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Int J Oral Surg:黏膜下注射地塞米松和甲基强的松龙抑制第三磨牙术后并发症

2018-01-09 MedSci MedSci原创

疼痛,肿胀和张口受限是常见的第三磨牙术后并发症,可以显着影响个人的生活质量(QOL)。这些症状应该最小化以提高生活质量。

疼痛,肿胀和张口受限是常见的第三磨牙术后并发症,可以显着影响个人的生活质量(QOL)。这些症状应该最小化以提高生活质量。

本研究的目的是比较术前黏膜下给予等剂量两种常用类固醇对这些术后并发症的影响。一项随机对照临床试验纳入60名需要拔除下颌第三磨牙受试者,病例均具有类似难度指数。参与者被随机分配到三组:安慰剂组接受生理盐水注射(对照),而实验组包括8mg地塞米松组和40mg甲基强的松龙组。每位参与者通过结构化问卷调查评估术后疼痛,肿胀和张口状况,以及生活质量的主观评估。与对照组相比,接受地塞米松治疗的患者疼痛和关节强度明显减少(P <0.05)。粘膜下注射地塞米松仅在肿胀减少方面优于甲泼尼龙。与甲基泼尼松龙和对照受试者相比,地塞米松组患者的生活质量受到的影响最小。术前粘膜下使用类固醇可以被认为是一种有效的,安全的,简单的治疗方式,可以用于减少下颌第三磨牙拔除后的肿胀,疼痛和张口受限。

原始出处:

A. Chugh, et al. Submucosal injection of dexamethasone and methylprednisolone for the control of postoperative sequelae after third molar surgery: randomized controlled trial. International Journal of Oral and Maxillofacial Surgery. 2018 February. doi:http://dx.doi.org/10.1016/j.ijom.2017.07.022

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    2018-10-07 小几洁
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  3. 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time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576154, encodeId=879f15e615403, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=570716304996, createdName=12498474m35暂无昵称, createdTime=Wed Jan 10 15:03:00 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=277087, encodeId=c4ce2e708717, content=术前粘膜下使用类固醇可以被认为是一种有效的.安全的.简单的治疗方式.可以用于减少下颌第三磨牙拔除后的肿胀.疼痛和张口受限., beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Wed Jan 10 07:19:29 CST 2018, time=2018-01-10, status=1, ipAttribution=)]
    2018-11-11 丁鹏鹏
  4. 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  5. 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href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Wed Jan 10 15:03:00 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556996, encodeId=ca1e155699647, content=<a href='/topic/show?id=394969e8925' target=_blank style='color:#2F92EE;'>#甲基强的松龙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69789, encryptionId=394969e8925, topicName=甲基强的松龙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a9714846461, createdName=wjywjy, createdTime=Wed Jan 10 15:03:00 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576154, encodeId=879f15e615403, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=570716304996, createdName=12498474m35暂无昵称, createdTime=Wed Jan 10 15:03:00 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=277087, encodeId=c4ce2e708717, content=术前粘膜下使用类固醇可以被认为是一种有效的.安全的.简单的治疗方式.可以用于减少下颌第三磨牙拔除后的肿胀.疼痛和张口受限., beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Wed Jan 10 07:19:29 CST 2018, time=2018-01-10, status=1, ipAttribution=)]
    2018-01-11 jyzxjiangqin

    磨牙术后并发症.

