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剧烈干咳,一针生理盐水就搞定?

2017-06-14 陈培填 医学界儿科频道

心因性咳嗽?什么鬼?

最近有这么一个病例,持续、剧烈干咳,2-3声/阵,每阵间歇数秒,偶可自行抑制咳嗽,最多可持续2-3分,无昼夜差异,清醒时出现,睡眠时消失,经诊疗后,予一针生理盐水肌注后,第二天患儿咳嗽明显减轻,第三天出院,这到底是什么病呢?生理盐水是特效药?

首先,我们来看看这个病例

患儿女,11岁,因"咳嗽2周"来诊,入院2周前无明显诱因开始出现持续性干咳,伴咽喉部异物感,无伴痰声,无流涕,无鼻塞,无喘息,无反酸,无心悸,无胸闷,清醒时出现,睡眠时无咳嗽,无夜间咳醒,无明显昼夜差别,与进食、体位无关,无明显诱发因素,病初伴发热1次,曾就诊,查胸片未见异常,服用退烧药后无再发热,咳嗽无好转,再次就诊予氧驱雾化、静脉输液(具体不详)治疗4天,效果不佳,来诊,拟"心因性咳嗽?"收住。患儿既往身体健康,一般体育活动后无胸闷、气促,无呼吸困难。3年前开始偶有不自主清咽动作。否认喘息、先心病、肺结核、异物吸入史。出生史无特殊,现读小学五年级,学习成绩优秀。

查体:T 36.5°C,R 26次/分,P 109次/分,BP 101/66mmHg,SPO2 98%(空气下),Wt 45kg(P75),身高155cm(P75)。神志清,精神可,发育正常,营养中等,全身皮肤粘膜无皮疹及皮下出血点。浅表淋巴结未扪及肿大。外耳道无异常分泌物。副鼻窦区无压痛。咽无充血,双侧扁桃体无肿大。呼吸平顺,双肺呼吸音粗,左右对称,未闻及干湿性啰音。心、腹部查体(-)。

辅助检查:白细胞稍高,13.5×109?/L(NEUT% 53.5%;LY% 38.4%),心肝肾功能、CRP、PCT、ESR、丙型肝炎抗体、Anti-HIV、乙肝二对半、梅毒未见异常。肺炎支原体抗体(+/-)。胸片:两下肺纹理增粗、紊乱、模糊;两肺门略增浓,考虑支气管炎改变。纤维支气管镜检查、肺功能未见异常。

诊疗过程:入院后予布地奈德氧驱雾化、孟鲁斯特+氮卓斯汀减轻气道高反应、补液及其他对症支持治疗。经治疗后,患儿清醒状态下仍剧烈咳嗽,较前无明显减轻。予完善胸片、纤维支气管镜检查、肺功能等检查,排除了支气管肺炎、异物吸入、咳嗽变异性哮喘可能,而慢性咳嗽较常见的上气道咳嗽综合症,无病史支持,且该患儿剧烈干咳与该病表现不符合,亦不考虑(患儿咳嗽已3周,暂不属于慢性咳嗽范围)。予追问病史,发现患儿家长家庭富裕,但平时工作繁忙,有4个孩子,患儿为老大,有2个弟弟和1个妹妹,妹妹(9岁)平时在住宿学习,近期在家中,该患儿成绩虽优秀,但家长不甚满意,要求较为严厉,近期曾因在课堂上不自主清咽动作被老师谈话,同座因家庭原因转学。

结合患儿病史、查体及辅助检查结果,考虑患儿咳嗽为心理疾病所致可能大,心因性咳嗽可能,与家属独谈后,再与患儿沟通,并暗示将予一针特效止咳针肌注,予告知肌注后咳嗽症状将消失,肌注后第二天患儿咳嗽明显减轻,肌注后第三天患儿偶有咳嗽,无发热,出院。

目前对心因性咳嗽的报道甚少,该病特点为:年长儿为多见(常见于学龄期和青春期患儿),常有焦虑症状,可有咽喉部发痒表现,但无器质性病变,属排他性诊断,可由上呼吸道感染诱发,咳嗽表现为干咳,呈犬吠声或雁鸣样咳嗽,咳嗽无昼夜差异,前往就诊时明显,夜间睡眠后消失,或患儿专注于某件事情时咳嗽消失或减轻,辅助检查多无明显异常,与剧烈咳嗽不相符,经抗感染、止咳及雾化等治疗效果差。目前对该病的诊断尚无定论,在排除其他病变可能后,进行心理干预治疗(包括暗示疗法、自我催眠及生物反馈等),患儿咳嗽能得到改善,方能诊断心因性咳嗽。

