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帕金森病基层诊疗指南(2019年)

2020-01-30 中华医学会 中华全科医师杂志,2020,19(1):5-17.

原发性帕金森病,简称为帕金森病(Parkinson′s disease,PD)是发生于中老年人群的神经系统变性疾病,隐袭起病,进展缓慢,其特征性病理改变为黑质多巴胺能神经元进行性退变减少和

中文标题:

帕金森病基层诊疗指南(2019年)

发布机构:

中华医学会

发布日期:

2020-01-30

简要介绍:

原发性帕金森病,简称为帕金森病(Parkinson′s disease,PD)是发生于中老年人群的神经系统变性疾病,隐袭起病,进展缓慢,其特征性病理改变为黑质多巴胺能神经元进行性退变减少和路易小体形成,导致纹状体区多巴胺递质减少,从而临床上出现运动迟缓、静止性震颤、肌强直和姿势平衡障碍等特征性症状,同时伴各种非运动症状,如嗅觉障碍、便秘、睡眠障碍等。诊断主要依靠详尽的病史和完整的神经系统体格检查,尚无确诊的特异检查。

 

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评论区 (20)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2128025, encodeId=6f7e21280251d, content=太棒了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e8658407474, createdName=ms2000000826584720, createdTime=Mon Apr 24 11:43:20 CST 2023, time=2023-04-24, status=1, ipAttribution=辽宁省), GetPortalCommentsPageByObjectIdResponse(id=1188101, encodeId=a028118810105, content=用药还需要不断学习,, beContent=null, objectType=guider, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210822/d15a561e055d4cdf98b4abace82dee37/464d5f63a8dd486ab01049225a87f788.jpg, createdBy=7fa65188499, createdName=杨小屁, createdTime=Tue Jan 25 20:26:52 CST 2022, time=2022-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1183659, encodeId=0575118365936, content=学习学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211111/81c0b64745c644319545ec26d7ef0b34/9ddb2864d5df4dd9bf4305e380bffc96.jpg, createdBy=c7835705079, createdName=屋顶瞄爱赏月, createdTime=Wed Jan 12 20:56:09 CST 2022, time=2022-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1076692, encodeId=002110e669215, content=学习到了<a href='/topic/show?id=a1f9485204d' target=_blank style='color:#2F92EE;'>#帕金森病#</a>, beContent=null, objectType=guider, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48520, encryptionId=a1f9485204d, topicName=帕金森病)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210427/51a2b88526e2425097d6cfbc6159eb76/d85e25e056324556817a80a9f6d73008.jpg, createdBy=5b0a5279477, createdName=九州安错, createdTime=Sat Dec 04 00:06:55 CST 2021, time=2021-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1008389, encodeId=706810083891c, content=太棒了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ee82396893, createdName=123465c7m53暂无昵称, createdTime=Mon Aug 16 17:39:46 CST 2021, time=2021-08-16, status=1, ipAttribution=)]
    2023-04-24 ms2000000826584720 来自辽宁省

    太棒了

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=2128025, encodeId=6f7e21280251d, content=太棒了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e8658407474, createdName=ms2000000826584720, createdTime=Mon Apr 24 11:43:20 CST 2023, time=2023-04-24, status=1, ipAttribution=辽宁省), GetPortalCommentsPageByObjectIdResponse(id=1188101, encodeId=a028118810105, content=用药还需要不断学习,, beContent=null, objectType=guider, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210822/d15a561e055d4cdf98b4abace82dee37/464d5f63a8dd486ab01049225a87f788.jpg, createdBy=7fa65188499, createdName=杨小屁, createdTime=Tue Jan 25 20:26:52 CST 2022, time=2022-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1183659, encodeId=0575118365936, content=学习学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211111/81c0b64745c644319545ec26d7ef0b34/9ddb2864d5df4dd9bf4305e380bffc96.jpg, createdBy=c7835705079, createdName=屋顶瞄爱赏月, createdTime=Wed Jan 12 20:56:09 CST 2022, time=2022-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1076692, encodeId=002110e669215, content=学习到了<a href='/topic/show?id=a1f9485204d' target=_blank style='color:#2F92EE;'>#帕金森病#</a>, beContent=null, objectType=guider, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48520, encryptionId=a1f9485204d, topicName=帕金森病)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210427/51a2b88526e2425097d6cfbc6159eb76/d85e25e056324556817a80a9f6d73008.jpg, createdBy=5b0a5279477, createdName=九州安错, createdTime=Sat Dec 04 00:06:55 CST 2021, time=2021-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1008389, encodeId=706810083891c, content=太棒了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ee82396893, createdName=123465c7m53暂无昵称, createdTime=Mon Aug 16 17:39:46 CST 2021, time=2021-08-16, status=1, ipAttribution=)]
    2022-01-25 杨小屁

