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JAMA:全球研究发现收缩压大于110-115 mmHg造成的危害增加

2017-01-12 MedSci MedSci原创

近些年来,由于血压升高而导致的健康损失在不同的国家发生了很大的变化,虽然这是一种高度可治愈的疾病,然而不幸地是在世界许多地方都没有得到相应的治疗。最近的一项基于全球疾病、损伤和危险因素负担2015(GBD 2015)数据的分析研究发现:在过去的25年中,收缩压(SBP)升高人群的数量大大增加,同样地收缩压升高相关的死亡和劳力丧失修正寿命年(disability-adjusted life-year

近些年来,由于血压升高而导致的健康损失在不同的国家发生了很大的变化,虽然这是一种高度可治愈的疾病,然而不幸地是在世界许多地方都没有得到相应的治疗。

最近的一项基于全球疾病、损伤和危险因素负担2015(GBD 2015)数据的分析研究发现:在过去的25年中,收缩压(SBP)升高人群的数量大大增加,同样地收缩压升高相关的死亡和劳力丧失修正寿命年(disability-adjusted life-years,DALYs)也大大增多。该研究结果发表在今年1月10日的《美国医学协会杂志》(JAMA)上。

研究人员收集并分析了来自154个国家的研究中的869万名患者的数据,同时应用41个其他国家的模型估算了国家水平的SBP升高率和因心脏病、中风、房颤、心肌病、主动脉瘤、周围血管病、风湿性心脏病、心内膜炎、慢性肾脏病等SBP升高相关的心血管疾病造成的死亡和DALYs损失。

研究人员估计,从1990到2015,收缩压大于110到115mmHg的人数上升了11%(从1亿8700万到3亿4700万),收缩压大于等于140 mm Hg的人群上升了18%(从6千万到9千万)。

同时,收缩压大于110-115mmHg相关的死亡人数上升了49%(从720万到1070万),而那些收缩压大于等于140mmHg相关的死亡人数上升了51%(从520万到780万)。与此同时,收缩压大于110-115mmHg相关的DALYs损失从1亿4700万增加到2亿1200万;收缩压大于等于140mmHg相关的DALYs损失增加地更多,从9600万增加到了1亿4300万。

收缩压大于110-115mmHg相关的DALYs损失中有超过一半的来自下面五个国家:中国、印度、俄罗斯、印度尼西亚和美国,主要是因为这些国家人口基数比较大。

根据研究结果,研究人员发现:在高质量的前瞻性队列研究中,收缩压大于110-115 mmHg造成的死亡风险增加;而医生们一直以来进行降压治疗和高血压诊断的临界值则是收缩压大于140 mmHg。

但是,来自芝加哥西北大学费因伯格医学院的Mark D Huffman和Donald M Lloyd-Jones在一篇社论中警告说:该研究的数据不能指导临床实践指南确定降脂治疗或降压治疗启动时的血压水平。但是,这些数据告诉人们应大力降低收缩压大于等于140 mm Hg人群患心血管疾病的风险,如提高健康饮食的摄取,降低体重或在超重或肥胖人群中促进减肥,促进降血压药物应用和持续应用以及心血管疾病相关风险的管理。

该研究作者也表示,虽然该研究还没有强有力的证据表明,每个人都应该在135mmHg时接受降压药物治疗,但是可以接受其它干预措施,如改变生活方式或在生命早期开始健康的生活方式,这些都是减轻负担的重要途径。

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    2017-01-14 wolixiang2012