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    2017-11-05 bioon15
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beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2JlGvwpAibiaovVhfA9DbO7X7JLGGjM4Cic6oMgxLdnuS9piaP9cnG2OwIbkzHvX0qzS1boibyYNqR5vHZu7HQs5EIB/0, createdBy=298d1398341, createdName=lou.minghong, createdTime=Thu Jun 15 08:00:46 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=210971, encodeId=aae42109e1a9, content=非常好的文章,学习了,很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Thu Jun 15 07:30:07 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=210955, encodeId=d485210955fa, content=特殊病例讨论,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Jun 15 07:07:52 CST 2017, time=2017-06-15, status=1, ipAttribution=)]
    2017-06-27 vcochan

    心因性的确应该在日后重视起来

    0

  4. 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    2017-06-18 139****5926

    好文章学习了

    0

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    2017-06-15 139****5926

    好文章学习了

    0

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beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2JlGvwpAibiaovVhfA9DbO7X7JLGGjM4Cic6oMgxLdnuS9piaP9cnG2OwIbkzHvX0qzS1boibyYNqR5vHZu7HQs5EIB/0, createdBy=298d1398341, createdName=lou.minghong, createdTime=Thu Jun 15 08:00:46 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=210971, encodeId=aae42109e1a9, content=非常好的文章,学习了,很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Thu Jun 15 07:30:07 CST 2017, time=2017-06-15, status=1, ipAttribution=), 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    2017-06-15 戒馋,懒,贪

    有意思,安慰剂

    0

  7. 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    2017-06-15 我是谁??

    学习了。。。。。。

    0

  8. 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    2017-06-15 lou.minghong

    安慰剂效应

    0

  9. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2JlGvwpAibiaovVhfA9DbO7X7JLGGjM4Cic6oMgxLdnuS9piaP9cnG2OwIbkzHvX0qzS1boibyYNqR5vHZu7HQs5EIB/0, createdBy=298d1398341, createdName=lou.minghong, createdTime=Thu Jun 15 08:00:46 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=210971, encodeId=aae42109e1a9, content=非常好的文章,学习了,很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Thu Jun 15 07:30:07 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=210955, encodeId=d485210955fa, content=特殊病例讨论,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Jun 15 07:07:52 CST 2017, time=2017-06-15, status=1, ipAttribution=)]
    2017-06-15 天涯183

    非常好的文章,学习了,很受益

    0

  10. 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createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Sun Jun 18 21:30:15 CST 2017, time=2017-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=211081, encodeId=30ea2110819c, content=好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Thu Jun 15 11:10:58 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=211076, encodeId=2a022110e6cd, content=有意思,安慰剂, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Thu Jun 15 10:35:18 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=211028, encodeId=c963211028b5, content=学习了。。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo51eheDrP8dFkRicVB5LyaVk2Nc1S87J8nCBgASWQ4rrorsyzzr0UzN8N5bibeqGofE7ZtdT6YNZHEQ/0, createdBy=28d72072417, createdName=我是谁??, createdTime=Thu Jun 15 08:16:01 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=210996, encodeId=1a9d2109965b, content=安慰剂效应, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2JlGvwpAibiaovVhfA9DbO7X7JLGGjM4Cic6oMgxLdnuS9piaP9cnG2OwIbkzHvX0qzS1boibyYNqR5vHZu7HQs5EIB/0, createdBy=298d1398341, createdName=lou.minghong, createdTime=Thu Jun 15 08:00:46 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=210971, encodeId=aae42109e1a9, content=非常好的文章,学习了,很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Thu Jun 15 07:30:07 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=210955, encodeId=d485210955fa, content=特殊病例讨论,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu Jun 15 07:07:52 CST 2017, time=2017-06-15, status=1, ipAttribution=)]
    2017-06-15 惠映实验室

    特殊病例讨论,学习了

    0

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