    用药还需要不断学习,

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=2128025, encodeId=6f7e21280251d, content=太棒了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e8658407474, createdName=ms2000000826584720, createdTime=Mon Apr 24 11:43:20 CST 2023, time=2023-04-24, status=1, ipAttribution=辽宁省), GetPortalCommentsPageByObjectIdResponse(id=1188101, encodeId=a028118810105, content=用药还需要不断学习,, beContent=null, objectType=guider, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210822/d15a561e055d4cdf98b4abace82dee37/464d5f63a8dd486ab01049225a87f788.jpg, createdBy=7fa65188499, createdName=杨小屁, createdTime=Tue Jan 25 20:26:52 CST 2022, time=2022-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1183659, encodeId=0575118365936, content=学习学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211111/81c0b64745c644319545ec26d7ef0b34/9ddb2864d5df4dd9bf4305e380bffc96.jpg, createdBy=c7835705079, createdName=屋顶瞄爱赏月, createdTime=Wed Jan 12 20:56:09 CST 2022, time=2022-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1076692, encodeId=002110e669215, content=学习到了<a href='/topic/show?id=a1f9485204d' target=_blank style='color:#2F92EE;'>#帕金森病#</a>, beContent=null, objectType=guider, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48520, encryptionId=a1f9485204d, topicName=帕金森病)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210427/51a2b88526e2425097d6cfbc6159eb76/d85e25e056324556817a80a9f6d73008.jpg, createdBy=5b0a5279477, createdName=九州安错, createdTime=Sat Dec 04 00:06:55 CST 2021, time=2021-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1008389, encodeId=706810083891c, content=太棒了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ee82396893, createdName=123465c7m53暂无昵称, createdTime=Mon Aug 16 17:39:46 CST 2021, time=2021-08-16, status=1, ipAttribution=)]
    2022-01-12 屋顶瞄爱赏月

    学习学习

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2128025, encodeId=6f7e21280251d, content=太棒了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e8658407474, createdName=ms2000000826584720, createdTime=Mon Apr 24 11:43:20 CST 2023, time=2023-04-24, status=1, ipAttribution=辽宁省), GetPortalCommentsPageByObjectIdResponse(id=1188101, encodeId=a028118810105, content=用药还需要不断学习,, beContent=null, objectType=guider, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210822/d15a561e055d4cdf98b4abace82dee37/464d5f63a8dd486ab01049225a87f788.jpg, createdBy=7fa65188499, createdName=杨小屁, createdTime=Tue Jan 25 20:26:52 CST 2022, time=2022-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1183659, encodeId=0575118365936, content=学习学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211111/81c0b64745c644319545ec26d7ef0b34/9ddb2864d5df4dd9bf4305e380bffc96.jpg, createdBy=c7835705079, createdName=屋顶瞄爱赏月, createdTime=Wed Jan 12 20:56:09 CST 2022, time=2022-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1076692, encodeId=002110e669215, content=学习到了<a href='/topic/show?id=a1f9485204d' target=_blank style='color:#2F92EE;'>#帕金森病#</a>, beContent=null, objectType=guider, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48520, encryptionId=a1f9485204d, topicName=帕金森病)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210427/51a2b88526e2425097d6cfbc6159eb76/d85e25e056324556817a80a9f6d73008.jpg, createdBy=5b0a5279477, createdName=九州安错, createdTime=Sat Dec 04 00:06:55 CST 2021, time=2021-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1008389, encodeId=706810083891c, content=太棒了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ee82396893, createdName=123465c7m53暂无昵称, createdTime=Mon Aug 16 17:39:46 CST 2021, time=2021-08-16, status=1, ipAttribution=)]
    2021-12-04 九州安错

    学习到了#帕金森病#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2128025, encodeId=6f7e21280251d, content=太棒了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e8658407474, createdName=ms2000000826584720, createdTime=Mon Apr 24 11:43:20 CST 2023, time=2023-04-24, status=1, ipAttribution=辽宁省), GetPortalCommentsPageByObjectIdResponse(id=1188101, encodeId=a028118810105, content=用药还需要不断学习,, beContent=null, objectType=guider, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210822/d15a561e055d4cdf98b4abace82dee37/464d5f63a8dd486ab01049225a87f788.jpg, createdBy=7fa65188499, createdName=杨小屁, createdTime=Tue Jan 25 20:26:52 CST 2022, time=2022-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1183659, encodeId=0575118365936, content=学习学习, beContent=null, objectType=guider, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211111/81c0b64745c644319545ec26d7ef0b34/9ddb2864d5df4dd9bf4305e380bffc96.jpg, createdBy=c7835705079, createdName=屋顶瞄爱赏月, createdTime=Wed Jan 12 20:56:09 CST 2022, time=2022-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1076692, encodeId=002110e669215, content=学习到了<a href='/topic/show?id=a1f9485204d' target=_blank style='color:#2F92EE;'>#帕金森病#</a>, beContent=null, objectType=guider, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48520, encryptionId=a1f9485204d, topicName=帕金森病)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210427/51a2b88526e2425097d6cfbc6159eb76/d85e25e056324556817a80a9f6d73008.jpg, createdBy=5b0a5279477, createdName=九州安错, createdTime=Sat Dec 04 00:06:55 CST 2021, time=2021-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1008389, encodeId=706810083891c, content=太棒了, beContent=null, objectType=guider, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ee82396893, createdName=123465c7m53暂无昵称, createdTime=Mon Aug 16 17:39:46 CST 2021, time=2021-08-16, status=1, ipAttribution=)]
    2021-08-16 123465c7m53暂无昵称

    太棒了

    0

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