期刊： CNS NEUROSCIENCE & THERAPEUTICS, 2021; 27 (8)
Aims Glioma is a highly invasive brain tumor, which makes prognosis challenging and renders patients resistant to various treatments. Induction of cel......
期刊： CNS NEUROSCIENCE & THERAPEUTICS, 2021; 27 (9)
Background Endothelial canonical (Wnt/beta-catenin) and non-canonical Wnt signalings (Wnt/PCP and Wnt/Ca2+) promote blood-brain barrier (BBB) developm......
期刊： CNS NEUROSCIENCE & THERAPEUTICS, 2021; 27 (8)
As the organ with the highest demand for oxygen, the brain has a poor tolerance to ischemia and hypoxia. Despite severe ischemia/hypoxia induces the o......
期刊： CNS NEUROSCIENCE & THERAPEUTICS, 2021; 27 (10)
Glioma is a malignant tumor with the highest incidence among all brain tumors (about 46% of intracranial tumors) and is the most common primary intrac......
期刊： CNS NEUROSCIENCE & THERAPEUTICS, 2021; 27 (8)
Aims General anesthesia has been widely applied in surgical or nonsurgical medical procedures, but the mechanism behind remains elusive. Because of sh......
期刊： CNS NEUROSCIENCE & THERAPEUTICS, 2021; 27 (8)
Aims NOTCH3 gene mutations predominantly cause cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, a common et......
期刊： CNS NEUROSCIENCE & THERAPEUTICS, 2021; 27 (9)
Aims The blood-brain barrier (BBB) is a specialized and indispensable structure in brain blood vessels that is damaged during Alzheimer's disease (AD)......
期刊： CNS NEUROSCIENCE & THERAPEUTICS, 2021; 27 (9)
Aims: Experimental evidence demonstrated a crucial role of TROAP (Trophinin-associated protein) in regulating the cell proliferation of multiple tumor......
期刊： CNS NEUROSCIENCE & THERAPEUTICS, 2021; 27 (10)
Aim: This study aimed to investigate the regulation of pain hypersensitivity induced by the spinal synaptic transmission mechanisms underlying interle......
期刊： CNS NEUROSCIENCE & THERAPEUTICS, 2021; 27 (10)
Aims Ischemic stroke is a life-threatening disease with limited therapeutic strategies. Blood-brain barrier (BBB) disruption is a critical pathologica......
期刊： CNS NEUROSCIENCE & THERAPEUTICS, 2021; 27 (10)
Aim To demonstrate the clinical value of epithelial membrane protein 3 (EMP3) with bioinformatic analysis and clinical data, and then to establish a p......
期刊： CNS NEUROSCIENCE & THERAPEUTICS, 2021; 27 (8)
Aims High immune cell infiltration in gliomas establishes an immunosuppressive tumor microenvironment, which in turn promotes resistance to immunother......
期刊： CNS NEUROSCIENCE & THERAPEUTICS, 2021; 27 (9)
Aim Spinal cord injury (SCI) involves multiple pathological processes. Ferroptosis has been shown to play a critical role in the injury process. We wa......
期刊： CNS NEUROSCIENCE & THERAPEUTICS, 2021; 27 (10)
Aims Anti-leucine-rich glioma-inactivated 1 (LGI1) autoimmune encephalitis (AE) is characterized by complex manifestations of seizures. Here, we repor......
