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Serum-soluble PD-L1 may be a potential diagnostic biomarker in sepsis

期刊: SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2021; 94 (1)

To investigate whether serum-soluble PD-L1 (sPD-L1) is a potential biomarker for identifying sepsis. This study enrolled 64 septic patients, 29 patien......

Synovial fibroblasts regulate the cytotoxicity and osteoclastogenic activity of synovial natural killer cells through the RANKL-RANK axis in osteoarthritis

期刊: SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2021; 94 (2)

Chronic inflammation plays an important role in the progression of osteoarthritis (OA). Cumulative evidence suggests that natural killer (NK) cells po......

Prognostic effect of coexisting TP53 and ZFHX3 mutations in non-small cell lung cancer patients treated with immune checkpoint inhibitors

期刊: SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2021; 94 (3)

In recent years, immune checkpoint inhibitor (ICI) therapy has revolutionized the treatment of patients with advanced-stage non-small cell lung cancer......

The role of the cholinergic anti-inflammatory pathway in autoimmune rheumatic diseases

期刊: SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2021; 94 (4)

The cholinergic anti-inflammatory pathway (CAP) is a classic neuroimmune pathway, consisting of the vagus nerve, acetylcholine (ACh)-the pivotal neuro......

Summary and comparison of the perforin in teleosts and mammals: A review

期刊: SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2021; 94 (1)

Perforin, a pore-forming glycoprotein, has been demonstrated to play key roles in clearing virus-infected cells and tumour cells due to its ability of......

Dual roles of granzyme B

期刊: SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2021; 94 (3)

Granzyme B (GZMB) was first identified as a factor that could eliminate cells such as tumour cells and bacteria/virus-infected cells. However, compreh......

Regulation of thymic T regulatory cell differentiation by TECs in health and disease

期刊: SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2021; 94 (4)

The thymus produces self-limiting and self-tolerant T cells through the interaction between thymocytes and thymus epithelial cells (TECs), thereby gen......

Advances in Neutralization Assays for SARS-CoV-2

期刊: SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2021; 94 (3)

The coronavirus disease 2019 (COVID-19) pandemic has triggered a global health emergency and brought disaster to humans. Tremendous efforts have been ......

CX3CR1 might be a promising predictor of systemic lupus erythematosus patients with pulmonary fibrosis

期刊: SCANDINAVIAN JOURNAL OF IMMUNOLOGY, ; ()

The inflammatory process in systemic lupus erythematosus (SLE) affects many organs including the lungs. Chemokines are suggested to play important rol......

A bacterial stimulation assay for bronchoalveolar lavage immune cells from young children with cystic fibrosis

期刊: SCANDINAVIAN JOURNAL OF IMMUNOLOGY, ; ()

Cystic Fibrosis (CF) is primarily a progressive lung disease, characterized by chronic pulmonary infections with opportunistic pathogens. Such infecti......

PD-1-expressing MAIT cells from patients with tuberculosis exhibit elevated production of CXCL13

期刊: SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2020; 91 (4)

To understand functional role of PD-1-expressing MAIT cells during tuberculosis infection in humans, sorted PD-1(+) and PD-1(-) MAIT cells from pleura......

Mannose-capped lipoarabinomannan-induced B10 cells decrease severity of dextran sodium sulphate-induced inflammatory bowel disease in mice

期刊: SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2020; 91 (2)

Inflammatory bowel disease (IBD) is a chronic, non-specific, inflammatory gastrointestinal disease that mainly consists of Crohn's disease and ulcerat......

Hesperetin as an adjuvant augments protective anti-tumour immunity responses in B16F10 melanoma by stimulating cytotoxic CD8(+) T cells

期刊: SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2020; 91 (4)

Hesperetin (HES) is a dihydroflavone with the molecular formula of C16H14O6. It has been reported that Hesperetin has antioxidant and anticancer effec......

Cross-regulation by TLR4 and T cell Ig mucin-3 determines severity of liver injury in a CCl4-induced mouse model

期刊: SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2020; 91 (4)

Acute liver injury is a common pathological basis for a variety of acute liver diseases in the clinic, which can eventually lead to liver fibrosis and......

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