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Diabetes Care:动态血糖监测或可减少严重低血糖发生

2013-11-04 佚名 丁香园

为了评价动态血糖监测(CGM)对无意识性低血糖患者严重低血糖(SH)频率的影响。来自英国伦敦国王学院糖尿病和营养科学部的Choudhary等进行了一项研究,发现CGM能够减少SH发生频率,同时改善HbA1c水平。研究结果在线发表于2013年10月8日的美国《糖尿病治疗》(Diabetes Care)杂志上。【原文下载】 研究人员对35名1型糖尿病和可疑无意识性低血糖患


为了评价动态血糖监测(CGM)对无意识性低血糖患者严重低血糖(SH)频率的影响。来自英国伦敦国王学院糖尿病和营养科学部的Choudhary等进行了一项研究,发现CGM能够减少SH发生频率,同时改善HbA1c水平。研究结果在线发表于2013年10月8日的美国《糖尿病治疗》(Diabetes Care)杂志上。【原文下载】

研究人员对35名1型糖尿病和可疑无意识性低血糖患者进行回顾性检查。虽然这些患者接受了最佳的药物治疗(连续皮下注射胰岛素/一天多次胰岛素注射),但是已进行CGM>1年。

结果显示,1年随访期内,SH中位发生率从4.0次/人年(四分范围IQR 0.75-7.25)减少到0.0次/人年,平均发生率从8.1±13减少到0.6±1.2次/年。HbA1c水平从8.1 ± 1.2%降低到7.6 ± 1.0%.对19名患者测量的Gold评分没有改变,基线和1年后的平均Gold评分分别为:5.1 ± 1.5 和 5.2 ± 1.9.在专业经验丰富的胰岛素泵治疗中心,对经过仔细筛选的患者的研究表明,CGM能够减少SH发生频率,同时改善HbA1c水平,但是不能纠正低血糖所致意识障碍。

原文出处:

Choudhary P, Ramasamy S, Green L, Gallen G, Pender S, Brackenridge A, Amiel SA, Pickup JC.Real-Time Continuous Glucose Monitoring Significantly Reduces Severe Hypoglycemia in Hypoglycemia-Unaware Patients With Type 1 Diabetes.Diabetes Care. 2013 Oct 8.【原文下载】

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