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Clin Otolaryngol:过敏性鼻炎,而不是哮喘是龋齿的一个风险因子

2017-06-17 AlexYang MedSci原创

哮喘(AS)与龋齿的相互关系是具有争议的,然而过敏性鼻炎(AR)与龋齿的关系仍旧还未建立。最近,有研究人员证实了AR、AS和龋齿之间的关系。该研究是一个回顾性的群体研究。数据是来自于台湾地区医疗保险数据库。参与者包括9380名出生在2004年的儿童,并对他们的从出生到9岁的数据进行了评估。研究人员对最初牙齿阶段(1-5岁)的龋齿临床访问频率和替牙阶段(6-9岁)的临床访问频率进行了计算。并对龋齿临

哮喘(AS)与龋齿的相互关系是具有争议的,然而过敏性鼻炎(AR)与龋齿的关系仍旧还未建立。最近,有研究人员证实了AR、AS和龋齿之间的关系。该研究是一个回顾性的群体研究。数据是来自于台湾地区医疗保险数据库。参与者包括9380名出生在2004年的儿童,并对他们的从出生到9岁的数据进行了评估。

研究人员对最初牙齿阶段(1-5岁)的龋齿临床访问频率和替牙阶段(6-9岁)的临床访问频率进行了计算。并对龋齿临床访问频率在AR、non-AR和AS、non-AS儿童之间的差异进行了比较。研究了AR、AS和龋齿频率的联系,以及对AR药物对龋齿发展的影响进行了评估。

研究发现,在调整了混杂因素和AS案例后,龋齿的临床访问频率在AR中更高(约增加了13-25%且在不同的年龄阶段p<0.001)。在AR儿童中,AR的频率显著的与龋齿频率相关。另外,不同的AR药物同样与龋齿形成相关。在调整了混杂因素和AR案例后,在儿童中,AS和龋齿并没有关系。最后,研究人员指出,哮喘与龋齿没有相关关系,而过敏性鼻炎可以增加龋齿的临床访问频率。AR的药物治疗同样在龋齿的形成中起着重要作用。因此,AR也许可以作为儿童龋齿的一个风险因子。

原始出处:

Chuang CY, Sun H, Ku MS et al. Allergic rhinitis, rather than asthma, is a risk factor for dental caries. Clin Otolaryngol. 6 June 2017.

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    2017-06-18 lovetcm

    总感觉很多研究因果对立了

    0

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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sun Jun 18 00:30:49 CST 2017, time=2017-06-18, status=1, ipAttribution=)]
    2017-06-18 虈亣靌

    非常好的内容,学习了,很受益。

    0

  5. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sun Jun 18 00:30:49 CST 2017, time=2017-06-18, status=1, ipAttribution=)]
    2017-06-18 明月清辉

    谢谢分享,学习了

    0

  6. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sun Jun 18 00:30:49 CST 2017, time=2017-06-18, status=1, ipAttribution=)]
    2017-06-18 1dd7a091m35(暂无匿称)

    学习了。。。。。。

    0

  7. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sun Jun 18 00:30:49 CST 2017, time=2017-06-18, status=1, ipAttribution=)]
    2017-06-18 thlabcde

    好东西学习了!

    0

  8. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sun Jun 18 00:30:49 CST 2017, time=2017-06-18, status=1, ipAttribution=)]
    2017-06-18 Y—xianghai

    学习了新知识

    0

  9. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sun Jun 18 00:30:49 CST 2017, time=2017-06-18, status=1, ipAttribution=)]
    2017-06-18 Julie W

    AR也许可以作为儿童龋齿的一个风险因子。

    0

  10. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sun Jun 18 00:30:49 CST 2017, time=2017-06-18, status=1, ipAttribution=)]
    2017-06-18 飛歌

    学习了,这个还真有用

    0

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Th2细胞激素就像白介素-4、-5和-13,被认为是过敏性鼻炎(AR)和哮喘的免疫病理学的重要驱使因子。最近,有研究人员探索了一种半合成的类肝素大分子碳水化合物-木聚硫钠(PPS)体内结合Th2细胞激素和发挥生物学中和作用以及抗炎症作用的能力。研究人员利用表面等离子共振(SPR)来检测PPS结合重组的Th2的能力,并利用Th2依赖的细胞增殖分析实验评估了生物学Th2中和作用。另外,利用鉴定过的AR

Sleep Breath:CPAP在阻塞性呼吸暂停病人中的影响:过敏性鼻炎与之相关么?

最近,有研究人员比较了睡眠窒息症病人中,持续气道正压通气(CPAP)对患有或者不患有过敏性鼻炎(AR/non AR)病人的影响。研究人员设计了一个预期的和纵向的研究。研究包括了34名持续性CPAB治疗的OSA病人,并且他们中17名有过敏性鼻炎,17名不患有过敏性鼻炎。在治疗前和治疗后2个月,研究人员评估了他们的临床参数(耳鼻喉症状、日间嗜睡度、总的鼻炎相关生活品质)、解剖学参数(耳鼻喉检查)、功能

Sci Rep:舌下腺尘螨免疫疗法在过敏性鼻炎的气道过敏原挑战中对循环红细胞的减少并没有影响

屋尘螨(HDM)过敏在欧洲是一种四季过敏性鼻炎(AR)的主要起因。之前,有研究人员报道了在一个哮喘小鼠模型中和草花粉敏感的AR病人中,循环红细胞数目的减少。最近,研究人员评估了在HDM敏感AR病人中的这些发现,并且评估了先前过敏免疫疗法的影响。先前在维也纳挑战室(VCC)的一个随机的、单中心的舌下免疫疗法(SLIT)试验中征集的77名HDM过敏性鼻炎病人(年龄在26.8±7.3岁;54.5%为女性

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最近,有研究人员调查了槲皮素在实验过敏性鼻炎小鼠模型中是否具有治疗作用进行了研究。该研究包括了35只小鼠,并且被随机分成了四组:组1(n=5),假手术组;组2(n=10),槲皮素组,并接受80mg/kg每天的槲皮素量;组3(类固醇组,n=10),接受类固醇(糠酸莫米松);组4为对照组(n=10),只接受卵清蛋白。研究人员通过每天交替的腹腔注射的方法将小鼠利用卵清蛋白敏感化。在第15天,除了腹腔注射

Allergol Int: 日本青少年中,HLA-DPB1与日本柳杉花粉病和致敏作用的关系

过敏性鼻炎(AR)是一种多样化的障碍疾病并且能够显著的影响日常活动、工作效率、睡眠、学习以及生活质量。日本柳杉(JC)花粉是日本最普遍的AR的过敏原。由JC花粉引起的AR被认为是一种多因子的遗传性疾病,且有环境和遗传因素共同导致的。最近,有研究人员就人类白细胞抗原-PDB1(HLA-DPB1)与JC花粉病和致敏性的关系进行了研究。研究包含了2013年到2015年的544名来自日本筑波大学的学生,并

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