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结核检查结果全阴性,医生竟然也让孩子吃了三个月抗结核药

2017-03-26 甘路民 湖南省儿童医院

2017年3月24日是结核病日,今年的主题是:联合起来消除结核,不让任何人掉队。案例一近日,儿童医院感染科门诊来了一个情绪激动的年轻父母,他们痛斥医生乱开药,说孩子检查显示没有结核病,医生竟然给孩子吃了3个月抗结核药,这不是乱开药么?感染科刘静主任耐心的接待了这对年轻的父母。原来欢欢是个留守儿童,不久前,一直照顾她的外婆被查出患有开放性肺结核,当地医生建议欢欢也检查一下,以免被传染;外婆带欢欢来到

2017年3月24日是结核病日,今年的主题是:联合起来消除结核,不让任何人掉队。

案例一

近日,儿童医院感染科门诊来了一个情绪激动的年轻父母,他们痛斥医生乱开药,说孩子检查显示没有结核病,医生竟然给孩子吃了3个月抗结核药,这不是乱开药么?

感染科刘静主任耐心的接待了这对年轻的父母。原来欢欢是个留守儿童,不久前,一直照顾她的外婆被查出患有开放性肺结核,当地医生建议欢欢也检查一下,以免被传染;外婆带欢欢来到儿童医院,检查确实没有提示欢欢患有结核,但感染科医生仍建议给欢欢预防性的服用3个月抗结核的药,因为外婆年纪大,没有记清楚医生说明的用药原因,就也跟孩子父母说不清...

刘静主任耐心的解释了欢欢用药的目的:与开放性肺结核成人有接触的儿童,即使检查提示没有被感染结核,也需要预防性服用抗结核药。 因为结核菌感染后需4—8周才能建立充分变态反应,在该变态反应产生之前,检查可以无异常:结核菌素试验可呈阴性,胸片无改变。

也就是说,与开放性肺结核成人密切接触的儿童均为高危人群,应定期检查和随访,秉着结核早期治疗的原则,如果结核菌素皮试阴性,即使无任何症状和X线检查异常,也应预防性服用异烟肼3个月,再复查结核菌素皮试,如果仍为阴性,可停止治疗;如果皮试转为阳性,则按结核感染治疗6-9个月。

最后欢欢的父母表示理解,并愿意配合医生治疗...

案例二

去年,小强的舅舅查出了传染性肺结核,在进行密切接触者筛查时,小强结核菌素(即PPD)皮肤试验强阳性,表明小强已经感染结核菌,医生建议应用预防性抗结核治疗。小强母亲觉得孩子并没有结核病症状,加上担心药物的副作用,不同意预防性治疗。3个月后,小强出现发烧的症状,体温达39℃,又过2天后呼吸困难,最后被确诊为结核性胸膜炎...直到进行规律性抗结核治疗后小强的病情好转。

刘静主任说:临床中会碰到很多这种情况,身边密切接触的人被查出传染性结核,在没查出结核感染的证据前,大部分家长觉得孩子并没有结核病症状,加上担心药物的副作用,不同意预防性治疗而错过治疗最佳时期。

由于儿童期免疫系统处于逐渐成熟的过程,结核病发生时相对成年人严重,因此呼吁家长,对于与结核病患者密切接触的儿童需高度关注。而且,孩子结核感染后症状表现不典型,也与成人不同,孩子如果有下面这些表现要警惕结核病:

结核病患者的家庭人员或与其密切接触者

母乳喂养孩子的母亲患开放性肺结核;

长期干咳、气促、声音嘶哑等呼吸道症状;

不明原因持续性的中低度发热;

出现消化不良、食欲减退;

儿童出现易哭闹、精神不振、睡眠不佳等症状;

睡着后大量出汗,尤其是午睡过后;

出现不明原因的体重下降。

关于结核,家长有最关心的话题答疑

打了卡介苗就还会得结核吗?

患有结核是不是因为卡介苗没接种成功?

医生:卡介苗是用已退化了毒性的结核杆菌注射到人体中,从而使人体产生免疫力。不过,打了这个疫苗,预防的是血型播散型结核,减少的是结核性脑膜炎的发病率,目的是使结核的破坏力限制在局部,不对人体产生太大危害。

结核病不是早已经消灭了吗?

医生:在抗结核药物出现之前,结核病属于“不治之症”,发现了抗结核病药,并普及了各种防控措施,结核病明显减少;20世纪80年代中期起,由于耐药结核菌的产生、艾滋病人增多、移民等原因,结核病又卷土重来,目前结核病并不少见。

近几年官方数据显示:我国结核病年发病人数约130万,占全球发病人数的14.3%,位居全球第2位,是全球22个结核病流行严重的国家之一,同时也是全球27个耐多药结核病流行严重的国家之一。只是因为卡介苗的普及,我们结核的重症已经显着减少。

怎样做可以有效预防结核?

