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JCEM:移民妊娠糖尿病风险

2020-01-18 xing.T MedSci原创

本研究表明,根据原住国,GDM的风险存在很大差异。风险关联仅受社会经济地位和BMI的轻微影响。

关于社会经济地位和体重指数(BMI)在种族、移民和妊娠糖尿病(GDM)联系中作用还有许多问题尚待明确。近日,内分泌和代谢性疾病领域权威杂志Journal of Clinical Endocrinology & Metabolism上发表了一篇研究文章,研究人员根据原住国以及社会经济地位和BMI对这种关联的作用,调查了GDM患病率的差异。最后,研究人员探究了居住时间与GDM之间的关系。

该基于登记的队列研究队列分析了2004-2015年期间丹麦出生的725482例孕妇。在这些受试者中,有14.4%是移民到丹麦的妇女。19386(2.7%)例孕妇诊断为GDM,其中4464例(23.0%)为移民妇女。与丹麦出生的妇女相比,根据母亲原住国划分的GDM的粗略风险范围,瑞典妇女OR为0.50 [95%CI为0.34-0.71],斯里兰卡妇女OR为5.11 [95%CI为4.28-6.11]。对社会经济地位的调整稍微减轻了风险。调整BMI后,尤其是亚洲国家/地区的女性的OR上升。迁徙和超重对GDM风险的单独和共同影响在原住国之间存在很大差异(相互作用p<0.0001)。与在丹麦居住时间短于五年的移民相比,居住时间≥10年的移民发生GDM的风险增加了56%(OR为1.56,95%CI为1.44-1.68)。当调整年龄和BMI时,这种风险有所降低。

本研究表明,根据原住国,GDM的风险存在很大差异。风险关联仅受社会经济地位和BMI的轻微影响。 

原始出处:

Karoline Kragelund Nielsen,et al.Gestational diabetes risk in migrants. A nation-wide register-based study of all births in Denmark 2004-2015.J Clin Endocrinol Metab.2020.https://doi.org/10.1210/clinem/dgaa024

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    2020-04-19 achengzhao
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    2020-09-02 smallant2015
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    2020-01-18 misszhang

    谢谢MedSci提供最新的资讯

    0

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    2020-01-18 陈致远

    学习了,很好的资料

    0

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