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Neurology:心脏乳头状纤维弹性组织瘤致脑栓塞

2018-03-17 杨中华 脑血管病及重症文献导读

60岁,女性。突发左侧肢体无力。既往高血压病史。当时NIHSS 17分,平扫CT未见出血,ASPECTS 9分。当地立即给予tPA静脉溶栓,头颈CTA显示右侧MCA(M1)闭塞。立即转往我院接受血管内治疗

60岁,女性。突发左侧肢体无力。

既往高血压病史。

当时NIHSS 17分,平扫CT未见出血,ASPECTS 9分。当地立即给予tPA静脉溶栓,头颈CTA显示右侧MCA(M1)闭塞。立即转往我院接受血管内治疗。

入院MRI显示右侧基底节区梗死,头颈MRA显示右侧M1段闭塞,SWI磁敏感血管征阴性:





立即血管内治疗,并成功TICI III,取出的血栓送病理。

随后积极寻找病因,未发现动脉粥样硬化、动脉夹层、房颤的证据。经胸超声发现PFO,四肢DVT筛查阴性。各项血液检查也未见异常。

术中取出的血栓病理显示为心脏乳头状纤维弹性组织瘤(PFE)。下图分别为手术中取出的纤维弹性组织瘤的标本,以及肿瘤和乳头状结构:





随后经食道超声可见主动脉瓣漂浮的肿物,大小为1*1cm。下图分别为经胸和经食道超声:





原始出处:
Mark L. Leekoff, et al. Clinical Reasoning:An unusual cause of adult cryptogenic ischemic stroke. Neurology.2018 Feb 20;90(8):386391.doi:10.1212/WNL.0000000000004995.

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    2019-02-09 yinhl1978
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    2018-03-19 axin013
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    2018-03-18 衣带渐宽

    学习

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