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Am J Ophthalmol Case Rep:内皮角膜移植术-DMEK

2018-09-29 MedSci MedSci原创

英国伦敦UCL眼科研究所的Parekh M近日在Am J Ophthalmol Case Rep发表了一篇文章,报告了采用大面积(9.5 mm)超薄Descemet膜自动剥离的内皮角膜移植术(UT-DSAEK)手术治疗大面积视觉功能障碍患者的过程,并详细讨论了手术中出现的并发症。

英国伦敦UCL眼科研究所的Parekh M近日在Am J Ophthalmol Case Rep发表了一篇文章,报告了采用大面积(9.5 mm)超薄Descemet膜自动剥离的内皮角膜移植术(UT-DSAEK)手术治疗大面积视觉功能障碍患者的过程,并详细讨论了手术中出现的并发症。

他们对一例89岁男性患有Fuchs角膜内皮营养的病例进行了研究。该患者需要进行大型UT-DSAEK,但由于移植物制备期间出现术中并发症,因此使用标准化的SCUBA技术从相同的移植物中制备了8.00mm Descemet膜,进行内皮角膜移植术(DMEK)。术后没有DM脱离,前房形成良好。对移植物的早期术后检查发现出现偏离中心,并出现角膜水肿。 3个月后检测发现内皮移植物附着良好,角膜水肿消失。5个月后,患者左眼的BSCVA是6/6(20/20),但存在轻度不适。在移植物周围观察到角膜水肿的圆环,观察到移植的移植物分散。第5个月时中央角膜的内皮细胞密度(ECD)为1506cells / mm2,焦深为496μm,同时出现一些聚集物。

因此,他们认为,可以从失败的DSAEK移植物中制备DMEK。在DMEK间接检查移植物中心、功能。在角膜恢复后,角膜断层扫描的厚度图是一个有用的诊断工具。

原文出处:

Parekh, M., et al., Descemet Membrane Endothelial Keratoplasty - Complication and management of a single case for tissue preparation and graft size linked to post-op descemetorhexis disparity. Am J Ophthalmol Case Rep, 2018. 12: p. 65-67.

