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Int J Pediatr Otorhinolaryngol:射频消融鼻甲成形术可改善儿科患者的嗅觉

2021-11-09 AlexYang MedSci原创

评估了首次接受TRA小儿患者的嗅觉变化情况。

嗅觉对儿童的充分发育至关重要。儿童的嗅觉丧失有着不同的起因,其中最常见的是传导性原因,即鼻腔阻塞使气味无法到达嗅觉上皮细胞。目前,已证明鼻炎和鼻甲肥大会削弱小儿患者的嗅觉。对于这些患者的鼻炎,常见的治疗方法是鼻甲射频消融术(TRA)。尽管该领域的研究力度很大,但迄今为止还没有研究对接受鼻甲手术儿童的嗅觉进行评估

近期,来自西班牙的研究人员在《Int J Pediatr Otorhinolaryngol》上发表文章,评估了首次接受TRA小儿患者的嗅觉变化情况

研究为前瞻性的非受控干预性临床试验设计。在一家三级转诊医院选取了两组4-15岁的儿童,并在术前和术后1、3、6个月分别用通用嗅觉测试(U-Sniff)、酒精嗅觉测试(AST)和嗅棒阈值测试(SST)进行评估。队列A包括仅接受TRA的儿童。队列B由进行过腺样体切除术和TRA的儿童组成。此外,还包括了健康对照组,并按性别和年龄配对,并进行嗅觉测试。

研究共纳入了81名参与者,平均年龄为10.31±2.56岁。53名患者接受TRA,28名患者接受相关的腺样体切除术。结果发现,尽管U-sniff评分在术后有改善的趋势,但没有统计学上的显著差异。然而,SST和AST测量结果具有统计学上的显著差异,包括手术后1个月、3个月和6个月。

术前和术后1、3、6个月的U-Sniff测试结果

综上所述,TRA或TRA与腺样体切除术联用,可改善嗅觉阈值得分,但对鉴别任务没有明显影响

原始出处:

Christian Calvo-Henriquez, Franklin Mariiño-Sánchez, Jerome R Lechien et al. Radiofrequency ablation turbinoplasty improves the sense of smell in pediatric patients: A prospective study. Int J Pediatr Otorhinolaryngol. Nov 2021

 

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    2022-10-13 feather89
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    2021-11-09 丙泊酚的米

    学习赚积分

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