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NEJM:利用脐带血治疗白血病显神效

2016-09-14 佚名 生物谷

日前,一项刊登在国际杂志New England Journal of Medicine的题为“Cord-Blood Transplantation in Patients with Minimal Residual Disease”的研究报告中,来自福瑞德哈金森肿瘤研究中心的研究人员通过研究表示,脐带血或许可以作为治疗成人和儿童白血病的优选方案,甚至在有些病例治疗过程中脐带血治疗还能够带来较好的结

日前,一项刊登在国际杂志New England Journal of Medicine的题为“Cord-Blood Transplantation in Patients with Minimal Residual Disease”的研究报告中,来自福瑞德哈金森肿瘤研究中心的研究人员通过研究表示,脐带血或许可以作为治疗成人和儿童白血病的优选方案,甚至在有些病例治疗过程中脐带血治疗还能够带来较好的结果。

为了比较不同方法治疗白血病的效果,研究者对582名白血病或骨髓增生异常综合征患者进行观察分析,如果来自无关供体相匹配的骨髓移植或干细胞移植不可用时,患者就会接受脐带血移植或来自无关供体的不相容骨髓移植或干细胞移植方法来治疗疾病。

研究者Filippo Milano说道,我们的研究表明,脐带血移植后患者的总体生存率和配对的无关移植的所观察到的结果往往是相当的,而且接受脐带血移植的患者似乎要比非配对骨髓移植或无关供体干细胞移植患者的寿命要长很多。脐带血移植的方法似乎对于微小残留白血病(minimal residual disease)患者尤其有益,而微小残留白血病是导致白血病复发,影响患者长期生存的重要因素

最后研究者说道,通常情况下,脐带血移植被认为仅仅是在没有供体情况下患者治疗的最后一把稻草,但实际上脐带血移植或许并不应当被认为是唯一的可替代的供体来源,在很多研究中心,其往往能够给患者带来较好的预后结果。


原始出处:
Filippo Milano, M.D., Ph.D., Ted Gooley, Ph.D., Brent Wood, M.D., Ann Woolfrey, M.D., Mary E. Flowers, M.D., et al.Cord-Blood Transplantation in Patients with Minimal Residual Disease.N Engl J Med 2016.

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    2016-10-11 童小孩

    脐带血治疗白血病

    0

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    2016-09-15 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

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    2016-09-15 Jackie Li

    收藏

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    2016-09-14 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

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