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NEJM:肺炎克雷伯菌感染所致的前房积脓

2016-06-30 MedSci MedSci原创

患者男性,49岁,因全身虚弱9天而入院检查肌酐,肝酶和胆红素水平的升高情况,住院3天后出现右眼视物模糊。患者存在糖尿病病史。曾因肺炎克雷伯菌感染导致的双侧肾皮质脓肿而引起的菌血症接受治疗。检查显示,其右眼视力为“光感”。裂隙灯检查发现存在前房积脓(白细胞聚集在前房)(图A,箭头),虹膜后粘连(虹膜与晶状体粘连)(图B和C,箭;破裂粘连处位于在六点钟方向),且有纤维素性渗出物覆盖在晶状体前囊膜(图B

患者男性,49岁,因全身虚弱9天而入院检查肌酐,肝酶和胆红素水平的升高情况,住院3天后出现右眼视物模糊。

患者存在糖尿病病史。曾因肺炎克雷伯菌感染导致的双侧肾皮质脓肿而引起的菌血症接受治疗。

检查显示,其右眼视力为“光感”。裂隙灯检查发现存在前房积脓(白细胞聚集在前房)(图A,箭头),虹膜后粘连(虹膜与晶状体粘连)(图B和C,箭;破裂粘连处位于在六点钟方向),且有纤维素性渗出物覆盖在晶状体前囊膜(图B和C,箭头所示)。眼底镜检查可见致密的玻璃体。



这些检查结果提示为内源性眼内炎。治疗后炎症消退,但是伴有玻璃体浓缩。B超检查显示牵引性视网膜脱离,行玻璃体切除联合硅油注入术。

在10周的随访期间,右眼的视力提高到4 / 200。肺炎克雷伯菌是引起内源性眼内炎的一种罕见但是很严重的致病菌,特别是在亚洲的糖尿病患者中,通常与原发性肝脓肿相关。视力检查和早期抗生素治疗是决定疾病结局的重要决定因素。

原始出处:

Osama M. Mustafa, M.B., B.S.Patricio M. Aduriz-Lorenzo, M.D. Hypopyon and Klebsiella Sepsis. N Engl J Med 2016; 374:e33June 30, 2016DOI: 10.1056/NEJMicm1509932.

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  1. [GetPortalCommentsPageByObjectIdResponse(id=2065898, encodeId=d06f2065898e8, content=<a href='/topic/show?id=ee358216611' target=_blank style='color:#2F92EE;'>#肺炎克雷伯菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82166, encryptionId=ee358216611, topicName=肺炎克雷伯菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05a2499, createdName=dzx0922889, createdTime=Sun Apr 16 00:58:00 CST 2017, time=2017-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=126723, encodeId=999b126e23cf, content=文章不错,值得拜读, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 14 14:49:00 CST 2016, time=2016-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=94810, encodeId=1cc79481069, content=学习了。不错的案例, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160726/IMG57976A6F5B33B3316.jpg, createdBy=f7231677766, createdName=吧唧吧唧, createdTime=Wed Jul 27 00:55:00 CST 2016, time=2016-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91942, encodeId=c68e91942fc, content=不错的案例,又分析了肺克所致罕见的临床症状, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170701/IMG595791009FB761316.jpg, createdBy=abd01695121, createdName=吴教授, createdTime=Tue Jul 05 07:04:00 CST 2016, time=2016-07-05, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2065898, encodeId=d06f2065898e8, content=<a href='/topic/show?id=ee358216611' target=_blank style='color:#2F92EE;'>#肺炎克雷伯菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82166, encryptionId=ee358216611, topicName=肺炎克雷伯菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05a2499, createdName=dzx0922889, createdTime=Sun Apr 16 00:58:00 CST 2017, time=2017-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=126723, encodeId=999b126e23cf, content=文章不错,值得拜读, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 14 14:49:00 CST 2016, time=2016-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=94810, encodeId=1cc79481069, content=学习了。不错的案例, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160726/IMG57976A6F5B33B3316.jpg, createdBy=f7231677766, createdName=吧唧吧唧, createdTime=Wed Jul 27 00:55:00 CST 2016, time=2016-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91942, encodeId=c68e91942fc, content=不错的案例,又分析了肺克所致罕见的临床症状, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170701/IMG595791009FB761316.jpg, createdBy=abd01695121, createdName=吴教授, createdTime=Tue Jul 05 07:04:00 CST 2016, time=2016-07-05, status=1, ipAttribution=)]
    2016-09-14 1e10c84am36(暂无匿称)

    文章不错,值得拜读

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=2065898, encodeId=d06f2065898e8, content=<a href='/topic/show?id=ee358216611' target=_blank style='color:#2F92EE;'>#肺炎克雷伯菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82166, encryptionId=ee358216611, topicName=肺炎克雷伯菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05a2499, createdName=dzx0922889, createdTime=Sun Apr 16 00:58:00 CST 2017, time=2017-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=126723, encodeId=999b126e23cf, content=文章不错,值得拜读, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 14 14:49:00 CST 2016, time=2016-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=94810, encodeId=1cc79481069, content=学习了。不错的案例, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160726/IMG57976A6F5B33B3316.jpg, createdBy=f7231677766, createdName=吧唧吧唧, createdTime=Wed Jul 27 00:55:00 CST 2016, time=2016-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91942, encodeId=c68e91942fc, content=不错的案例,又分析了肺克所致罕见的临床症状, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170701/IMG595791009FB761316.jpg, createdBy=abd01695121, createdName=吴教授, createdTime=Tue Jul 05 07:04:00 CST 2016, time=2016-07-05, status=1, ipAttribution=)]
    2016-07-27 吧唧吧唧

    学习了。不错的案例

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2065898, encodeId=d06f2065898e8, content=<a href='/topic/show?id=ee358216611' target=_blank style='color:#2F92EE;'>#肺炎克雷伯菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82166, encryptionId=ee358216611, topicName=肺炎克雷伯菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05a2499, createdName=dzx0922889, createdTime=Sun Apr 16 00:58:00 CST 2017, time=2017-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=126723, encodeId=999b126e23cf, content=文章不错,值得拜读, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 14 14:49:00 CST 2016, time=2016-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=94810, encodeId=1cc79481069, content=学习了。不错的案例, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160726/IMG57976A6F5B33B3316.jpg, createdBy=f7231677766, createdName=吧唧吧唧, createdTime=Wed Jul 27 00:55:00 CST 2016, time=2016-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=91942, encodeId=c68e91942fc, content=不错的案例,又分析了肺克所致罕见的临床症状, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170701/IMG595791009FB761316.jpg, createdBy=abd01695121, createdName=吴教授, createdTime=Tue Jul 05 07:04:00 CST 2016, time=2016-07-05, status=1, ipAttribution=)]
    2016-07-05 吴教授

    不错的案例,又分析了肺克所致罕见的临床症状

    0

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