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雷公藤多苷/雷公藤片治疗类风湿关节炎的临床实践指南 2021

2021-01-14 Front Pharmacol . 2021 Jan 14;11:608703. doi: 10.3389/fphar.2020.608703

雷公藤(TwHF)是抗风湿性关节炎(RA)最常用和最有效的中药之一。雷公藤多甙片(TGT)和雷公藤多甙片(TWT)都是代表TwHF的代表性药物,已被纳入2019版《国家基本医疗保险,伤害保险和生育保险

中文标题:

雷公藤多苷/雷公藤片治疗类风湿关节炎的临床实践指南 2021

英文标题:

Clinical Practice Guideline for Tripterygium Glycosides/ Tripterygium wilfordii Tablets in the Treatment of Rheumatoid Arthritis

发布机构:

发布日期:

2021-01-14

简要介绍:

雷公藤(TwHF)是抗风湿性关节炎(RA)最常用和最有效的中药之一。雷公藤多甙片(TGT)和雷公藤多甙片(TWT)都是代表TwHF的代表性药物,已被纳入2019版《国家基本医疗保险,伤害保险和生育保险的医学目录》。但是,在治疗RA的过程中,患者之间的TGT / TWT反应通常存在个体差异,这意味着两种药物的临床应用可能未标准化,从而导致治疗无效和产生副作用的风险。越来越多的证据表明,TwHF的生物活性成分可能经常具有毒性,可能不会详细描述TGT和TWT的包装说明书,并且两种药物的治疗范围很窄。因此,迫切需要为TGT和TWT治疗RA制定标准化的临床实践指南。在本研究中,邀请了风湿病研究领域的一组中西医临床专家,药剂师和循证医学方法学家来选择临床问题,以确定证据水平和建议的强度,并制定建议和良好实践要点。该指南是根据临床研究证据和专家经验(循证,共识,经验补充)而形成的。由临床证据支持的临床问题可以形成建议,而没有临床证据的临床问题可以形成专家的建议。本指南中的建议和专家建议都系统地,全面地总结了TGT和TWT对RA的临床适应症,用法,剂量,联合用药和安全性,可在两种TwHF的临床应用中提供专业指导代理。

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    2023-02-25 ms5000001367546908 来自重庆

    很有意义的研究

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=2116425, encodeId=73052116425f0, content=很有意义的研究, beContent=null, objectType=guider, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d6638333665, createdName=ms5000001367546908, createdTime=Sat Feb 25 16:01:13 CST 2023, time=2023-02-25, status=1, ipAttribution=重庆), GetPortalCommentsPageByObjectIdResponse(id=1213161, encodeId=4f47121316142, content=谢谢分享, beContent=null, objectType=guider, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=67df3725267, createdName=135434d0m28暂无昵称, createdTime=Thu Apr 21 15:06:57 CST 2022, time=2022-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1212654, encodeId=1f98121265447, content=感谢分享, beContent=null, objectType=guider, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fc292854358, createdName=qqnded, createdTime=Tue Apr 19 20:41:08 CST 2022, time=2022-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1085145, encodeId=9054108514580, content=下载学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=17326410074, createdName=bjcmsp, createdTime=Tue Dec 28 17:10:12 CST 2021, time=2021-12-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1081627, encodeId=4ee9108162e74, content=没有中文版吗, beContent=null, objectType=guider, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=85ed6399099, createdName=ms3000001232289033, createdTime=Sat Dec 18 21:30:15 CST 2021, time=2021-12-18, status=1, ipAttribution=)]
    2022-04-21 135434d0m28暂无昵称

    谢谢分享

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=2116425, encodeId=73052116425f0, content=很有意义的研究, beContent=null, objectType=guider, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d6638333665, createdName=ms5000001367546908, createdTime=Sat Feb 25 16:01:13 CST 2023, time=2023-02-25, status=1, ipAttribution=重庆), GetPortalCommentsPageByObjectIdResponse(id=1213161, encodeId=4f47121316142, content=谢谢分享, beContent=null, objectType=guider, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=67df3725267, createdName=135434d0m28暂无昵称, createdTime=Thu Apr 21 15:06:57 CST 2022, time=2022-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1212654, encodeId=1f98121265447, content=感谢分享, beContent=null, objectType=guider, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fc292854358, createdName=qqnded, createdTime=Tue Apr 19 20:41:08 CST 2022, time=2022-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1085145, encodeId=9054108514580, content=下载学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=17326410074, createdName=bjcmsp, createdTime=Tue Dec 28 17:10:12 CST 2021, time=2021-12-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1081627, encodeId=4ee9108162e74, content=没有中文版吗, beContent=null, objectType=guider, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=85ed6399099, createdName=ms3000001232289033, createdTime=Sat Dec 18 21:30:15 CST 2021, time=2021-12-18, status=1, ipAttribution=)]
    2022-04-19 qqnded

    感谢分享

    0

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    2021-12-28 bjcmsp

    下载学习

    0

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    2021-12-18 ms3000001232289033

    没有中文版吗

    0

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