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Emodin Attenuates Acetaminophen-Induced Hepatotoxicity via the cGAS-STING Pathway

期刊: INFLAMMATION, 2022; 45 (1)

Emodin is a natural bioactive compound from traditional Chinese herbs that exerts anti-inflammatory, antioxidant, anticancer, hepatoprotective, and ne......

JIF:3.55

Methyl Butyrate Alleviates Experimental Autoimmune Encephalomyelitis and Regulates the Balance of Effector T Cells and Regulatory T Cells

期刊: INFLAMMATION, 2022; 45 (3)

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS), characterized by demyelinating neuropathy. The etiology of MS is......

JIF:3.55

Expressions of Interleukin-27 in Oral Lichen Planus, Oral Leukoplakia, and Oral Squamous Cell Carcinoma

期刊: INFLAMMATION, 2022; 45 (3)

The present study aimed to detect the expression of interleukin-27 (IL-27) in tissues of oral lichen planus (OLP), oral leukoplakia (OLK), and oral sq......

JIF:3.55

IL-21 Enhances the Immune Protection Induced by the Vibrio vulnificus Hemolysin A Protein

期刊: INFLAMMATION, 2022; 45 (4)

We previously reported that the Vibrio vulnificus hemolysin A (VvhA) protein elicited good immune protection and could effectively control V. vulnific......

JIF:3.55

Therapeutic Potential of Curcumin in a Rat Model of Dextran Sulfate Sodium-Induced Ulcerative Colitis by Regulating the Balance of Treg/Th17 Cells

期刊: INFLAMMATION, 2022; 45 (6)

The pathogenesis of ulcerative colitis (UC) remains unclear, and it is believed that an imbalance of regulatory T (Treg) cells and T helper 17 (Th17) ......

JIF:3.55

Circular RNA circ_0008360 Inhibits the Proliferation, Migration, and Inflammation and Promotes Apoptosis of Fibroblast-Like Synoviocytes by Regulating miR-135b-5p/HDAC4 Axis in Rheumatoid Arthritis

期刊: INFLAMMATION, 2022; 45 (1)

Circular RNAs (circRNAs) have been demonstrated to play crucial roles in the development and progression of many diseases, including rheumatoid arthri......

JIF:3.55

Unfractionated Heparin Attenuated Histone-Induced Pulmonary Syndecan-1 Degradation in Mice: a Preliminary Study on the Roles of Heparinase Pathway

期刊: INFLAMMATION, 2022; 45 (2)

Endothelial glycocalyx degradation is thought to facilitate the development of sepsis. Histone is a significant mediator in sepsis. Unfractionated hep......

JIF:3.55

Ganoderic Acid A Attenuates IL-1 beta-Induced Inflammation in Human Nucleus Pulposus Cells Through Inhibiting the NF-kappa B Pathway

期刊: INFLAMMATION, 2022; 45 (2)

Intervertebral disc (IVD) degeneration is a major cause of low back pain associated with several pathological changes in the IVD, including dysfunctio......

JIF:3.55

Modulation of Microglia M2 Polarization and Alleviation of Hippocampal Neuron Injury By MiR-106b-5p/RGMa in a Mouse Model of Status Epilepticus

期刊: INFLAMMATION, 2022; 45 (6)

MicroRNAs (miRNAs) regulate gene expression at the post-transcriptional level. The miRNA miR-106b-5p has been linked to epilepsy, but its specific rol......

JIF:3.55

Transcription Factor Specificity Protein 1 Regulates Inflammation and Fibrin Deposition in Nasal Polyps Via the Regulation of microRNA-125b and the Wnt/beta-catenin Signaling Pathway

期刊: INFLAMMATION, 2022; 45 (3)

Nasal polyps (NPs) are multifactorial soft growths inside the nasal passages and are associated with chronic inflammation that originate from the nasa......

JIF:3.55

Evaluating the Similarity of Different Collagen-Induced Arthritis Models to the Pre-Clinical Phase of RA in Female Rats

期刊: INFLAMMATION, 2022; 45 (4)

Since the development of RA is a multistep process, it is critical to take action to prevent RA in the pre-clinical phase. Animal models are currently......

JIF:3.55

MicroRNA-98-5p Inhibits IL-13-Induced Proliferation and Migration of Human Airway Smooth Muscle Cells by Targeting RAC1

期刊: INFLAMMATION, 2022; 45 (4)

The dysfunction of airway smooth muscle cells (ASMCs) is one of the key factors in the pathogenesis of asthma. How miR-98-5p works in asthma has not b......

JIF:3.55

Sigma-1 Receptor Alleviates Airway Inflammation and Airway Remodeling Through AMPK/CXCR4 Signal Pathway

期刊: INFLAMMATION, 2022; 45 (3)

Sigma non-opioid intracellular receptor 1 (Sigma-1R) has been proven to play a major role in inflammation and structural remodeling. However, its role......

JIF:3.55

MiR-26a Reduces Inflammatory Responses via Inhibition of PGE2 Production by Targeting COX-2

期刊: INFLAMMATION, 2022; 45 (4)

MicroRNAs are small non-coding RNA regulatory molecules that play an important role in the development and function of immune cells. MicroRNA-26a (miR......

JIF:3.55

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