Baidu
map

HUMAN BRAIN MAPPING:左楔前叶、左弓状束与语言学习能力有关

2021-07-22 MedSci原创 MedSci原创

人们学习新语言的成功程度各不相同,但语言学习能力差异的神经解剖学相关因素是什么?

人们学习新语言的成功程度各不相同,但语言学习能力差异的神经解剖学相关因素是什么?

HUMAN BRAIN MAPPING杂志最近发表研究文章利用LLAMA测验和超高场强磁共振成像研究语言学习倾向的神经解剖学相关性。这项研究调查了大脑皮层形态和白质微结构的差异如何与词汇学习、语音记忆和语法推理的能力相关。

使该研究用超高场强MRI的好处在于提高了信噪比和连续组织对比度,允许高分辨率、限制部分体积效应,并从T1加权图像体积中产生更有效的组织分割。与以往的研究相比,该研究通过使用更高的空间分辨率,有助于理解语言学习能力的结构神经相关性,作为皮质形态计量学的基础。此外,与标准DTI相比,利用DKI可以计算相关白质束的更详细的组织微结构参数。

该研究使用超高场(7T)磁共振成像来估计皮质厚度和表面积从亚毫米分辨率的图像体积。此外,扩散峰度成像用于绘制与已知语言相关白质束的组织微结构相关的扩散特性。

FreeSurfer重建示例。软脑膜表面以红色显示,白表面(白质/灰质边界)以蓝色显示

左后下楔前叶皮质表面积与词汇学习能力之间存在相关性,这可能表明存在更大的词汇-图形联想倾向。

以eICV和年龄为协变量,词汇学习能力倾向评分(LLAMA B)与覆盖左下后楔的左后内侧皮层表面积相关。

语音记忆倾向(LLAMA D)与左弓状束(AF)轴向峰度(AK)和左上纵束(III)轴向峰度(AK)相关。AF(蓝色)和SLF III(绿色)

此外,左弓状束的语音记忆分数和轴向峰度以及左上纵束III的平均峰度、轴向峰度和径向峰度之间的负相关,这是连接对语音工作记忆重要的皮质区域的束。

总之,该研究结果表明,左后内侧群较大的皮层表面有利于词汇学习能力的培养,这可能反映了语言相关的词汇-图形联想具有更大的陈述性记忆储存能力。此外,已知背侧语言加工流束的峰度参数与语音记忆呈负相关,这表明白质束的一致性和均一性对语音工作记忆的影响,这些白质束连接着负责语音存储的众所周知的皮层区域。该研究增加了关于大脑皮层厚度、皮层表面积和白质纤维束的组织微结构如何与学习语言能力相关的知识。从更广的角度来看,这也意味着,能力和才能的差异至少部分可能是由于大脑皮层形态计量学或白质微观结构的差异造成的。

原文出处

Cortical and white matter correlates of language-learning aptitudes. https://doi.org/10.1002/hbm.25598