    0

  6. 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href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Wed Jan 10 15:03:00 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556996, encodeId=ca1e155699647, content=<a href='/topic/show?id=394969e8925' target=_blank style='color:#2F92EE;'>#甲基强的松龙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69789, encryptionId=394969e8925, topicName=甲基强的松龙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a9714846461, createdName=wjywjy, createdTime=Wed Jan 10 15:03:00 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576154, encodeId=879f15e615403, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=570716304996, createdName=12498474m35暂无昵称, createdTime=Wed Jan 10 15:03:00 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=277087, encodeId=c4ce2e708717, content=术前粘膜下使用类固醇可以被认为是一种有效的.安全的.简单的治疗方式.可以用于减少下颌第三磨牙拔除后的肿胀.疼痛和张口受限., beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Wed Jan 10 07:19:29 CST 2018, time=2018-01-10, status=1, ipAttribution=)]
    2018-01-10 snowpeakxu
  7. 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  8. [GetPortalCommentsPageByObjectIdResponse(id=2020346, encodeId=625d20203464f, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Sun Oct 07 06:03:00 CST 2018, time=2018-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1756790, encodeId=99a71e5679039, content=<a href='/topic/show?id=84065018044' target=_blank style='color:#2F92EE;'>#强的松#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50180, encryptionId=84065018044, topicName=强的松)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee9d37231037, createdName=ms6829001416292975, createdTime=Mon Dec 10 02:03:00 CST 2018, time=2018-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1757923, encodeId=675d1e57923e8, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a27e37327108, createdName=丁鹏鹏, createdTime=Sun Nov 11 19:03:00 CST 2018, time=2018-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1651372, encodeId=378616513e2fe, content=<a href='/topic/show?id=0e39e5792aa' target=_blank style='color:#2F92EE;'>#第三磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75792, encryptionId=0e39e5792aa, topicName=第三磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c6124182829, createdName=zexyw09, createdTime=Sat Feb 17 11:03:00 CST 2018, time=2018-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=277425, encodeId=e0612e742501, content=磨牙术后并发症., beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Thu Jan 11 07:13:38 CST 2018, time=2018-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519989, encodeId=062f1519989e4, content=<a href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Wed Jan 10 15:03:00 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556996, encodeId=ca1e155699647, content=<a href='/topic/show?id=394969e8925' target=_blank style='color:#2F92EE;'>#甲基强的松龙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69789, encryptionId=394969e8925, topicName=甲基强的松龙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a9714846461, createdName=wjywjy, createdTime=Wed Jan 10 15:03:00 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576154, encodeId=879f15e615403, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=570716304996, createdName=12498474m35暂无昵称, createdTime=Wed Jan 10 15:03:00 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=277087, encodeId=c4ce2e708717, content=术前粘膜下使用类固醇可以被认为是一种有效的.安全的.简单的治疗方式.可以用于减少下颌第三磨牙拔除后的肿胀.疼痛和张口受限., beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Wed Jan 10 07:19:29 CST 2018, time=2018-01-10, status=1, ipAttribution=)]
  9. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75792, encryptionId=0e39e5792aa, topicName=第三磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c6124182829, createdName=zexyw09, createdTime=Sat Feb 17 11:03:00 CST 2018, time=2018-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=277425, encodeId=e0612e742501, content=磨牙术后并发症., beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Thu Jan 11 07:13:38 CST 2018, time=2018-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519989, encodeId=062f1519989e4, content=<a href='/topic/show?id=6ab11032506f' target=_blank style='color:#2F92EE;'>#黏膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103250, encryptionId=6ab11032506f, topicName=黏膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=057f11309297, createdName=snowpeakxu, createdTime=Wed Jan 10 15:03:00 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556996, encodeId=ca1e155699647, content=<a href='/topic/show?id=394969e8925' target=_blank style='color:#2F92EE;'>#甲基强的松龙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69789, encryptionId=394969e8925, topicName=甲基强的松龙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a9714846461, createdName=wjywjy, createdTime=Wed Jan 10 15:03:00 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576154, encodeId=879f15e615403, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=570716304996, createdName=12498474m35暂无昵称, createdTime=Wed Jan 10 15:03:00 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=277087, encodeId=c4ce2e708717, content=术前粘膜下使用类固醇可以被认为是一种有效的.安全的.简单的治疗方式.可以用于减少下颌第三磨牙拔除后的肿胀.疼痛和张口受限., beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Wed Jan 10 07:19:29 CST 2018, time=2018-01-10, status=1, ipAttribution=)]
    2018-01-10 往日如昨

    术前粘膜下使用类固醇可以被认为是一种有效的.安全的.简单的治疗方式.可以用于减少下颌第三磨牙拔除后的肿胀.疼痛和张口受限.

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