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Hypertension：什么！左心室质量与认知有关！

2017-09-15 MedSci MedSci原创

左心室质量认知
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已有研究显示，左心室质量（LVM）可以作为长期接触一些危险因素所致靶器官损伤的检测方法。但是，目前关于中年时期LVM与以后认知表现相关的研究数据很少。近期，一项发表在杂志Hypertension上的研究评估了入组强心脏研究（SHS，1993-1995）和辅助CDCAI（脑血管病及其后裔美国印第安人）研究（2010-2013）中的721名成人（基线时平均年龄56岁）的情况。基线的LVM在1993年至

已有研究显示，左心室质量（LVM）可以作为长期接触一些危险因素所致靶器官损伤的检测方法。但是，目前关于中年时期LVM与以后认知表现相关的研究数据很少。


近期，一项发表在杂志Hypertension上的研究评估了入组强心脏研究（SHS，1993-1995）和辅助CDCAI（脑血管病及其后裔美国印第安人）研究（2010-2013）中的721名成人（基线时平均年龄56岁）的情况。

基线的LVM在1993年至1995年通过经胸超声心动图进行评估。颅脑磁共振成像和认知测试在2010年至2013年间进行。使用广义估计方程建立LVM与后期成像和认知结果之间的关联。平均随访期为17年。

最终，研究结果显示：较高LVM的差异为25g，其与海马体积小幅度下降（0.01％; 95％置信区间，0.02-0.00; P = 0.001）和较高的白质等级（0.10; 95％置信区间，0.02-0.18; P = 0.014）相关。在功能上，具有较高LVM的受试者在修改的迷你精神状态检查量表中的得分略低（0.58; 95％置信区间，1.08-0.08; P = 0.024）。调整血压水平或血管疾病后，上诉主要结果仍然存在。

此项研究结果表明了心血管健康在中年人群中的意义，其可以作为预防以后生活中认知功能下降的靶点。

原始出处：
Haring B, Omidpanah A, et al. Left Ventricular Mass, Brain Magnetic Resonance Imaging, and Cognitive Performance: Results From the Strong Heart Study. Hypertension. 2017 Sep 11. pii: HYPERTENSIONAHA.117.09807. doi: 10.1161/HYPERTENSIONAHA.117.09807. 

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    2018-06-03 feather89

    #PE#

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    2018-07-07 12498ebem19暂无昵称

    #TENS#

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    2017-11-04 wangtianj2015@

    #左心室质量#

    0

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    2017-09-17 wushaoling

    #左心室#

    0

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    2017-09-17 jambiya

    #Hypertension#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1726726, encodeId=c6f31e26726a7, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sun Jun 03 08:24:00 CST 2018, time=2018-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2038751, encodeId=201b2038e51a5, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Sat Jul 07 00:24:00 CST 2018, time=2018-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1650966, encodeId=e3481650966d6, content=<a href='/topic/show?id=a9c84806017' target=_blank style='color:#2F92EE;'>#左心室质量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48060, encryptionId=a9c84806017, topicName=左心室质量)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057924108593, createdName=wangtianj2015@, createdTime=Sat Nov 04 22:24:00 CST 2017, time=2017-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1413204, encodeId=bb9d1413204b4, content=<a href='/topic/show?id=1d7e48033f5' target=_blank style='color:#2F92EE;'>#左心室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48033, encryptionId=1d7e48033f5, topicName=左心室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=15012955474, createdName=wushaoling, createdTime=Sun Sep 17 01:24:00 CST 2017, time=2017-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501203, encodeId=00df15012038e, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Sun Sep 17 01:24:00 CST 2017, time=2017-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244345, encodeId=c3b124434532, content=谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f622099626, createdName=1331f63a52m, createdTime=Fri Sep 15 17:03:16 CST 2017, time=2017-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244321, encodeId=a9ef24432165, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Fri Sep 15 13:41:45 CST 2017, time=2017-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244296, encodeId=4e8324429655, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Fri Sep 15 12:18:12 CST 2017, time=2017-09-15, status=1, ipAttribution=)]
    2017-09-15 1331f63a52m

    谢谢分享.

    0

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    2017-09-15 清风拂面

    谢谢分享.学习了

    0

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    2017-09-15 惠映实验室

    学习了.谢谢.

    0

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