Baidu
map

Mol Psychiatry:啥?抗炎药也可以治疗抑郁?

2016-10-20 MedSci MedSci原创

一项系统回顾和荟萃分析的结果表明,抗细胞因子治疗抑郁症是有效的!这表明,这些药物可能对抑郁症和相关疾病有潜在的治疗作用。 剑桥大学的Golam Khandaker博士说:越来越多的证据表明,炎症在抑郁症中起着一定作用;这项系统回顾和荟萃分析也表明,抗炎治疗对抑郁症有益!不过这种抗炎药不是我们平时使用的消炎药如布洛芬,而是某一类新的药物。 为了评估细胞因子在抑郁症的发病机制和治疗中的潜在

一项系统回顾和荟萃分析的结果表明,抗细胞因子治疗抑郁症是有效的!这表明,这些药物可能对抑郁症和相关疾病有潜在的治疗作用。 剑桥大学的Golam Khandaker博士说:越来越多的证据表明,炎症在抑郁症中起着一定作用;这项系统回顾和荟萃分析也表明,抗炎治疗对抑郁症有益!不过这种抗炎药不是我们平时使用的消炎药如布洛芬,而是某一类新的药物。 为了评估细胞因子在抑郁症的发病机制和治疗中的潜在作用,研究人员对20项临床试验进行了系统回顾和荟萃分析。 7项随机对照试验(涉及2370名受访者)进行的荟萃分析结果表明,抗细胞因子治疗有明显的抗抑郁作用(与安慰剂组相比,平均数标准差= 0.4; 95% CI, 0.22-0.59)。 抗肿瘤坏死因子药物是最常用的研究药物,与安慰剂组相比,标准化的平均差异为0.33 (95% CI, 0.06-0.6)。 对2项抗细胞因子治疗的随机临床试验和8项非随机或非对照研究进行单独的荟萃分析,表现出了类似的效果,抗细胞因子治疗对抑郁有小到中等程度的疗效。 阿达木单抗(Humira, AbbVie Inc.)、依那西普(Enbrel, Amgen)、英夫

