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Ann Rheum Dis:新发中轴型脊柱关节炎的骶髂关节影像学进展

2017-07-07 xiangting MedSci原创

新发病的axSpA患者X-SIJ损伤的五年进展是有限的,但在测量误差外是真实存在的。

这项研究旨在评估中轴型脊柱关节炎(axSpA)患者骶髂关节影像学(X-SIJ)进展,并评估炎症对MRI的X-SIJ进展(MRI-SIJ)的影响。

三个中心对来自DESIR队列的新发axSpA患者基线和第2、5年的X-SIJ和MRI-SIJ进行评分。进展被定义为(1)由非影像学(nr)转变到影像学(r)骶髂关节炎(根据修订的纽约(mNY)标准)或替代标准,(2)至少一个等级的变化(3)至少一个等级的变化,但忽略从0级变为1级。基线炎症对5年X-SIJ损伤(mNY)的MRI-SIJ的影响通过广义估计方程进行评估。

在416例有基线和5年X-SIJ数据的患者中,从nr-axSpA向r- axSpA转变(1),至少一个等级的变化(2)或至少一个等级的变化,但忽略从0级变为1级(3),净进展分别为5.1%(1),13.0%(2)和10.3%(3)。在白细胞抗原B27(HLA-B27)阳性(OR 5.39(95%CI 3.25-8.94))和HLA-B27阴性(OR 2.16(95%CI 1.04-4.51))的患者中,基线MRI-SIJ可以预测5年后的结构性损害。

新发病的axSpA患者X-SIJ损伤的五年进展是有限的,但在测量误差外是真实存在的。基线MRI-SIJ炎症驱动5年的影像学变化。

原始出处:

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    2017-07-09 lmm397
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    2017-07-07 天涯183

    非常好的文章,学习了,很受益

    0

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    2017-07-07 1e1a50a1m36(暂无匿称)

    基线MRI-SIJ炎症驱动5年的影像学变化。

    0

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