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AJG:糖尿病胃轻瘫患者延迟胃排空与糖尿病并发症的关系

2019-11-30 不详 MedSci原创

1型糖尿病(T1DM)患者的糖尿病出现d胃轻瘫(Gp)的发生率高于2型糖尿病(T2DM)患者。本项研究旨在评估患有Gp症状的糖尿病患者的糖尿病并发症(视网膜病变,肾病和周围神经病变)的患病率,并评估了T1DM和T2DM与延迟和正常胃排空(GE)之间的差异。

目的:
1型糖尿病(T1DM)患者的糖尿病出现d轻瘫(Gp)的发生率高于2型糖尿病(T2DM)患者。本项研究旨在评估患有Gp症状的糖尿病患者的糖尿病并发症(视网膜病变,肾病和周围神经病变)的患病率,并评估了T1DM和T2DM与延迟和正常排空(GE)之间的差异。

方法:
研究人员对有Gp症状的糖尿病患者进行病史和体格检查,自主神经功能检查以及评估症状和填写了周围神经病变的问卷。

结果:
本项研究共纳入了133名患有Gp症状的糖尿病患者:59名T1DM患者,74名T2DM患者,103名GE延迟患者和30名GE延迟患者。T2DM患者中的视网膜病变(37%vs 24%; P = 0.13),肾病(19%vs 11%; P = 0.22)和周围神经病变(53%vs 39%; P = 0.16)的存在并不显着高于T1DM患者;但是,在10%的T1DM和3%的T2DM中发现了三病(共3种并发症)(P = 0.04)。延迟GE的糖尿病患者视网膜病变患病率增加(36%vs 10%; P = 0.006)和糖尿病并发症发生率增加(1.0 vs 0.5; P= 0.009);但是,有39%的出现dGE延迟的糖尿病患者没有任何糖尿病并发症。

讨论:
在患有Gp症状的糖尿病患者中,GE延迟与视网膜病变的存在和糖尿病并发症的总数有关。

原始出处:

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    2020-10-14 贵阳
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    2020-02-02 丁鹏鹏
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    2020-07-23 minzju5052
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    2019-11-30 misszhang

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