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BMC Complement Altern Med:蜂毒针灸可能用于帕金森病的治疗

2014-07-21 MedSci MedSci原创

一项新的小型研究结果显示针灸和蜂毒针灸都可改善帕金森病患者的症状。这项研究发布于最近国际帕金森和运动障碍学会(MDS)第18届国际帕金森和运动障碍大会上。 该研究作者,韩国汉城Gangdong 的Kyung Hee 大学医院卒中和神经疾病中心的Seong-Uk Park博士在Medscape医学新闻中解释说,研究表明针灸或可通过增加多巴胺的外排和逆转化使帕金森病患者获益。研究也已显示它可提高L-多

一项新的小型研究结果显示针灸和蜂毒针灸都可改善帕金森病患者的症状。这项研究发布于最近国际帕金森和运动障碍学会(MDS)第18届国际帕金森和运动障碍大会上。

该研究作者,韩国汉城Gangdong 的Kyung Hee 大学医院卒中和神经疾病中心的Seong-Uk
Park博士在Medscape医学新闻中解释说,研究表明针灸或可通过增加多巴胺的外排和逆转化使帕金森病患者获益。研究也已显示它可提高L-多巴的效果及减轻副作用。[pdf free]

新加坡国家科学院的Louis Tan教授(他没有参与这项研究)评论研究结果说:“结果表明,针灸和蜂毒针灸均显著改善运动预后。这些结果很重要,因为已经发现,一些国家有高达70%的患者使用辅助疗法治疗帕金森病。”

稀释蜂毒

蜂毒针灸是指在一个穴位皮下注射稀释蜂毒,旨在增强和延长穴位的刺激作用。

Park博士说:“因此,蜂毒针灸的机制可能与针灸相似。或者可能蜂毒本身有另一种作用。”他补充说,蜂毒被认为有抗神经炎性作用,已被建议可能用于治疗神经退行性疾病。

研究中43例帕金森患者被随机分为3组:针灸,蜂毒针灸和对照组。针灸是将针刺入10个穴位,深度1.0至1.5厘米。针以2Hz旋转10秒,并在该位置保持20分钟。每周治疗2次,共8周。

试验期间14例患者退出,对剩余35例(针灸组13例,蜂毒针灸组13例,对照组9例)进行分析,各组的基线特征无明显差异。

蜂毒针灸组患者显示帕金森病统一评分量表(UPDRS)(总分,及第II和第III部分)、Berg平衡量表(BBS)和30米步行时间均明显改善。

在针灸组,UPDRS(第III部分和总分)及Beck抑郁调查(BDI)显著改善。对照组在8周后所有预后均无明显变化。

蜂毒针灸和针灸组都没有严重不良事件发生。蜂毒针灸组有一例患者报告有瘙痒。

Park博士承认,由于该研究中患者数量小而不能得出明确的结论,但他相信结果仍然是充满希望的。他补充说现在正在进行第二个试验,预计在今年晚些时候完成。

Tan博士说这项研究“延伸了领域,却是初步研究。”他在Medscape医学新闻中解释说,针灸研究一直被适当的控制问题所困扰。

Tan博士指出:“针灸常用于帕金森病,但其有效性缺乏确凿的证据。很难知道如何采用双盲方式控制针灸研究。你可以在非穴位部位刺入针,或者刺入皮肤但深度不足以产生针灸效果。这都是这一领域面临的挑战。”

他认为蜂毒的作用可能像肉毒杆菌一样,可导致肌肉短暂性麻痹。

原始出处:
Doo AR, Kim SN, Hahm DH, Yoo HH, Park JY, Lee H, Jeon S, Kim J, Park SU, Park HJ.Gastrodia elata Blume alleviates L-DOPA-induced dyskinesia by normalizing FosB and ERK activation in a 6-OHDA-lesioned Parkinson's disease mouse model.BMC Complement Altern Med. 2014 Mar 20;14:107[pdf free]


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    2015-02-06 shizhenshan
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    2015-01-09 w363522449
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    2015-02-27 xiaoai5777

