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Clinica Chimica Acta:钙卫蛋白和乳铁蛋白是否等同于炎症性肠病的筛查试验?

2020-08-09 MedSci原创 MedSci原创

乳铁蛋白和钙卫蛋白经常被要求进行粪便测试,用于筛查炎症性肠病和功能性肠病。目前的指南建议使用其中一种来筛查消化道炎症;然而,关于这两种测定方法的比较及其在不同临床专科中的应用的信息很少。

乳铁蛋白和钙卫蛋白经常被要求进行粪便测试,用于筛查炎症性肠病和功能性肠病。目前的指南建议使用其中一种来筛查消化道炎症;然而,关于这两种测定方法的比较及其在不同临床专科中的应用的信息很少。

研究人员利用大型参考实验室10年(2009-2019年)的数据,比较了乳铁蛋白和钙卫蛋白的顺序模式。还研究了乳铁蛋白和钙卫蛋白在两种检测同时进行的情况下的一致性。最后,回顾了一所大学医院的记录,以确定哪些临床医生下达了每项检查的命令以及与命令相关的适应症。

钙卫蛋白的订单相对于乳铁蛋白正在增加。 在过去十年中,钙卫蛋白订单的相对比例已从60%增加到近90%。 乳铁蛋白和钙卫蛋白的结果一致(90%)。 钙卫蛋白和乳铁蛋白由不同的临床专业根据不同的适应症进行订购。 肠胃病学家最常在腹痛的情况下订购钙卫蛋白。 在急性腹泻的情况下,乳铁蛋白通常是由初级保健提供者订购的。

根据目前已经有的研究结果,研究认为临床医生并未将乳铁蛋白和钙卫蛋白作为等效试验处理。

原始出处:

Lisa M.Johnson,Sandra K.White,Are calprotectin and lactoferrin equivalent screening tests for inflammatory bowel disease?

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    2021-01-04 windight
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    2020-09-16 lovetcm

    #钙卫蛋白#近年来比较火

    0

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