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Thyroid:连续颈部超声评估妊娠期乳头状甲状腺癌的变化!

2017-06-27 xing.T MedSci原创

由此可见,在妊娠期间未观察到与PTC进展有关的临床相关变化。在积极的监测下延迟甲状腺手术对患有PTC的孕妇可能是一种合适的处理手段。

甲状腺乳头状癌(PTC)是妊娠期间诊断的常见恶性肿瘤。 然而,关于妊娠期间PTC的行为的信息很少。近日,甲状腺疾病领域权威杂志Thyroid上发表了一篇研究文章,该研究的目的是评估妊娠妇女PTC的自然发展过程。

该项研究共纳入了19例PTC患者,她们都是因为在妊娠早期或之前诊断为PTC,而推迟了甲状腺手术。使用连续颈部超声(US)来评估手术治疗前的PTC以及手术后的临床结果。

在经颈部超声进行初步诊断时最大PTC直径的中位数为0.91厘米(四分位数范围[IQR]为 0.61-1.11),19例患者中有13例(68.4%)患者有微型PTC(≤1厘米)。中位随访9.5个月后,最大PTC直径的中位数为0.98厘米(IQR为0.72-1.12)。有3例(16%)患者出现直径增加,5例(26%)患者在随访期间出现体积增加。随访期间最大肿瘤大小没有临床相关性变化(P=0.16)。在每个妊娠阶段连续颈部超声数据可用的七名妊娠妇女中,研究人员发现不同妊娠阶段之间PTC的大小指标没有显著性差异(妊娠早期 vs. 妊娠中期,P=0.81;妊娠中期 vs. 妊娠晚期 P=0.99)。随访期间,颈部超声并未发现甲状腺或颈淋巴结发生新的病变。在19例患者中,16例患者在分娩后进行了甲状腺手术,从诊断到手术的时间中位数为11.9个月。

由此可见,在妊娠期间未观察到与PTC进展有关的临床相关变化。在积极的监测下延迟甲状腺手术对患有PTC的孕妇可能是一种合适的处理手段。
 
原始出处:
 

Hye-Seon Oh,et al. Serial Neck Ultrasonographic Evaluation of Changes in Papillary Thyroid Carcinoma During Pregnancy. Thyroid. http://online.liebertpub.com/doi/abs/10.1089/thy.2016.0618

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    2017-06-27 1dd8aa01m06(暂无匿称)

    学习了很好的内容

    0

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    2017-06-27 1dd8aa01m06(暂无匿称)

    学习了很好的内容

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2040445, encodeId=bff920404459d, content=<a href='/topic/show?id=e2f523589f3' target=_blank style='color:#2F92EE;'>#乳头状甲状腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23589, encryptionId=e2f523589f3, topicName=乳头状甲状腺癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=991e83, createdName=wincls, createdTime=Sat Mar 31 12:29:00 CST 2018, time=2018-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044978, encodeId=59c320449e8e1, content=<a href='/topic/show?id=a4d02358610' target=_blank style='color:#2F92EE;'>#乳头状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23586, encryptionId=a4d02358610, topicName=乳头状)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce5632, createdName=jianjun66, createdTime=Sat Mar 03 05:29:00 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2080025, encodeId=b1b920800255d, content=<a href='/topic/show?id=38879282433' target=_blank style='color:#2F92EE;'>#超声评估#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92824, encryptionId=38879282433, topicName=超声评估)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f9279, createdName=slcumt, createdTime=Mon Jul 17 15:29:00 CST 2017, time=2017-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1251050, encodeId=f43e1251050f4, content=<a href='/topic/show?id=90494486837' target=_blank style='color:#2F92EE;'>#妊娠期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44868, encryptionId=90494486837, topicName=妊娠期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Wed Jun 28 23:29:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1589719, encodeId=27561589e1911, content=<a href='/topic/show?id=124d10065220' target=_blank style='color:#2F92EE;'>#颈部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100652, encryptionId=124d10065220, topicName=颈部)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c46a17776631, createdName=木头人519, createdTime=Wed Jun 28 23:29:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215990, encodeId=7a3c215990a4, content=学习了很好的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Tue Jun 27 14:08:04 CST 2017, time=2017-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215987, encodeId=73ce21598e81, content=学习了很好的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Tue Jun 27 14:04:24 CST 2017, time=2017-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215923, encodeId=d4e5215923d9, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Tue Jun 27 10:04:12 CST 2017, time=2017-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215899, encodeId=bab9215899a2, content=很好, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2emBzjO0FtqTJ05AqrEEdRmp6tmlsLXqpzfxWdtgbbgPGWRHagoK9fLTd3IayRPgkJVIVBWtdlmnkBhOIR4cFM/0, createdBy=e8d51649330, createdName=飘飘爱, createdTime=Tue Jun 27 08:39:23 CST 2017, time=2017-06-27, status=1, ipAttribution=)]
    2017-06-27 jacob9231

    学习了谢谢分享

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=2040445, encodeId=bff920404459d, content=<a href='/topic/show?id=e2f523589f3' target=_blank style='color:#2F92EE;'>#乳头状甲状腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23589, encryptionId=e2f523589f3, topicName=乳头状甲状腺癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=991e83, createdName=wincls, createdTime=Sat Mar 31 12:29:00 CST 2018, time=2018-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2044978, encodeId=59c320449e8e1, content=<a href='/topic/show?id=a4d02358610' target=_blank style='color:#2F92EE;'>#乳头状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23586, encryptionId=a4d02358610, topicName=乳头状)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce5632, createdName=jianjun66, createdTime=Sat Mar 03 05:29:00 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2080025, encodeId=b1b920800255d, content=<a href='/topic/show?id=38879282433' target=_blank style='color:#2F92EE;'>#超声评估#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92824, encryptionId=38879282433, topicName=超声评估)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f9279, createdName=slcumt, createdTime=Mon Jul 17 15:29:00 CST 2017, time=2017-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1251050, encodeId=f43e1251050f4, content=<a href='/topic/show?id=90494486837' target=_blank style='color:#2F92EE;'>#妊娠期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44868, encryptionId=90494486837, topicName=妊娠期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0b7c20, createdName=wjcjjian, createdTime=Wed Jun 28 23:29:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1589719, encodeId=27561589e1911, content=<a href='/topic/show?id=124d10065220' target=_blank style='color:#2F92EE;'>#颈部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100652, encryptionId=124d10065220, topicName=颈部)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c46a17776631, createdName=木头人519, createdTime=Wed Jun 28 23:29:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215990, encodeId=7a3c215990a4, content=学习了很好的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Tue Jun 27 14:08:04 CST 2017, time=2017-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215987, encodeId=73ce21598e81, content=学习了很好的内容, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Tue Jun 27 14:04:24 CST 2017, time=2017-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215923, encodeId=d4e5215923d9, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Tue Jun 27 10:04:12 CST 2017, time=2017-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215899, encodeId=bab9215899a2, content=很好, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2emBzjO0FtqTJ05AqrEEdRmp6tmlsLXqpzfxWdtgbbgPGWRHagoK9fLTd3IayRPgkJVIVBWtdlmnkBhOIR4cFM/0, createdBy=e8d51649330, createdName=飘飘爱, createdTime=Tue Jun 27 08:39:23 CST 2017, time=2017-06-27, status=1, ipAttribution=)]
    2017-06-27 飘飘爱

    很好

    0

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