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非静脉曲张性上消化道出血(NVUGIH)的内窥镜诊断和处理:欧洲胃肠内窥镜学会(ESGE)指南-2021年更新。

2021-02-12 欧洲胃肠道内窥镜学会 Endoscopy. 2021 Feb 10. doi: 10.1055/a-1369-5274.

1:ESGE建议在急性上消化道出血(UGIH)患者中使用格拉斯哥-布拉奇福德评分(GBS)进行内镜检查前危险分层。 GBS≤1的患者发生再出血的风险极低,在30天内死亡,或需要医院干预,可以作为

中文标题:

非静脉曲张性上消化道出血(NVUGIH)的内窥镜诊断和处理:欧洲胃肠内窥镜学会(ESGE)指南-2021年更新。

英文标题:

Endoscopic diagnosis and management of nonvariceal upper gastrointestinal hemorrhage (NVUGIH): European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2021.

发布日期:

2021-02-12

简要介绍:

1:ESGE建议在急性上消化道出血(UGIH)患者中使用格拉斯哥-布拉奇福德评分(GBS)进行内镜检查前危险分层。 GBS≤1的患者发生再出血的风险极低,在30天内死亡,或需要医院干预,可以作为门诊内镜患者安全地进行治疗。强烈推荐,中等质量的证据。 2:ESGE建议对于小剂量阿司匹林作为继发性心血管疾病预防的单一疗法的急性UGIH患者,不应中断阿司匹林。如果由于任何原因被中断,则应尽快(最好在3-5天内)重新启动阿司匹林。强烈推荐,中等质量的证据。 3:ESGE建议在进行血流动力学复苏后,尽早(≤24小时)进行上消化道(GI)内窥镜检查。强烈推荐,高质量证据。 4:ESGE不建议紧急(≤12小时)上消化道内镜检查,因为与早期内镜检查相比,患者的预后并未得到改善。强烈推荐,高质量证据。 5:ESGE建议患有活动性溃疡(FIa,FIb)的患者,使用肾上腺素注射液联合第二种止血方式(接触热疗或机械疗法)的联合疗法。强烈推荐,高质量证据。 6:ESGE建议患有非出血性可见血管(FIIa)溃疡的患者,接触式或非接触式热疗,机械疗法或硬化剂注射,每种疗法均为单一疗法或与肾上腺素注射液配合使用。强烈推荐,高质量证据。 7:ESGE建议对于标准止血方式难以治愈的持续性出血患者,应考虑使用局部止血喷雾剂/粉剂或固定帽的夹子。推荐不力,证据质量低。 8:ESGE建议对于有反复消化性溃疡出血临床证据的患者,应考虑使用带帽的夹子。如果第二次内镜止血尝试失败,则应考虑经导管血管造影栓塞(TAE)。当TAE在本地不可用或TAE失败后,将指示手术。强烈推荐,中等质量的证据。 9:ESGE建议高剂量质子泵抑制剂(PPI)治疗用于接受内镜止血的患者以及未经内镜治疗的FIIb溃疡柱头(黏附凝块)患者。 (A):内窥镜检查后,应以静脉推注的方式给予PPI治疗,然后连续输注(例如80 mg,然后8 mg /小时),持续72小时。 (B):静脉推注(每日两次)或口服制剂(每日两次)给予的高剂量PPI治疗可以被视为替代方案。强烈推荐,高质量的证据。 10:ESGE建议在急性NVUGIH之后需要持续抗凝治疗的患者(例如消化性溃疡出血),应在控制出血后尽快恢复抗凝,最好是在出血事件后7天内或之后,基于血栓栓塞风险。与维生素K拮抗剂(VKA)相比,必须考虑直接口服抗凝剂(DOACS)的起效快。强烈推荐,低质量的证据。

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1057631, encodeId=673d105e6318a, content=👍, beContent=null, objectType=guider, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6a155600872, createdName=ms6000000298623125, createdTime=Mon Oct 04 16:32:44 CST 2021, time=2021-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1016002, encodeId=7b11101600265, content=谢谢!非常有用!, beContent=null, objectType=guider, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=03531385373, createdName=cuizhigang0085, createdTime=Thu Sep 09 11:09:30 CST 2021, time=2021-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=998692, encodeId=0e449986922c, content=谢谢,已下载, beContent=null, objectType=guider, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=32af2327351, createdName=12261e37m03暂无昵称, createdTime=Mon Jul 12 07:56:16 CST 2021, time=2021-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=968834, encodeId=95a4968834bc, content=求原文, beContent=null, objectType=guider, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=76445177887, createdName=146ee1d2m67暂无昵称, createdTime=Thu May 27 10:00:22 CST 2021, time=2021-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=948408, encodeId=5e50948408bb, content=好指南,谢谢共享, beContent=null, objectType=guider, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a00d5469352, createdName=liu77s, createdTime=Mon Mar 15 16:53:51 CST 2021, time=2021-03-15, status=1, ipAttribution=)]
    2021-10-04 ms6000000298623125

    👍

    0

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    2021-09-09 cuizhigang0085

    谢谢!非常有用!

    0

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    2021-07-12 12261e37m03暂无昵称

    谢谢,已下载

    0

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    2021-05-27 146ee1d2m67暂无昵称

    求原文

    0

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    2021-03-15 liu77s

    好指南,谢谢共享

    0

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