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1940450, encodeId=2841194045048, content=<a href='/topic/show?id=0de4919efc' target=_blank style='color:#2F92EE;'>#human#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9197, encryptionId=0de4919efc, topicName=human)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=674961, createdName=tamgche, createdTime=Sun Apr 24 11:11:23 CST 2022, time=2022-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1947655, encodeId=dd23194e6554f, content=<a href='/topic/show?id=974d112896d' target=_blank style='color:#2F92EE;'>#mapping#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11289, encryptionId=974d112896d, topicName=mapping)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Fri May 13 05:11:23 CST 2022, time=2022-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1418221, encodeId=a2ec141822160, content=<a href='/topic/show?id=a4719180605' target=_blank style='color:#2F92EE;'>#语言#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91806, encryptionId=a4719180605, topicName=语言)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c16b3335392, createdName=yangjxjc, createdTime=Fri Jul 23 15:11:23 CST 2021, time=2021-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629437, encodeId=7324162943e5d, content=<a href='/topic/show?id=a4a84548ea9' target=_blank style='color:#2F92EE;'>#学习能力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45487, encryptionId=a4a84548ea9, topicName=学习能力)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1ef421335630, createdName=wolongzxh, createdTime=Fri Jul 23 15:11:23 CST 2021, time=2021-07-23, status=1, ipAttribution=)]
    2022-04-24 tamgche
  2. [GetPortalCommentsPageByObjectIdResponse(id=1940450, encodeId=2841194045048, content=<a href='/topic/show?id=0de4919efc' target=_blank style='color:#2F92EE;'>#human#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9197, encryptionId=0de4919efc, topicName=human)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=674961, createdName=tamgche, createdTime=Sun Apr 24 11:11:23 CST 2022, time=2022-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1947655, encodeId=dd23194e6554f, content=<a href='/topic/show?id=974d112896d' target=_blank style='color:#2F92EE;'>#mapping#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11289, encryptionId=974d112896d, topicName=mapping)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Fri May 13 05:11:23 CST 2022, time=2022-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1418221, encodeId=a2ec141822160, content=<a href='/topic/show?id=a4719180605' target=_blank style='color:#2F92EE;'>#语言#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91806, encryptionId=a4719180605, topicName=语言)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c16b3335392, createdName=yangjxjc, createdTime=Fri Jul 23 15:11:23 CST 2021, time=2021-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629437, encodeId=7324162943e5d, content=<a href='/topic/show?id=a4a84548ea9' target=_blank style='color:#2F92EE;'>#学习能力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45487, encryptionId=a4a84548ea9, topicName=学习能力)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1ef421335630, createdName=wolongzxh, createdTime=Fri Jul 23 15:11:23 CST 2021, time=2021-07-23, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1940450, encodeId=2841194045048, content=<a href='/topic/show?id=0de4919efc' target=_blank style='color:#2F92EE;'>#human#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9197, encryptionId=0de4919efc, topicName=human)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=674961, createdName=tamgche, createdTime=Sun Apr 24 11:11:23 CST 2022, time=2022-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1947655, encodeId=dd23194e6554f, content=<a href='/topic/show?id=974d112896d' target=_blank style='color:#2F92EE;'>#mapping#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11289, encryptionId=974d112896d, topicName=mapping)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Fri May 13 05:11:23 CST 2022, time=2022-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1418221, encodeId=a2ec141822160, content=<a href='/topic/show?id=a4719180605' target=_blank style='color:#2F92EE;'>#语言#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91806, encryptionId=a4719180605, topicName=语言)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c16b3335392, createdName=yangjxjc, createdTime=Fri Jul 23 15:11:23 CST 2021, time=2021-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629437, encodeId=7324162943e5d, content=<a href='/topic/show?id=a4a84548ea9' target=_blank style='color:#2F92EE;'>#学习能力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45487, encryptionId=a4a84548ea9, topicName=学习能力)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1ef421335630, createdName=wolongzxh, createdTime=Fri Jul 23 15:11:23 CST 2021, time=2021-07-23, status=1, ipAttribution=)]
    2021-07-23 yangjxjc
  4. [GetPortalCommentsPageByObjectIdResponse(id=1940450, encodeId=2841194045048, content=<a href='/topic/show?id=0de4919efc' target=_blank style='color:#2F92EE;'>#human#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9197, encryptionId=0de4919efc, topicName=human)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=674961, createdName=tamgche, createdTime=Sun Apr 24 11:11:23 CST 2022, time=2022-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1947655, encodeId=dd23194e6554f, content=<a href='/topic/show?id=974d112896d' target=_blank style='color:#2F92EE;'>#mapping#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11289, encryptionId=974d112896d, topicName=mapping)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Fri May 13 05:11:23 CST 2022, time=2022-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1418221, encodeId=a2ec141822160, content=<a href='/topic/show?id=a4719180605' target=_blank style='color:#2F92EE;'>#语言#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91806, encryptionId=a4719180605, topicName=语言)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c16b3335392, createdName=yangjxjc, createdTime=Fri Jul 23 15:11:23 CST 2021, time=2021-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629437, encodeId=7324162943e5d, content=<a href='/topic/show?id=a4a84548ea9' target=_blank style='color:#2F92EE;'>#学习能力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45487, encryptionId=a4a84548ea9, topicName=学习能力)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1ef421335630, createdName=wolongzxh, createdTime=Fri Jul 23 15:11:23 CST 2021, time=2021-07-23, status=1, ipAttribution=)]

相关资讯

NeuroImage:MK-Curve提高了识别临床精神病高危患者白质改变的敏感性

该研究发现CHR患者的FA和MK较低,这与以前在精神病谱系中报道的dMRI发现一致。在MK曲线校正后,发现FA和MK异常广泛且重叠。

Eur Radiol:APT与DKI在诊断乳腺癌中孰优孰劣?

DKI是一种可以反映组织的微结构复杂性的扩散成像技术。APT是一种分子成像技术,可以在不使用外源性造影剂的情况下测量组织中的游离蛋白和多肽水平。

Baidu
map
Baidu
map
Baidu
map