期刊： CURRENT OPINION IN STRUCTURAL BIOLOGY, 2021; 67 ()
Many proteins select from a small repertoire of 3-dimensional folds retained over evolutional timescales and recruited for different functions, with c......
期刊： CURRENT OPINION IN STRUCTURAL BIOLOGY, 2021; 68 ()
The structural folds of glycosyltransferases are categorized into three superfamilies: GT-A, GT-B, and GT-C. Few structures of GT-C fold existed in th......
期刊： CURRENT OPINION IN STRUCTURAL BIOLOGY, 2021; 67 ()
Functional conformational changes of proteins can facilitate numerous biological events in cells. The Markov state model (MSM) built from molecular dy......
期刊： CURRENT OPINION IN STRUCTURAL BIOLOGY, 2021; 67 ()
Histone tails, representing the N-terminal or C-terminal regions flanking the histone core, play essential roles in chromatin signaling networks. Intr......
期刊： CURRENT OPINION IN STRUCTURAL BIOLOGY, 2020; 62 ()
Intrinsically disordered regions are often involved in allosteric regulation of multidomain proteins. They can act as disordered linkers to connect an......
期刊： CURRENT OPINION IN STRUCTURAL BIOLOGY, 2020; 62 ()
The CRISPR-Cas9 system from Streptococcus pyogenes has been exploited as a programmable RNA-guided DNA-targeting and DNA-editing platform. This evolut......
期刊： CURRENT OPINION IN STRUCTURAL BIOLOGY, 2020; 62 ()
Allostery plays important roles in many biological processes. Although all non-fibrous proteins may be allosteric, currently only a limited number of ......
期刊： CURRENT OPINION IN STRUCTURAL BIOLOGY, 2020; 62 ()
Allosteric behavior is central to the function of many proteins, enabling molecular machinery, metabolism, signaling and regulation. Recent years have......
期刊： CURRENT OPINION IN STRUCTURAL BIOLOGY, 2020; 62 ()
Protein-protein interactions involving intrinsically disordered proteins (IDPs) usually display dynamic and multivalent features. Recent experimental ......
期刊： CURRENT OPINION IN STRUCTURAL BIOLOGY, 2020; 62 ()
Chromatin mainly consists of protein and DNA, and the sequence information of DNA contributes to controlling the spatial structure of chromatin. Genom......
期刊： CURRENT OPINION IN STRUCTURAL BIOLOGY, 2020; 63 ()
G protein-coupled receptors (GPCRs) couple to diverse heterotrimeric G protein subtypes and then activate downstream signaling pathways in classical G......
期刊： CURRENT OPINION IN STRUCTURAL BIOLOGY, 2020; 63 ()
Photosystem II (PSII) catalyzes the light-driven oxygen-evolving reaction via its catalytic core and peripheral light-harvesting antennas. Oxyphototro......
期刊： CURRENT OPINION IN STRUCTURAL BIOLOGY, 2020; 63 ()
Gram-negative bacteria possess a dual-membrane envelope, which provides defense against environmental assault, as well as formidable resistance agains......
