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Gastroenterology:89%的结肠镜检查后结直肠癌或可避免

2020-04-20 MedSci原创 MedSci原创

近九成的结肠镜检查后结直肠癌是可以避免的

结肠镜检查后结直肠癌(PCCRC)是在结肠镜检查时未发现癌细胞,而后诊断为CRC。近日研究人员对PCCRC的病例和相关因素进行考察,量化可避免的PCCRC的比例。
 
研究人员对2010年1月1日至2017年12月31日在英国的一个单一医疗中心中107例PCCRC患者数据进行了回顾性分析。对于每一例,研究人员都回顾了临床,病理,放射学和内镜检查结果。根据世界内镜检查组织(WEO)的建议,研究人员对每个病例进行了根本原因分析,将病变分类如下:可能遗漏的病变,事先检查充足;可能的漏诊病变,事先检查不足;发现病变,未切除;或先前确定的病变可能未完全切除。根据WEO肿瘤的分类和大小,我们确定了PCCRC是否可以归因于结肠镜检查者的技术或决策原因,以及PCCRC是否可以避免。
 
在已确定的PCCRC中,43%是高危患者(已患有炎症性肠病、既往CRC、既往多发性息肉或遗传性癌症综合征),66%位于肝弯曲远端。结肠镜检查后结直肠肿瘤大小、指数与结肠镜检查后诊断时间无相关性。在19%的结肠镜检查中,肠道准备不良,只有36%的结肠镜检查有足够的光照完成。73%的PCCRC被确定为受技术内镜因素的影响,17%的PCCRC受管理因素的影响,27%的PCCRC受决策因素的影响。27%的PCCRC被归类为可能的漏诊病变,先前的检查是足够的;58%的PCCRC可能漏诊病变,先前的检查是不充分的;8%为检测到病变,没有切除;7%为先前观察到的病变未完全切除。89%PCCRC被认为是可以避免的。
 
研究认为,近九成的结肠镜检查后结直肠癌是可以避免的。
 
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    2020-07-02 许安
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    2020-04-22 zhouqu_8
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    2020-04-21 常春藤0702

    好好

    0

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    2020-04-21 thm112988

    0

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