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Prostate Cancer P D:前列腺癌中质子放射治疗与光子放射治疗比较

2019-04-23 AlexYang MedSci原创

放射技术的进展改变了局部前列腺癌患者的治疗选择。三维适形放射治疗和可调节强度放射治疗(IMRT)使得医生可以避免邻近正常组织受放射影响,从而减少副作用事件。质子束技术的引入及其在病理组织中能量具有最大范围的物理优势,有可能为前列腺癌患者避免膀胱和直肠等关键器官遭受影响。目前的数据局限于大的和观察性的研究,并且并没有阐释清楚质子治疗比IMRT传统治疗方法的优势。另外,质子束放射治疗的花费也增加了该治

放射技术的进展改变了局部前列腺癌患者的治疗选择。三维适形放射治疗和可调节强度放射治疗(IMRT)使得医生可以避免邻近正常组织受放射影响,从而减少副作用事件。质子束技术的引入及其在病理组织中能量具有最大范围的物理优势,有可能为前列腺癌患者避免膀胱和直肠等关键器官遭受影响。目前的数据局限于大的和观察性的研究,并且并没有阐释清楚质子治疗比IMRT传统治疗方法的优势。另外,质子束放射治疗的花费也增加了该治疗方法的争议。

最近,有研究人员进行了对所有的与前列腺癌相关的质子治疗进行了大量的文献调查。研究人员讨论了质子束技术的历史,以及在前列腺癌治疗中的角色,相关的矛盾,新技术驱使以及花费的讨论,以及现代大规模前瞻性研究总述。研究发现,与前列腺癌的标准治疗选择相比,质子束放射治疗是安全的和有效的。虽然剂量测定研究表明了质子治疗比光子治疗具有更低的全身辐射剂量以及理论上相对更高的生物学效应,还没有研究详细的阐释质子治疗的益处。

最后,研究人员指出,质子治疗的传输以及质子中心商务模式的发展趋势有助于减少花费。现存技术引入质子传输可以实现对器官运动进一步的控制并处理患病器官。另外,比较光子和质子治疗的研究并且包括患者报道的生活质量结果将会帮助人们理解质子和光子治疗在前列腺癌中的差异。

原始出处:


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  2. [GetPortalCommentsPageByObjectIdResponse(id=1791574, encodeId=48b61e915742b, content=<a href='/topic/show?id=b77f14e4541' target=_blank style='color:#2F92EE;'>#Prostate Ca#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14745, encryptionId=b77f14e4541, topicName=Prostate Ca)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a691420, createdName=30397604, createdTime=Mon Jul 15 19:52:00 CST 2019, time=2019-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364478, encodeId=884013644e824, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Thu Apr 25 04:52:00 CST 2019, time=2019-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1602149, encodeId=742b160214944, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Thu Apr 25 04:52:00 CST 2019, time=2019-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1630252, encodeId=4b5f163025218, content=<a href='/topic/show?id=7d2764661f6' target=_blank style='color:#2F92EE;'>#治疗比较#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64661, encryptionId=7d2764661f6, topicName=治疗比较)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cbf021471003, createdName=zhangyxzsh, createdTime=Thu Apr 25 04:52:00 CST 2019, time=2019-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1040440, encodeId=6b01104044016, content=前列腺癌相关研究,学习了,谢谢梅斯, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Tue Apr 23 16:52:00 CST 2019, time=2019-04-23, status=1, ipAttribution=)]
    2019-04-25 lsndxfj
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    2019-04-25 sunylz
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    2019-04-23 misszhang

    前列腺癌相关研究,学习了,谢谢梅斯

    0

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世界范围内,前列腺癌是仅次于肺癌的男性诊断疾病。甚至是最好的诊断标准仍旧缺乏精度,导致组织检测的假阳性从而导致患者接受不必要的外科手术干预。明确的早期诊断工具的缺乏是一个很明显的问题。最近,有研究人员呈现了微流体平台,时间分辨流体力学拉伸器(TR-HS),该设备可以允许每秒内对上千个细胞的非破坏性应力进行动态的力学响应调查。TR-HS整合了高速成像和计算机视觉,从而实现悬浮于液体中单个细胞的自动化

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