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Obstet Gynecol：出生时从新生儿缺氧缺血性脑病中鉴别出动脉缺血性脑卒中的方法

2016-09-25 MedSci MedSci原创

缺血性脑卒中
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因此，研究数据表明新生儿脑卒中与增加的初始血小板计数有关，而与剖宫产不安全的胎心率曲线、突发事件或围产期代谢性酸中毒无关。脑卒中是一种不与围产期危险因素无关的新生儿脑损伤，这样可以允许对其进行早期识别。

近日，妇产科领域权威杂志《obstetrics and gynecology》发表了旨在探索从新生儿缺氧缺血性脑病中鉴别出动脉缺血性脑卒中的方法的文章，文章的作者Adami, Rebecca R医生将重心放在了围产期危险因素上。

该研究是一项，在2010年1月1日至2015年12月31日期间，所有研究者所在医院新生儿ICU而妊娠超过35周出生的新生儿纳入的队列研究，并且比较了新生儿脑卒中和因异常脑磁共振成像接受全身低温治疗的缺氧缺血性脑病的情况。在这6年期间，有22例新生儿脑卒中和47例因异常脑磁共振成像接受全身低温治疗的缺氧缺血性脑病。其中有3例新生儿进行低温治疗最初以为有缺氧缺血性脑病，后来被诊断为脑卒中。所有脑卒中新生儿血栓形成倾向检查为阴性。在单因素分析中，新生儿脑卒中患者癫痫发作的发生率和初始血小板计数明显增加。在出生6小时内，在单变量分析中P<0.1的变量在多变量模型上显著增加不安全的胎心率曲线、紧急事件、低Apgar评分和缺氧缺血性脑病新生儿代谢性酸中毒。新生儿脑卒中与增加的初始血小板计数显著相关。

因此，研究数据表明新生儿脑卒中与增加的初始血小板计数有关，而与剖宫产不安全的胎心率曲线、突发事件或围产期代谢性酸中毒无关。脑卒中是一种不与围产期危险因素无关的新生儿脑损伤，这样可以允许对其进行早期识别。

原始出处：

Adami, Rebecca R, et al. Distinguishing Arterial Ischemic Stroke From Hypoxic–Ischemic Encephalopathy in the Neonate at Birth.obstetrics and gynecology.2016. doi: 10.1097/AOG.0000000000001631

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    2017-06-18 zz70

    #缺氧缺血性脑病#

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    2017-06-01 guihongzh

    #缺血性#

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    2017-01-26 1249842em09(暂无昵称)

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    2017-03-23 yhy100200

    #TET#

    0

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    2017-01-14 showtest

    #脑病#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2085457, encodeId=9423208545e50, content=<a href='/topic/show?id=425ee9335b2' target=_blank style='color:#2F92EE;'>#缺氧缺血性脑病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79335, encryptionId=425ee9335b2, topicName=缺氧缺血性脑病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30f5146, createdName=zz70, createdTime=Sun Jun 18 12:21:00 CST 2017, time=2017-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1892795, encodeId=3bb61892e958e, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Thu Jun 01 02:21:00 CST 2017, time=2017-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2043918, encodeId=228a2043918a5, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Thu Jan 26 12:21:00 CST 2017, time=2017-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011254, encodeId=3dd620112543f, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Thu Mar 23 10:21:00 CST 2017, time=2017-03-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1666394, encodeId=aa68166639408, content=<a href='/topic/show?id=55c6849451c' target=_blank style='color:#2F92EE;'>#脑病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84945, encryptionId=55c6849451c, topicName=脑病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=db0126060584, createdName=showtest, createdTime=Sat Jan 14 19:21:00 CST 2017, time=2017-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1807024, encodeId=331a180e024ad, content=<a href='/topic/show?id=245de9378aa' target=_blank style='color:#2F92EE;'>#缺血性脑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79378, encryptionId=245de9378aa, topicName=缺血性脑)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLGtr9t89oicQdQSIeKmOQic1weIWfibJ7H24XnT8ic9wiaUMTnXByenuwicOj8Jib42ibHXNptnuiaKthhiaVw/132, createdBy=ac342500190, createdName=ms7524819409032184, createdTime=Sun May 14 22:21:00 CST 2017, time=2017-05-14, status=1, ipAttribution=)]
    2017-05-14 ms7524819409032184

    #缺血性脑#

    0

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