, 2022; 15 ()

Background: Periampullary carcinoma, which includes ampullary carcinoma, pancreatic head cancer, distal common bile duct cancer, and duodenal papillar......

JIF:3.846

Efficacy of Disitamab Vedotin in Treating HER2 2+/FISH- Gastric Cancer

期刊: ONCOTARGETS AND THERAPY, 2022; 15 ()

Currently, effective therapies for advanced gastric cancer with systemic metastasis are lacking. Pharmacological research has been slowly progressing ......

JIF:3.846

Remarkable Response to the Triplet Combination of Olaparib with Pembrolizumab and Bevacizumab in the Third-Line Treatment of an Ovarian Clear Cell Carcinoma Patient with an ARIDIA Mutation: A Case Report

期刊: ONCOTARGETS AND THERAPY, 2022; 15 ()

Ovarian clear cell carcinoma (OCCC) is a highly aggressive malignancy with a poor prognosis, and most patients experience recurrence after primary tre......

JIF:3.846

Successful Treatment of Primary CNS Extranodal NK/T-Cell Lymphoma with Surgery and Chemotherapy Combined with Sintilimab: A Case Report and Literature Review

期刊: ONCOTARGETS AND THERAPY, 2022; 15 ()

Primary central nervous system extranodal natural killer/T-cell lymphoma (PCNS ENK/TCL) is an extremely rare lymphoma. Only 23 cases of PCNS ENK/TCL h......

JIF:3.846

Response of Scalp and Skull Metastasis to Anti-PD-1 Antibody Combined with Regorafenib Treatment in a Sorafenib-Resistant Hepatocellular Carcinoma Patient and a Literature Review

期刊: ONCOTARGETS AND THERAPY, 2022; 15 ()

Background: Scalp and skull metastasis of hepatocellular carcinoma (HCC) is extremely rare. Modalities for the treatment of this disease include crani......

JIF:3.846

Long-Term Survival of FOLFIRINOX plus toripalimab in a Patient with Metastatic Pancreatic Ductal Adenocarcinoma: A Case Report

期刊: ONCOTARGETS AND THERAPY, 2022; 15 ()

Background: Pancreatic ductal adenocarcinoma (PDAC) remains one of the most fatal diseases, with its morbidity and mortality showing an upward trend. ......

JIF:3.846

Spermidine Promotes Nb CAR-T Mediated Cytotoxicity to Lymphoma Cells Through Elevating Proliferation and Memory

期刊: ONCOTARGETS AND THERAPY, 2022; 15 ()

Purpose: Due to the natural advantages of spermidine in immunity, we investigated the effects of spermidine pretreatment on nanobody-based CAR-T cells......

JIF:3.846

Successful Treatment of Metastatic Gallbladder Carcinoma with PD-L1 Expression by the Combination of PD-1 Inhibitor Plus Bevacizumab with Chemotherapy: A Case Report

期刊: ONCOTARGETS AND THERAPY, 2022; 15 ()

Gallbladder cancer (GBC) is the most common type of biliary tract cancer. The GBC is often diagnosed at an advanced stage, which limits surgical inter......

JIF:3.846

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