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Clin Exp Rheumatol:劳动年龄类风湿性关节炎患者的虚弱性

2018-11-23 xiangting MedSci原创

即使是劳动年龄的RA患者,虚弱也很常见。

老年人群中虚弱的患病率已得到广泛研究。但是,有关劳动年龄人口的数据很少。这项研究旨在评估劳动年龄的类风湿性关节炎(RA)患者虚弱前和虚弱的患病率,并评估与虚弱前/虚弱相关的因素。在这项单中心横断面研究中,纳入了100名年龄18-65岁的RA患者。使用初级保健健康调查虚弱工具、欧洲老龄化和退休调查(SHARE-FI)来衡量虚弱性,使用临床疾病活动性指数(CDAI)衡量疾病活动性。此外,还评估了病程(年)、疼痛强度(视觉模拟量表)和就业状况。55%的患者是健壮的,30%为虚弱前,15%虚弱。虚弱前/虚弱患者中有89名承受筋疲力尽的痛苦。与健壮的个体相比,虚弱前/虚弱个体的疾病活动性评分中位数 [4.0(Q25-Q75:0-10)vs. 11(Q25-Q75:6-18)]和疼痛强度显著升高[3.0(Q25-Q75:2.0-4.0)vs. 4.0(Q25-Q75:2.8-6.3)],失业率更高[31%vs. 53%]。在多因素分析中,疾病活动性较高(β=0.444; p<0.001)、失业(β=0.243; p=0.005)、疼痛强度较高(β=0.186; p=0.060)和病程较长(β

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    2018-11-25 lmm397
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