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2021 ACR:膝关节骨关节炎的超声评估及其与X射线的一致性

2021-11-27 MedSci原创 MedSci原创

本研究旨在1) 表征膝关节OA的超声特征及其与疼痛和功能水平的关系,以及2)确定超声与常规X射线在膝关节OA评估中的相关性和一致性。

超声检查(US)已越来越多地用于评估各种肌肉骨骼状况。然而,US在临床实践中诊断骨关节炎(OA)的价值仍不清楚。本研究旨在1) 表征膝关节OA的超声特征及其与疼痛和功能水平的关系,以及2)确定超声与常规X射线在膝关节OA评估中的相关性和一致性。

     方法20188月至20198月期间,在Cho Ray医院风湿科门诊对14540岁及以上(83.4%女性)、平均年龄为61.7岁、临床诊断为原发性膝关节OA的患者进行横断面研究。排除伴有炎症性关节病的患者。使用视觉模拟量表(VAS) 进行临床疼痛评估,使用西安大略和麦克马斯特大学关节炎指数 (WOMAC)对所有受试者的功能状态进行评估,接受膝关节X光和US检查。研究了超声检查结果与临床和放射学特征之间的相关性。

共评估了290个膝关节。US最常见的特征是软骨厚度降低(74.5%)、骨赘 (66.9%)、积液(55.9%)、内侧半月板挤压(78.6%)、外侧半月板挤压(39.3%)、滑膜增厚 (17.2%) )和贝克囊肿(15.2%)VASWOMAC疼痛评分与US测量的积液水平和骨赘大小呈正相关,与股骨内侧软骨厚度呈负相关。超声内侧软骨厚度与X线内侧关节间隙宽度(rs = 0.3p < 0.01)以及超声和X线骨赘分级之间呈正相关(内侧和外侧关节间隙分别为rs = 0.69p < 0.01rs = 0.47p < 0.01)。129 (44.5%)膝盖在超声和X光片上均发现骨赘,44(34.1%)膝盖只在US检查中发现骨赘,17(13.2%) 膝仅在X光检查中发现骨赘 (Kappa = 0.58p < 0.01)

这些结果支持超声检查与传统X线相比在评估膝关节OA病变方面的有效性。此外,在检测膝关节OA的早期变化(如软骨损伤和轻度骨赘)方面,超声似乎比X射线更敏感。

原始出处:

Nguyen K, Tran D. Ultrasonographic Assessment of Knee Osteoarthritis and Its Agreement with Radiography [abstract]. Arthritis Rheumatol. 2021; 73 (suppl 10).

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    2021-12-26 lisa438
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    2022-11-05 zhanfl
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    2021-12-29 medsci256
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    2022-01-14 胡国宏
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    2021-11-28 lmm397
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