Brit J Cancer：癌症患者COVID-19死亡风险

2021-08-17 网络网络

该研究结果进一步证实了男性和亚洲癌症患者、血液系统恶性肿瘤或诊断2年以上的癌症患者COVID-19的死亡风险增加。在为癌症患者做临床决定时，应考虑这些因素。

近日，肿瘤学领域权威杂志British Journal of Cancer上发表了一篇研究文章，研究人员旨在明确与COVID-19死亡相关的癌症患者特征。

研究人员使用了2020年2月29日至7月31日期间在盖伊癌症中心和国王学院医院就诊的严重急性呼吸综合征冠状病毒-2(SARS-CoV-2)逆转录聚合酶链反应咽拭子阳性的所有癌症患者的数据，并进行Cox比例风险回归以确定哪些因素与COVID-19死亡率相关。

该研究纳入306例SARS-CoV-2阳性的肿瘤患者。71%的患者为轻度/中度COVID-19，29%的患者为重度COVID-19。72例(24%)患者死于COVID-19，其中35例患者死亡时间小于7天。男性[风险比(HR):1.97(95%置信区间(CI):1.15-3.38)]、亚裔[3.42(1.59-7.35)]、血液系统癌症[2.03(1.16-3.56)]和癌症诊断>2-5年[2.81(1.41-5.59)]或≥5年与死亡率增加相关。

年龄>60岁和c反应蛋白(CRP)升高也与COVID-19死亡相关。血液系统癌症、诊断时伴有呼吸困难和CRP升高提示癌症患者(确诊后7天内)发生COVID-19相关的早期死亡。

由此可见，该研究结果进一步证实了男性和亚洲癌症患者、血液系统恶性肿瘤或诊断2年以上的癌症患者COVID-19的死亡风险增加。在为癌症患者做临床决定时，应考虑这些因素。

原始出处：

Beth Russell.et al.Risk of COVID-19 death in cancer patients: an analysis from Guy’s Cancer Centre and King’s College Hospital in London.Brit J Cancer.2021.https://www.nature.com/articles/s41416-021-01500-z

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#插入话题

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2021-08-19 quxin068

#死亡风险#

76 0
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2021-08-19 zgwhgch

#癌症患者#

65 0
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2021-08-18 tanxingdoctor

学习了

0 0
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2021-08-18 智慧药

学习学习

102 0
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2021-08-18 涂涂0518

学习了

89 0
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2021-08-18 Linsanity

学到了

0 0
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2021-08-18 小火龙111

nice

118 0

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