医生: 预防肺结核关键是提高免疫力 。其实结核菌的感染率很高,如果做个化验,50%的人应该都感染过。只是因为体质不同,有的人感染后会发病,有的人不会发病。这其中,免疫力的强弱起到比较重要的作用。

因为结核杆菌进入人体后,免疫系统会马上将其消灭,如果免疫力下降,没法把病菌全部消灭,病菌阵营就会壮大,甚至诱发疾病,比如受过结核菌感染而未发病的小儿,在患其他急性传染病时抵抗力急剧下降,则容易出现结核病活化。

另外,结核病菌是经飞沫传播的,因此要注意密闭的大型公共场所及公共交通工具,在人流较多及空气不流通的地方,最好戴上口罩,以免传染。

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encryptionId=f30ae86297d, topicName=结核)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Tue Mar 28 12:22:00 CST 2017, time=2017-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=183124, encodeId=8b5118312428, content=沟通和病人依从性有关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Mon Mar 27 23:31:42 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=183045, encodeId=cb0b18304569, content=欠缺医患沟通,和老人沟通起来困难一些, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Mon Mar 27 11:21:26 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=183020, encodeId=e12c1830202d, content=文章不错,值得分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Mon Mar 27 09:00:30 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=183009, encodeId=d9621830097b, content=好好学习,涨知识, 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GetPortalCommentsPageByObjectIdResponse(id=182980, encodeId=147a1829802a, content=医学科普宣传教育任重道远, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/udqvoAsWtvRVficPKOpMh4M31O9bJ8jMiaUHAheeNpIqMapC8mUnBWfEskrcVjofbicWU4icRD6vFvVeEYlPmSbXELickazEGVFYO/0, createdBy=24741603767, createdName=医艺依意, createdTime=Mon Mar 27 07:40:58 CST 2017, time=2017-03-27, status=1, ipAttribution=)]
    2017-03-28 wgx309
  4. 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  5. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Mon Mar 27 08:32:05 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=183001, encodeId=b10918300143, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Mon Mar 27 08:20:43 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182980, encodeId=147a1829802a, content=医学科普宣传教育任重道远, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/udqvoAsWtvRVficPKOpMh4M31O9bJ8jMiaUHAheeNpIqMapC8mUnBWfEskrcVjofbicWU4icRD6vFvVeEYlPmSbXELickazEGVFYO/0, createdBy=24741603767, createdName=医艺依意, createdTime=Mon Mar 27 07:40:58 CST 2017, time=2017-03-27, status=1, ipAttribution=)]
    2017-03-27 cqykthl

    沟通和病人依从性有关。

    0

  6. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Mon Mar 27 11:21:26 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=183020, encodeId=e12c1830202d, content=文章不错,值得分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Mon Mar 27 09:00:30 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=183009, encodeId=d9621830097b, content=好好学习,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Mon Mar 27 08:32:05 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=183001, encodeId=b10918300143, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Mon Mar 27 08:20:43 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182980, encodeId=147a1829802a, content=医学科普宣传教育任重道远, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/udqvoAsWtvRVficPKOpMh4M31O9bJ8jMiaUHAheeNpIqMapC8mUnBWfEskrcVjofbicWU4icRD6vFvVeEYlPmSbXELickazEGVFYO/0, createdBy=24741603767, createdName=医艺依意, createdTime=Mon Mar 27 07:40:58 CST 2017, time=2017-03-27, status=1, ipAttribution=)]
    2017-03-27 有备才能无患

    欠缺医患沟通,和老人沟通起来困难一些

    0

  7. 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encryptionId=f30ae86297d, topicName=结核)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Tue Mar 28 12:22:00 CST 2017, time=2017-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=183124, encodeId=8b5118312428, content=沟通和病人依从性有关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdicLmdJEK9VoiaDianY6fzHNN9iaGv80m39pMHU3eSnNN0kn1o0rdQ7Bz2f03Qibcf1ia7rKvxIt4UVlErF2d4gCmDC5/0, createdBy=98e31740255, createdName=cqykthl, createdTime=Mon Mar 27 23:31:42 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=183045, encodeId=cb0b18304569, content=欠缺医患沟通,和老人沟通起来困难一些, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Mon Mar 27 08:32:05 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=183001, encodeId=b10918300143, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Mon Mar 27 08:20:43 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182980, encodeId=147a1829802a, content=医学科普宣传教育任重道远, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/udqvoAsWtvRVficPKOpMh4M31O9bJ8jMiaUHAheeNpIqMapC8mUnBWfEskrcVjofbicWU4icRD6vFvVeEYlPmSbXELickazEGVFYO/0, createdBy=24741603767, createdName=医艺依意, createdTime=Mon Mar 27 07:40:58 CST 2017, time=2017-03-27, status=1, ipAttribution=)]
    2017-03-27 1e10c84am36(暂无匿称)

    文章不错,值得分享

    0

  8. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Mon Mar 27 08:32:05 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=183001, encodeId=b10918300143, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Mon Mar 27 08:20:43 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182980, encodeId=147a1829802a, content=医学科普宣传教育任重道远, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/udqvoAsWtvRVficPKOpMh4M31O9bJ8jMiaUHAheeNpIqMapC8mUnBWfEskrcVjofbicWU4icRD6vFvVeEYlPmSbXELickazEGVFYO/0, createdBy=24741603767, createdName=医艺依意, createdTime=Mon Mar 27 07:40:58 CST 2017, time=2017-03-27, status=1, ipAttribution=)]
    2017-03-27 shaosai

    好好学习,涨知识

    0

  9. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Mon Mar 27 11:21:26 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=183020, encodeId=e12c1830202d, content=文章不错,值得分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Mon Mar 27 09:00:30 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=183009, encodeId=d9621830097b, content=好好学习,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Mon Mar 27 08:32:05 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=183001, encodeId=b10918300143, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Mon Mar 27 08:20:43 CST 2017, time=2017-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182980, encodeId=147a1829802a, content=医学科普宣传教育任重道远, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/udqvoAsWtvRVficPKOpMh4M31O9bJ8jMiaUHAheeNpIqMapC8mUnBWfEskrcVjofbicWU4icRD6vFvVeEYlPmSbXELickazEGVFYO/0, createdBy=24741603767, createdName=医艺依意, createdTime=Mon Mar 27 07:40:58 CST 2017, time=2017-03-27, status=1, ipAttribution=)]
    2017-03-27 明月清辉

    谢谢分享,学习了

    0

  10. 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    2017-03-27 医艺依意

    医学科普宣传教育任重道远

    0

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