    不错的文章,学习了

    0

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    2014-11-12 xuyong536
  5. [GetPortalCommentsPageByObjectIdResponse(id=1860969, encodeId=3dd818609694d, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Fri Feb 06 13:11:00 CST 2015, time=2015-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1779700, encodeId=09ee1e7970091, content=<a href='/topic/show?id=8a4123e754' target=_blank style='color:#2F92EE;'>#Altern#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2377, encryptionId=8a4123e754, topicName=Altern)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1c8c241, createdName=w363522449, createdTime=Fri Jan 09 13:11:00 CST 2015, time=2015-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=17096, encodeId=542d1e096de, content=不错的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=230, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36a81612921, createdName=xiaoai5777, createdTime=Fri Feb 27 15:33:00 CST 2015, time=2015-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773160, encodeId=a82d1e7316022, content=<a href='/topic/show?id=5298121e46e' target=_blank style='color:#2F92EE;'>#MPL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12174, encryptionId=5298121e46e, topicName=MPL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10e638510530, createdName=xuyong536, createdTime=Wed Nov 12 22:11:00 CST 2014, time=2014-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1783539, encodeId=1bd61e83539bc, content=<a href='/topic/show?id=f8db50319a' target=_blank style='color:#2F92EE;'>#Complement#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5031, encryptionId=f8db50319a, topicName=Complement)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Mon Feb 09 02:11:00 CST 2015, time=2015-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974575, encodeId=774619e45759d, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Sat Jul 04 09:11:00 CST 2015, time=2015-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1606243, encodeId=b78316062430a, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Wed Jul 23 14:11:00 CST 2014, time=2014-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=10564, encodeId=21261056477, content=国内很多年前就有人研究了,就是没发文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Mon Jul 21 23:36:00 CST 2014, time=2014-07-21, status=1, ipAttribution=)]
    2015-02-09 zsyan
  6. [GetPortalCommentsPageByObjectIdResponse(id=1860969, encodeId=3dd818609694d, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Fri Feb 06 13:11:00 CST 2015, time=2015-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1779700, encodeId=09ee1e7970091, content=<a href='/topic/show?id=8a4123e754' target=_blank style='color:#2F92EE;'>#Altern#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2377, encryptionId=8a4123e754, topicName=Altern)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1c8c241, createdName=w363522449, createdTime=Fri Jan 09 13:11:00 CST 2015, time=2015-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=17096, encodeId=542d1e096de, content=不错的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=230, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36a81612921, createdName=xiaoai5777, createdTime=Fri Feb 27 15:33:00 CST 2015, time=2015-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773160, encodeId=a82d1e7316022, content=<a href='/topic/show?id=5298121e46e' target=_blank style='color:#2F92EE;'>#MPL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12174, encryptionId=5298121e46e, topicName=MPL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10e638510530, createdName=xuyong536, createdTime=Wed Nov 12 22:11:00 CST 2014, time=2014-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1783539, encodeId=1bd61e83539bc, content=<a href='/topic/show?id=f8db50319a' target=_blank style='color:#2F92EE;'>#Complement#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5031, encryptionId=f8db50319a, topicName=Complement)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Mon Feb 09 02:11:00 CST 2015, time=2015-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974575, encodeId=774619e45759d, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Sat Jul 04 09:11:00 CST 2015, time=2015-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1606243, encodeId=b78316062430a, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Wed Jul 23 14:11:00 CST 2014, time=2014-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=10564, encodeId=21261056477, content=国内很多年前就有人研究了,就是没发文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Mon Jul 21 23:36:00 CST 2014, time=2014-07-21, status=1, ipAttribution=)]
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  8. [GetPortalCommentsPageByObjectIdResponse(id=1860969, encodeId=3dd818609694d, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Fri Feb 06 13:11:00 CST 2015, time=2015-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1779700, encodeId=09ee1e7970091, content=<a href='/topic/show?id=8a4123e754' target=_blank style='color:#2F92EE;'>#Altern#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2377, encryptionId=8a4123e754, topicName=Altern)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1c8c241, createdName=w363522449, createdTime=Fri Jan 09 13:11:00 CST 2015, time=2015-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=17096, encodeId=542d1e096de, content=不错的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=230, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36a81612921, createdName=xiaoai5777, createdTime=Fri Feb 27 15:33:00 CST 2015, time=2015-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773160, encodeId=a82d1e7316022, content=<a href='/topic/show?id=5298121e46e' target=_blank style='color:#2F92EE;'>#MPL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12174, encryptionId=5298121e46e, topicName=MPL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10e638510530, createdName=xuyong536, createdTime=Wed Nov 12 22:11:00 CST 2014, time=2014-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1783539, encodeId=1bd61e83539bc, content=<a href='/topic/show?id=f8db50319a' target=_blank style='color:#2F92EE;'>#Complement#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5031, encryptionId=f8db50319a, topicName=Complement)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Mon Feb 09 02:11:00 CST 2015, time=2015-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974575, encodeId=774619e45759d, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Sat Jul 04 09:11:00 CST 2015, time=2015-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1606243, encodeId=b78316062430a, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Wed Jul 23 14:11:00 CST 2014, time=2014-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=10564, encodeId=21261056477, content=国内很多年前就有人研究了,就是没发文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Mon Jul 21 23:36:00 CST 2014, time=2014-07-21, status=1, ipAttribution=)]
    2014-07-21 lovetcm

    国内很多年前就有人研究了,就是没发文章

    0

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