    原来是这样的评论

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1840301, encodeId=69a618403017b, content=<a href='/topic/show?id=10905e20546' target=_blank style='color:#2F92EE;'>#收缩压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57205, encryptionId=10905e20546, topicName=收缩压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Tue Jan 31 07:42:00 CST 2017, time=2017-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1753170, encodeId=79cb1e53170e3, content=<a href='/topic/show?id=6a57e33772b' target=_blank style='color:#2F92EE;'>#研究发现#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73377, encryptionId=6a57e33772b, topicName=研究发现)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e1736602208, createdName=hanhaisha2020, createdTime=Wed May 31 01:42:00 CST 2017, time=2017-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=170171, encodeId=e6301e017114, content=原来是这样的评论, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d2e4105146, createdName=wolixiang2012, createdTime=Sat Jan 14 00:05:52 CST 2017, time=2017-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=170124, encodeId=12df1e0124eb, content=药物不是必须的应该改变生活方式或在生命早期开始健康的生活方式,, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Fri Jan 13 17:49:08 CST 2017, time=2017-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=170051, encodeId=bcb61e0051cf, content=恩,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Fri Jan 13 12:39:29 CST 2017, time=2017-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169946, encodeId=9e901699465f, content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Thu Jan 12 23:26:17 CST 2017, time=2017-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169916, encodeId=1f04169916de, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Thu Jan 12 20:53:41 CST 2017, time=2017-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169911, encodeId=c515169911dc, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Thu Jan 12 20:49:14 CST 2017, time=2017-01-12, status=1, ipAttribution=)]
    2017-01-13 为了宝宝

    药物不是必须的应该改变生活方式或在生命早期开始健康的生活方式,

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1840301, encodeId=69a618403017b, content=<a href='/topic/show?id=10905e20546' target=_blank style='color:#2F92EE;'>#收缩压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57205, encryptionId=10905e20546, topicName=收缩压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Tue Jan 31 07:42:00 CST 2017, time=2017-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1753170, encodeId=79cb1e53170e3, content=<a href='/topic/show?id=6a57e33772b' target=_blank style='color:#2F92EE;'>#研究发现#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73377, encryptionId=6a57e33772b, topicName=研究发现)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e1736602208, createdName=hanhaisha2020, createdTime=Wed May 31 01:42:00 CST 2017, time=2017-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=170171, encodeId=e6301e017114, content=原来是这样的评论, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d2e4105146, createdName=wolixiang2012, createdTime=Sat Jan 14 00:05:52 CST 2017, time=2017-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=170124, encodeId=12df1e0124eb, content=药物不是必须的应该改变生活方式或在生命早期开始健康的生活方式,, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Fri Jan 13 17:49:08 CST 2017, time=2017-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=170051, encodeId=bcb61e0051cf, content=恩,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Fri Jan 13 12:39:29 CST 2017, time=2017-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169946, encodeId=9e901699465f, content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Thu Jan 12 23:26:17 CST 2017, time=2017-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169916, encodeId=1f04169916de, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Thu Jan 12 20:53:41 CST 2017, time=2017-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169911, encodeId=c515169911dc, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Thu Jan 12 20:49:14 CST 2017, time=2017-01-12, status=1, ipAttribution=)]
    2017-01-13 天涯183

    恩,学习了

    0

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    2017-01-12 忠诚向上

    好好学习

    0

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    2017-01-12 李东泽

    很好,不错,以后会多学习

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1840301, encodeId=69a618403017b, content=<a href='/topic/show?id=10905e20546' target=_blank style='color:#2F92EE;'>#收缩压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57205, encryptionId=10905e20546, topicName=收缩压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Tue Jan 31 07:42:00 CST 2017, time=2017-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1753170, encodeId=79cb1e53170e3, content=<a href='/topic/show?id=6a57e33772b' target=_blank style='color:#2F92EE;'>#研究发现#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73377, encryptionId=6a57e33772b, topicName=研究发现)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e1736602208, createdName=hanhaisha2020, createdTime=Wed May 31 01:42:00 CST 2017, time=2017-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=170171, encodeId=e6301e017114, content=原来是这样的评论, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d2e4105146, createdName=wolixiang2012, createdTime=Sat Jan 14 00:05:52 CST 2017, time=2017-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=170124, encodeId=12df1e0124eb, content=药物不是必须的应该改变生活方式或在生命早期开始健康的生活方式,, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Fri Jan 13 17:49:08 CST 2017, time=2017-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=170051, encodeId=bcb61e0051cf, content=恩,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Fri Jan 13 12:39:29 CST 2017, time=2017-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169946, encodeId=9e901699465f, content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Thu Jan 12 23:26:17 CST 2017, time=2017-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169916, encodeId=1f04169916de, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Thu Jan 12 20:53:41 CST 2017, time=2017-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=169911, encodeId=c515169911dc, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Thu Jan 12 20:49:14 CST 2017, time=2017-01-12, status=1, ipAttribution=)]
    2017-01-12 doctorJiangchao

    继续学习

    0

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