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1792018, encodeId=34a21e9201827, content=<a href='/topic/show?id=696a14818df' target=_blank style='color:#2F92EE;'>#Psychiatry#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14818, encryptionId=696a14818df, topicName=Psychiatry)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Wed Jun 14 00:56:00 CST 2017, time=2017-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2023874, encodeId=cc6820238e447, content=<a href='/topic/show?id=99ff64628fb' target=_blank style='color:#2F92EE;'>#治疗抑郁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64628, encryptionId=99ff64628fb, topicName=治疗抑郁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f5e185, createdName=zlawrance, createdTime=Thu Jul 20 18:56:00 CST 2017, time=2017-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346732, encodeId=ae251346e3282, content=<a href='/topic/show?id=f20155404fc' target=_blank style='color:#2F92EE;'>#抗炎药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55404, encryptionId=f20155404fc, topicName=抗炎药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Sat Oct 22 08:56:00 CST 2016, time=2016-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150015, encodeId=d1231500155a, content=一药两用,额外好处, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161012/IMG57FE37B9D8B7C2781.jpg, createdBy=05f31956923, createdName=1e128d2fm65(暂无匿称), createdTime=Thu Oct 20 22:39:17 CST 2016, time=2016-10-20, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1792018, encodeId=34a21e9201827, content=<a href='/topic/show?id=696a14818df' target=_blank style='color:#2F92EE;'>#Psychiatry#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14818, encryptionId=696a14818df, topicName=Psychiatry)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Wed Jun 14 00:56:00 CST 2017, time=2017-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2023874, encodeId=cc6820238e447, content=<a href='/topic/show?id=99ff64628fb' target=_blank style='color:#2F92EE;'>#治疗抑郁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64628, encryptionId=99ff64628fb, topicName=治疗抑郁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f5e185, createdName=zlawrance, createdTime=Thu Jul 20 18:56:00 CST 2017, time=2017-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346732, encodeId=ae251346e3282, content=<a href='/topic/show?id=f20155404fc' target=_blank style='color:#2F92EE;'>#抗炎药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55404, encryptionId=f20155404fc, topicName=抗炎药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Sat Oct 22 08:56:00 CST 2016, time=2016-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150015, encodeId=d1231500155a, content=一药两用,额外好处, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161012/IMG57FE37B9D8B7C2781.jpg, createdBy=05f31956923, createdName=1e128d2fm65(暂无匿称), createdTime=Thu Oct 20 22:39:17 CST 2016, time=2016-10-20, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1792018, encodeId=34a21e9201827, content=<a href='/topic/show?id=696a14818df' target=_blank style='color:#2F92EE;'>#Psychiatry#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14818, encryptionId=696a14818df, topicName=Psychiatry)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Wed Jun 14 00:56:00 CST 2017, time=2017-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2023874, encodeId=cc6820238e447, content=<a href='/topic/show?id=99ff64628fb' target=_blank style='color:#2F92EE;'>#治疗抑郁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64628, encryptionId=99ff64628fb, topicName=治疗抑郁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f5e185, createdName=zlawrance, createdTime=Thu Jul 20 18:56:00 CST 2017, time=2017-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346732, encodeId=ae251346e3282, content=<a href='/topic/show?id=f20155404fc' target=_blank style='color:#2F92EE;'>#抗炎药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55404, encryptionId=f20155404fc, topicName=抗炎药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Sat Oct 22 08:56:00 CST 2016, time=2016-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150015, encodeId=d1231500155a, content=一药两用,额外好处, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161012/IMG57FE37B9D8B7C2781.jpg, createdBy=05f31956923, createdName=1e128d2fm65(暂无匿称), createdTime=Thu Oct 20 22:39:17 CST 2016, time=2016-10-20, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1792018, encodeId=34a21e9201827, content=<a href='/topic/show?id=696a14818df' target=_blank style='color:#2F92EE;'>#Psychiatry#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14818, encryptionId=696a14818df, topicName=Psychiatry)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Wed Jun 14 00:56:00 CST 2017, time=2017-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2023874, encodeId=cc6820238e447, content=<a href='/topic/show?id=99ff64628fb' target=_blank style='color:#2F92EE;'>#治疗抑郁#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64628, encryptionId=99ff64628fb, topicName=治疗抑郁)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f5e185, createdName=zlawrance, createdTime=Thu Jul 20 18:56:00 CST 2017, time=2017-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346732, encodeId=ae251346e3282, content=<a href='/topic/show?id=f20155404fc' target=_blank style='color:#2F92EE;'>#抗炎药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55404, encryptionId=f20155404fc, topicName=抗炎药)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Sat Oct 22 08:56:00 CST 2016, time=2016-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150015, encodeId=d1231500155a, content=一药两用,额外好处, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161012/IMG57FE37B9D8B7C2781.jpg, createdBy=05f31956923, createdName=1e128d2fm65(暂无匿称), createdTime=Thu Oct 20 22:39:17 CST 2016, time=2016-10-20, status=1, ipAttribution=)]
    2016-10-20 1e128d2fm65(暂无匿称)

    一药两用,额外好处

    0

相关资讯

强生抗炎药SIMPONI获欧盟CHMP支持批准,治疗多关节型幼年特发性关节炎(pJIA)

美国医药巨头强生(JNJ)重磅单抗药物Simponi(golimumab,戈利木单抗)近日在欧盟监管方面传来喜讯。欧洲药品管理局(EMA)人用医药产品委员会(CHMP)支持批准皮下注射药物Simponi联合甲氨蝶呤(MTX),用于对既往甲氨蝶呤治疗反应不足、体重至少40公斤、年龄17岁以下的多关节型幼年特发性关节炎(pJIA)儿童患者的治疗。 pJIA是17岁以下儿童群体中最常见的关节炎类型

ACC 2012:口服抗炎药减少BMS支架内晚期丢失

  2012年3月24日 ,美国心脏病学会(ACC)2012年会报告的一项小规模试验性研究证明,稳定性冠心病患者在经皮冠状动脉介入治疗(PCI)中如用裸金属支架治疗,加用宾达利(bindarit)可显著改善6个月后的血管造影结果。宾达利是一种口服抗炎药,可选择性抑制单核细胞趋化蛋白;与安慰剂组相比,宾达利治疗可显著减少置入裸金属支架后的支架内晚期丢失。   意大利哥伦布医院Antonio Col

研究发现抗炎药具有癌症治疗前景

来自斯克利普斯研究机构的科学家们发现,一种目前运用最为广泛的抗炎药物能够抑制动物模型中特定类型肿瘤的生长。这项新的研究发表在《癌症研究》在线版上,专注于塞来昔布(西乐葆,辉瑞公司)对肿瘤的影响。 塞来昔布是常用的非甾体类抗炎药,作用靶点为环氧化酶-2(COX-2),COX-2是一种与体内炎症相关的酶类,此外,该酶在促进肿瘤的生长过程中也起着关键作用。COX-2在正常组织中

Baidu
map
Baidu
map
Baidu
map