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    2019-01-28 naiwu77
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    2019-01-15 cy0324
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    2019-04-11 charl1234567
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    2018-10-01 snowpeakxu
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  7. [GetPortalCommentsPageByObjectIdResponse(id=1943890, encodeId=a0cd194389059, content=<a href='/topic/show?id=d2af1152597' target=_blank style='color:#2F92EE;'>#MEK#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11525, encryptionId=d2af1152597, topicName=MEK)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b0e350, createdName=naiwu77, createdTime=Mon Jan 28 07:53:00 CST 2019, time=2019-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1926785, encodeId=87411926e85ba, content=<a href='/topic/show?id=8fee909e4a6' target=_blank style='color:#2F92EE;'>#角膜移植术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90974, encryptionId=8fee909e4a6, topicName=角膜移植术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca89104, createdName=huperzia, createdTime=Fri Jun 14 04:53:00 CST 2019, time=2019-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1998948, encodeId=87ee19989481f, content=<a href='/topic/show?id=8e2ee5200ee' target=_blank style='color:#2F92EE;'>#移植术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75200, encryptionId=8e2ee5200ee, topicName=移植术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Tue Jan 15 13:53:00 CST 2019, time=2019-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2027950, encodeId=13e1202e95057, content=<a href='/topic/show?id=7c9a41324e' target=_blank style='color:#2F92EE;'>#case#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4132, encryptionId=7c9a41324e, topicName=case)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=62a7397, createdName=charl1234567, createdTime=Thu Apr 11 13:53:00 CST 2019, time=2019-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1349154, encodeId=d67d1349154ce, content=<a href='/topic/show?id=4337909284a' target=_blank style='color:#2F92EE;'>#角膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90928, encryptionId=4337909284a, topicName=角膜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=568152, createdName=snowpeakxu, createdTime=Mon Oct 01 12:53:00 CST 2018, time=2018-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1541397, encodeId=6cbc154139ea4, content=<a href='/topic/show?id=5c961e37307' target=_blank style='color:#2F92EE;'>#THA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17373, encryptionId=5c961e37307, topicName=THA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=615b13300589, createdName=1249842em13(暂无昵称), createdTime=Mon Oct 01 12:53:00 CST 2018, time=2018-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1589604, encodeId=068115896040d, content=<a href='/topic/show?id=da41909e3a6' target=_blank style='color:#2F92EE;'>#角膜移植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90973, encryptionId=da41909e3a6, topicName=角膜移植)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8f3817754797, createdName=zhangj7114, createdTime=Mon Oct 01 12:53:00 CST 2018, time=2018-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624895, encodeId=cbea1624895e6, content=<a href='/topic/show?id=0333412062' target=_blank style='color:#2F92EE;'>#Cas#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4120, encryptionId=0333412062, topicName=Cas)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=411420689333, createdName=yaanren, createdTime=Mon Oct 01 12:53:00 CST 2018, time=2018-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629120, encodeId=1d071629120da, content=<a href='/topic/show?id=7a1a604538' target=_blank style='color:#2F92EE;'>#DME#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6045, encryptionId=7a1a604538, topicName=DME)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=713521313796, createdName=徐岩, createdTime=Mon Oct 01 12:53:00 CST 2018, time=2018-10-01, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1943890, encodeId=a0cd194389059, content=<a href='/topic/show?id=d2af1152597' target=_blank style='color:#2F92EE;'>#MEK#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11525, encryptionId=d2af1152597, topicName=MEK)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b0e350, createdName=naiwu77, createdTime=Mon Jan 28 07:53:00 CST 2019, time=2019-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1926785, encodeId=87411926e85ba, content=<a href='/topic/show?id=8fee909e4a6' target=_blank style='color:#2F92EE;'>#角膜移植术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90974, encryptionId=8fee909e4a6, topicName=角膜移植术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca89104, createdName=huperzia, createdTime=Fri Jun 14 04:53:00 CST 2019, time=2019-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1998948, encodeId=87ee19989481f, content=<a href='/topic/show?id=8e2ee5200ee' target=_blank style='color:#2F92EE;'>#移植术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75200, encryptionId=8e2ee5200ee, topicName=移植术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Tue Jan 15 13:53:00 CST 2019, time=2019-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2027950, encodeId=13e1202e95057, content=<a href='/topic/show?id=7c9a41324e' target=_blank style='color:#2F92EE;'>#case#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4132, encryptionId=7c9a41324e, topicName=case)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=62a7397, createdName=charl1234567, createdTime=Thu Apr 11 13:53:00 CST 2019, time=2019-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1349154, encodeId=d67d1349154ce, content=<a href='/topic/show?id=4337909284a' target=_blank style='color:#2F92EE;'>#角膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90928, encryptionId=4337909284a, topicName=角膜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=568152, createdName=snowpeakxu, createdTime=Mon Oct 01 12:53:00 CST 2018, time=2018-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1541397, encodeId=6cbc154139ea4, content=<a href='/topic/show?id=5c961e37307' target=_blank style='color:#2F92EE;'>#THA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17373, encryptionId=5c961e37307, topicName=THA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=615b13300589, createdName=1249842em13(暂无昵称), createdTime=Mon Oct 01 12:53:00 CST 2018, time=2018-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1589604, encodeId=068115896040d, content=<a href='/topic/show?id=da41909e3a6' target=_blank style='color:#2F92EE;'>#角膜移植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90973, encryptionId=da41909e3a6, topicName=角膜移植)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8f3817754797, createdName=zhangj7114, createdTime=Mon Oct 01 12:53:00 CST 2018, time=2018-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624895, encodeId=cbea1624895e6, content=<a href='/topic/show?id=0333412062' target=_blank style='color:#2F92EE;'>#Cas#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4120, encryptionId=0333412062, topicName=Cas)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=411420689333, createdName=yaanren, createdTime=Mon Oct 01 12:53:00 CST 2018, time=2018-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629120, encodeId=1d071629120da, content=<a href='/topic/show?id=7a1a604538' target=_blank style='color:#2F92EE;'>#DME#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6045, encryptionId=7a1a604538, topicName=DME)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=713521313796, createdName=徐岩, createdTime=Mon Oct 01 12:53:00 CST 2018, time=2018-10-01, status=1, ipAttribution=)]
    2018-10-01 yaanren
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    2018-10-01 徐岩
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